Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   H0503_RS08215 Genome accession   NZ_LR822009
Coordinates   1592172..1594523 (+) Length   783 a.a.
NCBI ID   WP_179971436.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_19     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1587172..1599523
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0503_RS08195 (STHERMO_1848) - 1587826..1587996 (-) 171 WP_232085863.1 hypothetical protein -
  H0503_RS08200 (STHERMO_1849) - 1588180..1588407 (-) 228 WP_011681629.1 hypothetical protein -
  H0503_RS08205 (STHERMO_1850) - 1588394..1588708 (-) 315 WP_014608696.1 hypothetical protein -
  H0503_RS08210 (STHERMO_1851) polA 1589326..1591965 (-) 2640 WP_011681632.1 DNA polymerase I -
  H0503_RS08215 (STHERMO_1852) mutS/mutS2 1592172..1594523 (+) 2352 WP_179971436.1 endonuclease MutS2 Machinery gene
  H0503_RS08220 (STHERMO_1853) - 1594624..1595166 (-) 543 WP_179971060.1 CvpA family protein -
  H0503_RS08225 (STHERMO_1854) - 1595163..1595480 (-) 318 WP_002947863.1 hypothetical protein -
  H0503_RS08230 (STHERMO_1855) rnhC 1595794..1596684 (+) 891 WP_011681634.1 ribonuclease HIII -
  H0503_RS08235 (STHERMO_1856) lepB 1596703..1597326 (+) 624 WP_002947854.1 signal peptidase I -

Sequence

Protein


Download         Length: 783 a.a.        Molecular weight: 88103.52 Da        Isoelectric Point: 6.6236

>NTDB_id=1009072 H0503_RS08215 WP_179971436.1 1592172..1594523(+) (mutS/mutS2) [Streptococcus thermophilus isolate STH_CIRM_19]
MNTKILDQLEFNKVKDQFTEYLQTEQAQAELRDLVPMTNPERIQNQFTEIQEMSEIFVEHHGFAIGSLRDISEPLRRLEL
DADLNIQELIAIKKVLQASADLSRFYADLENVELIALKRLFEKIEAFPSLQGSLQSINDGGFIEHFASPELQNIRRQLKA
CDDAIRQTLQDILKKSGHMLAENLIASRNGRSVLPVKNTYRNRIAGVVHDISSSGNTVYIEPRAVIQLNEKITQLRADER
HEMARILHELSDQLRPHTAAIANNAWILGHMDFIRGKYLYLHDKKAIIPEISDNQILQLLNVRHPLLINPVANDLRFDED
LTVIVITGPNTGGKTVMLKTLGLAQLMAQSGLPILADKGSRIAIFQEIFADIGDEQSIEQSLSTFSSHMTHIVEILNTAD
SNSLVLVDELGAGTDPQEGASLAMAILEHLRLSQIKTMATTHYPELKAYGIETQHVENASMEFDTATLRPTYRFMQGVPG
RSNAFEIARRLGLNEIIVKEAENLTDTDSDVNRIIEQLEAQTVETQKRLEHIKDVEQENLKFNRAVKKLYNEFSHEYDKE
LEKAQKEIQEMVDTALAESDSILKNLHDKSQLKPHEVIDAKGKLKKLAAQVDLSKNKVLRKAKKEKAARAPRVGDDIIVT
AYGQRGTLTSQAKNGNWEAQVGLIKMSLKADEFTLVRTQAEAQQPKKKQINVVKKAKKTSSDGPRARLDLRGKRYEEAMQ
ELDAFIDQALLNNMSQVEIIHGIGTGVIRDAVTKYLRRHRHVKNFEYAPQSAGGSGCTIATLG

