Detailed information NTG1009776

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: H0511_RS07600
• Genome accession: NZ_LR822017
• Coordinates: 1492217..1493002 (-)
• Length: 261 a.a.
• NCBI ID: WP_164135571.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_336
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1487217..1498002

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0511_RS07565 (STHERMO_1696)	gatC	1487701..1488003 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
H0511_RS07570 (STHERMO_1697)	-	1488144..1488350 (-)	207	WP_232087148.1	glycosyltransferase	-
H0511_RS07575 (STHERMO_1698)	-	1488251..1488622 (-)	372	WP_332068334.1	glycosyltransferase	-
H0511_RS07580	-	1488938..1489951 (-)	1014	Protein_1460	family 1 glycosylhydrolase	-
H0511_RS07585 (STHERMO_1702)	msrA	1490104..1490613 (-)	510	WP_002951714.1	peptide-methionine (S)-S-oxide reductase MsrA	-
H0511_RS07590 (STHERMO_1703)	-	1490625..1491473 (-)	849	WP_179973029.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
H0511_RS07595 (STHERMO_1704)	-	1491597..1492154 (-)	558	WP_179973954.1	cysteine hydrolase family protein	-
H0511_RS07600 (STHERMO_1705)	codY	1492217..1493002 (-)	786	WP_164135571.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
H0511_RS07605 (STHERMO_1706)	-	1493260..1494474 (-)	1215	WP_179973955.1	pyridoxal phosphate-dependent aminotransferase	-
H0511_RS07610 (STHERMO_1707)	-	1494829..1495281 (+)	453	WP_179973956.1	universal stress protein	-
H0511_RS10140	-	1495461..1496032 (+)	572	Protein_1467	IS30 family transposase	-
H0511_RS07615 (STHERMO_1710)	-	1496104..1496277 (-)	174	WP_179973957.1	hypothetical protein	-
H0511_RS07620 (STHERMO_1711)	-	1496338..1496712 (-)	375	WP_179973958.1	hypothetical protein	-
H0511_RS07625 (STHERMO_1712)	pflA	1496923..1497723 (-)	801	WP_179973959.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28900.98 Da
• Isoelectric Point: 4.4150

>NTDB_id=1009776 H0511_RS07600 WP_164135571.1 1492217..1493002(-) (codY) [Streptococcus thermophilus isolate STH_CIRM_336]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGTLLGYAMKYKTNNDRVEEFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVESKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIAATVVGLQLLN
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=1009776 H0511_RS07600 WP_164135571.1 1492217..1493002(-) (codY) [Streptococcus thermophilus isolate STH_CIRM_336]
ATGGCAAATTTACTTGATAAAACACGCAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATATAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATCGTAAATGGTGGAGGTACTCTCCTTG
GTTATGCTATGAAATACAAAACCAACAATGACCGTGTGGAAGAGTTTTTTAAAGCGAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATCAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCAGCTACAGTAGTTGGTTTGCAATTGTTGAAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATCACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGTACTTACCTTAAAGTCCTTAACGAAGGTATCTACGATAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	65.759	98.467	0.648
codY	Bacillus subtilis subsp. subtilis str. 168	53.441	94.636	0.506