Detailed information NTG1005701

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: FGL14_RS09350
• Genome accession: NZ_LR594045
• Coordinates: 1841041..1841823 (-)
• Length: 260 a.a.
• NCBI ID: WP_003053880.1
• Uniprot ID: A0A9X9SKT8
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC9413
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1836041..1846823

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL14_RS09320 (NCTC9413_01928)	-	1836687..1837280 (-)	594	WP_274047907.1	helix-turn-helix transcriptional regulator	-
FGL14_RS09325 (NCTC9413_01929)	-	1837511..1837810 (-)	300	WP_065957237.1	rhodanese-like domain-containing protein	-
FGL14_RS09330 (NCTC9413_01930)	-	1837803..1839455 (-)	1653	WP_003059881.1	FAD-dependent oxidoreductase	-
FGL14_RS09335 (NCTC9413_01931)	-	1839473..1839811 (-)	339	WP_065957236.1	rhodanese-like domain-containing protein	-
FGL14_RS09340 (NCTC9413_01932)	-	1840025..1840285 (+)	261	WP_065957235.1	metal-sensitive transcriptional regulator	-
FGL14_RS09345 (NCTC9413_01933)	-	1840352..1840900 (-)	549	WP_046159404.1	isochorismatase family cysteine hydrolase	-
FGL14_RS09350 (NCTC9413_01934)	codY	1841041..1841823 (-)	783	WP_003053880.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
FGL14_RS09355 (NCTC9413_01935)	-	1842088..1843302 (-)	1215	WP_065957234.1	pyridoxal phosphate-dependent aminotransferase	-
FGL14_RS09360 (NCTC9413_01936)	-	1843639..1844091 (+)	453	WP_003052566.1	universal stress protein	-
FGL14_RS09365 (NCTC9413_01937)	-	1844254..1845642 (-)	1389	WP_003052568.1	Cof-type HAD-IIB family hydrolase	-
FGL14_RS09370 (NCTC9413_01938)	-	1845715..1846680 (+)	966	WP_138084022.1	asparaginase	-

Sequence

Protein

• Length: 260 a.a.
• Molecular weight: 28748.89 Da
• Isoelectric Point: 4.4678

>NTDB_id=1005701 FGL14_RS09350 WP_003053880.1 1841041..1841823(-) (codY) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC9413]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVESELTIFPVESKDIYPDGLTTIAPIYGGGMRLGSLIIWRNDNEFSDEDLILVEISSTVVGIQLLN
LQTENLEETIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFDKLKEF

Nucleotide

• Length: 783 bp

>NTDB_id=1005701 FGL14_RS09350 WP_003053880.1 1841041..1841823(-) (codY) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC9413]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATTACGTCTATTCTACAGCGCTCTGTAGATAGCTTGGAGACAGAACTCCC
ATATAATACGATGGCGTCTCGCTTGGCAGATATTATTGACTGTAATGCCTGCATTATCAATGGCGGAGGAACCCTACTTG
GTTATGCCATGAAATATAAAACCAACACAGACCGTGTTGAGGAATTTTTTGAAGCTAAGCAATTTCCAGATACTTATGTC
AAAGCAGCTAGCCGTGTCTACGACACTGAGGCCAATCTTTCAGTGGAAAGTGAATTAACCATTTTTCCTGTGGAATCGAA
AGACATCTATCCAGATGGTTTGACAACAATTGCACCGATTTATGGTGGAGGTATGCGTCTAGGATCTCTTATCATTTGGC
GCAACGATAATGAGTTTAGTGATGAGGACCTCATCTTGGTTGAAATTTCAAGCACGGTTGTTGGGATTCAGTTGTTAAAC
CTTCAAACAGAAAACCTGGAAGAAACGATCCGCAAGCAAACTGCTGTCAACATGGCTATTAACACCCTATCTTATTCAGA
AATGAAGGCTGTTGCAGCTATTCTTGGTGAATTGGATGGTAACGAAGGGCGTTTAACAGCTTCTGTCATTGCTGACCGTA
TTGGCATTACACGATCTGTGATCGTCAATGCCCTTCGTAAATTGGAAAGTGCTGGTATTATTGAAAGTCGCTCTCTCGGC
ATGAAGGGAACCTACCTCAAAGTTATTAATGAGGGTATTTTTGATAAATTGAAAGAATTTTAA

Domains

Predicted by InterProScan.

• CodY helix-turn-helix domain (HTH_CodY) (202-260)

• CodY GAF-like domain (CodY) (3-182)

3D structure

• AlphaFold DB: A0A9X9SKT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	66.537	98.846	0.658
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	95	0.504