Nucleotide


Download         Length: 2352 bp        

>NTDB_id=1009072 H0503_RS08215 WP_179971436.1 1592172..1594523(+) (mutS/mutS2) [Streptococcus thermophilus isolate STH_CIRM_19]
ATGAACACAAAGATTTTAGACCAATTAGAATTTAACAAGGTCAAAGACCAGTTCACAGAATACCTGCAGACCGAACAGGC
TCAGGCGGAGTTACGTGACTTGGTGCCTATGACCAATCCAGAAAGAATTCAAAACCAATTTACAGAAATCCAAGAAATGT
CTGAGATTTTCGTAGAGCATCATGGCTTTGCCATTGGTAGCTTAAGAGATATTTCTGAGCCCTTGCGTCGCTTGGAACTG
GATGCTGACCTCAACATCCAGGAGCTCATTGCTATCAAGAAGGTCTTGCAAGCTTCAGCTGACCTTAGCCGCTTCTACGC
TGACCTTGAAAATGTTGAACTCATCGCTCTTAAACGTCTTTTTGAAAAGATTGAGGCCTTTCCAAGTCTACAAGGTAGTC
TTCAAAGTATTAATGATGGTGGTTTTATTGAGCATTTTGCTAGTCCTGAGTTGCAAAATATCCGTCGTCAACTTAAGGCT
TGTGATGATGCCATTCGCCAGACCTTGCAAGACATTCTCAAGAAATCTGGGCACATGTTAGCTGAGAACTTAATTGCTAG
TCGTAATGGCCGTTCAGTGCTCCCTGTCAAAAATACCTACCGTAACCGTATTGCGGGGGTTGTTCATGACATCTCAAGCT
CTGGGAACACAGTGTATATCGAGCCACGAGCCGTTATCCAGCTTAACGAAAAAATTACACAATTACGTGCAGACGAGCGC
CATGAGATGGCACGTATCCTACATGAACTGTCTGATCAACTCCGTCCACATACTGCTGCCATCGCTAACAACGCTTGGAT
TTTGGGCCATATGGACTTCATTAGAGGAAAATACCTCTATCTCCATGATAAAAAGGCAATTATTCCAGAGATTAGTGACA
ACCAAATACTCCAACTGCTTAACGTTCGTCACCCTCTTTTAATCAATCCAGTAGCCAACGATTTGCGCTTTGATGAAGAT
CTCACGGTCATTGTCATTACAGGTCCCAATACTGGTGGTAAAACGGTCATGCTTAAAACTCTAGGACTAGCTCAACTAAT
GGCTCAATCTGGTCTGCCAATTTTGGCTGATAAGGGCAGTCGTATAGCCATTTTCCAAGAGATTTTTGCGGATATCGGAG
ACGAACAGTCTATCGAACAGAGCTTGTCAACTTTCTCTAGTCACATGACGCACATTGTCGAGATTTTGAACACTGCCGAC
AGCAATAGCTTGGTCTTGGTCGATGAGCTTGGGGCTGGTACCGACCCTCAGGAAGGGGCTAGTCTAGCCATGGCAATCCT
AGAGCACCTCCGTTTGAGCCAGATTAAGACCATGGCTACTACTCACTATCCTGAGCTTAAGGCCTATGGGATTGAGACAC
AACATGTGGAAAATGCTAGCATGGAGTTTGACACAGCAACTCTAAGACCTACCTATCGCTTTATGCAAGGGGTTCCTGGT
CGCTCTAACGCCTTTGAGATTGCTCGCCGCCTCGGTTTGAATGAGATTATTGTCAAGGAAGCAGAAAACCTCACTGATAC
GGATAGTGATGTCAACCGTATCATCGAGCAACTTGAAGCCCAAACTGTAGAAACACAAAAACGTCTGGAGCACATCAAGG
ACGTTGAGCAAGAGAACCTTAAATTCAACCGTGCGGTCAAGAAACTCTATAATGAATTCTCCCATGAGTACGACAAGGAA
CTCGAAAAGGCTCAAAAAGAAATTCAAGAGATGGTGGATACAGCTTTAGCTGAAAGCGATAGTATTCTCAAAAATCTCCA
TGATAAGAGTCAACTCAAGCCTCATGAAGTTATCGACGCCAAAGGGAAACTTAAGAAACTTGCCGCACAAGTCGACCTTT
CTAAGAACAAGGTTCTTCGTAAAGCCAAGAAAGAAAAGGCTGCGCGTGCCCCTCGTGTCGGTGATGATATCATCGTTACT
GCCTATGGGCAACGTGGTACGCTCACCAGTCAAGCCAAAAATGGTAACTGGGAAGCTCAAGTGGGTCTCATCAAGATGAG
CCTAAAGGCAGACGAATTCACTCTGGTTCGTACCCAAGCAGAAGCACAACAACCCAAGAAAAAACAAATTAATGTGGTTA
AAAAAGCCAAGAAGACATCTTCTGATGGGCCTCGTGCCCGTCTAGACCTTCGTGGGAAACGTTACGAAGAAGCCATGCAA
GAGCTCGATGCCTTTATTGACCAAGCTCTACTTAACAACATGAGTCAGGTGGAAATCATCCACGGTATTGGTACCGGTGT
CATCCGAGATGCTGTAACCAAATATCTCCGCCGTCATCGCCATGTTAAAAATTTTGAATATGCCCCACAAAGTGCTGGTG
GTTCCGGATGTACCATCGCAACCTTGGGTTAA

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-505)

Smr domain (Smr)

(708-782)

MutS2 and Smr-associated SH3 domain (MSSS)

(633-672)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

39.295

100

0.398