Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   FGL05_RS01260 Genome accession   NZ_LR594044
Coordinates   252486..254822 (+) Length   778 a.a.
NCBI ID   WP_020917440.1    Uniprot ID   A0AB33ANT7
Organism   Streptococcus lutetiensis strain NCTC8796     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 247486..259822
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL05_RS01240 (NCTC8796_00264) lepB 249888..250481 (-) 594 WP_111712992.1 signal peptidase I -
  FGL05_RS01245 (NCTC8796_00265) rnhC 250498..251397 (-) 900 WP_111712991.1 ribonuclease HIII -
  FGL05_RS01250 (NCTC8796_00266) zapA 251517..251825 (+) 309 WP_020917442.1 cell division protein ZapA -
  FGL05_RS01255 (NCTC8796_00267) - 251829..252377 (+) 549 WP_058814226.1 CvpA family protein -
  FGL05_RS01260 (NCTC8796_00268) mutS/mutS2 252486..254822 (+) 2337 WP_020917440.1 endonuclease MutS2 Machinery gene
  FGL05_RS01265 (NCTC8796_00269) nadA 254912..255832 (-) 921 WP_020917439.1 quinolinate synthase NadA -
  FGL05_RS01270 (NCTC8796_00270) - 256167..257471 (+) 1305 WP_111712990.1 L-aspartate oxidase -
  FGL05_RS01275 (NCTC8796_00271) nadC 257500..258360 (+) 861 WP_061408586.1 carboxylating nicotinate-nucleotide diphosphorylase -
  FGL05_RS01280 (NCTC8796_00272) - 258431..258928 (-) 498 WP_043895118.1 phosphatase PAP2 family protein -
  FGL05_RS01285 (NCTC8796_00273) trxA 259171..259485 (+) 315 WP_020917435.1 thioredoxin -

Sequence

Protein


Download         Length: 778 a.a.        Molecular weight: 87631.01 Da        Isoelectric Point: 6.4218

>NTDB_id=1005530 FGL05_RS01260 WP_020917440.1 252486..254822(+) (mutS/mutS2) [Streptococcus lutetiensis strain NCTC8796]
MNNRILEQLEFDKVKQLFAGYLQTEQGQEELRQLSPMTESDRISRSFDEMSDMEQIFIEQHGFGLGSLRDISESMRRLEL
DADVNVSEIIDIKKILQVSAEVKHFYNDLENVNLTALNTLFEKIELLPSLQGSLQAINDGGFIENFASHELDRIRRQINH
DESRVRQVLQDILKKQADHLTETLIASRNGRAVLPVKNSYRNRISGVVHDISASGSTVYIEPRAVVQLNEEITQLRADER
HEMARILRELSNMLRPHTNIIRNNAWVLGHLDFVHAKFLFMQENKAVVPQLSTDKTVQLLQARHPLLTNPVANDLHFLDE
LTVIVITGPNTGGKTVMLKTLGLAQLMAQSGLPILADKGSKVAVFNEIFADIGDEQSIEQSLSTFSSHMTNIVDILAAAD
KDSLVLVDELGAGTDPQEGASLAISILEHLRLMQVKTMATTHYPELKAYGIETEFVENASMEFDTETLSPTYHFMQGVPG
RSNAFEIARRLGLAEVIVNEAERLMDSDTDVNRIIERLEEQTHESRKRLDHIKEVEQDNLKFNRAVKKLYNEFSHAKDKE
LEKASDKAQEIVDKAMAESEEILKNLHHKAGLKPHEVIEAKSQLKKLAPEVDLSKNKVLKKAKKLRAPRVGDDIIVTAYG
QRGTLINQTKNGKWEVQVGLIKMMLKEDEFSLVKVQEEAQKPKKKQVHVVKKSKKSAGPRARLDLRGKRYEEAMQELDEF
IDQALLNNIAQVDIIHGIGTGVIREGVTKYLSRNKHVKSFGYAPQNAGGSGCTIANLG

Nucleotide


Download         Length: 2337 bp        

>NTDB_id=1005530 FGL05_RS01260 WP_020917440.1 252486..254822(+) (mutS/mutS2) [Streptococcus lutetiensis strain NCTC8796]
ATGAATAACAGAATTTTAGAACAGTTAGAATTTGATAAGGTCAAGCAACTTTTTGCTGGCTATTTACAAACTGAGCAAGG
GCAGGAGGAATTACGTCAACTTTCTCCAATGACTGAATCAGATCGTATCTCACGTTCATTTGATGAAATGTCTGATATGG
AGCAGATTTTCATTGAGCAACACGGATTTGGTCTTGGCAGTTTGCGTGATATTTCTGAAAGTATGCGTCGCTTAGAATTG
GATGCTGATGTTAACGTTTCAGAGATTATTGATATTAAAAAAATCTTGCAAGTATCAGCAGAAGTTAAGCATTTCTATAA
CGATTTGGAAAATGTTAACTTGACGGCTTTAAATACTCTTTTTGAGAAAATTGAGCTTTTGCCAAGTCTGCAAGGAAGTT
TACAAGCCATTAACGATGGTGGATTTATTGAGAATTTTGCAAGTCATGAATTAGACCGTATTCGTCGTCAAATCAATCAT
GATGAAAGCAGAGTTCGTCAAGTCTTGCAGGATATCTTGAAAAAGCAAGCTGACCATTTGACAGAGACTTTGATTGCTAG
TCGTAATGGTCGAGCAGTTTTACCTGTGAAAAATAGCTACCGCAACCGTATCTCAGGGGTTGTGCATGATATTTCAGCAT
CAGGAAGCACCGTTTATATTGAGCCACGTGCAGTGGTGCAACTAAATGAAGAAATCACACAATTACGCGCAGATGAACGC
CATGAAATGGCTCGTATTTTACGCGAATTGTCAAATATGCTTCGCCCTCATACTAATATTATTCGAAATAATGCTTGGGT
TTTGGGACATTTGGATTTTGTGCATGCAAAATTTCTCTTCATGCAAGAAAACAAAGCAGTTGTCCCACAGTTATCCACAG
ATAAGACTGTGCAACTCTTGCAAGCTCGTCACCCGCTGTTGACAAATCCAGTCGCAAATGACTTGCATTTCTTAGATGAA
TTGACAGTTATCGTTATCACTGGTCCAAATACCGGTGGTAAAACCGTCATGTTGAAAACTTTGGGATTGGCACAATTAAT
GGCGCAATCTGGTCTACCAATTCTTGCTGATAAAGGTAGTAAAGTGGCTGTTTTTAATGAGATTTTTGCTGACATCGGTG
ATGAACAATCTATCGAGCAAAGCCTGTCAACATTCTCAAGCCATATGACAAATATTGTGGATATCTTGGCAGCTGCTGAT
AAAGATAGCTTGGTCCTTGTGGATGAATTGGGGGCAGGAACTGACCCACAAGAAGGGGCAAGTCTTGCCATTTCTATCTT
GGAACATTTGCGTTTGATGCAAGTCAAAACCATGGCGACAACCCATTATCCTGAGTTAAAAGCTTACGGTATCGAGACAG
AGTTTGTTGAAAATGCCAGCATGGAATTTGACACAGAGACTTTGAGCCCGACTTATCATTTCATGCAAGGTGTGCCAGGA
CGCTCAAATGCTTTTGAAATCGCTCGTCGATTAGGTCTTGCAGAAGTGATTGTCAATGAAGCAGAGCGTTTGATGGATTC
TGATACGGATGTTAACCGCATCATCGAACGTTTGGAAGAGCAAACGCACGAAAGCCGCAAACGTCTTGACCACATCAAAG
AAGTGGAACAAGATAACCTCAAATTCAACCGTGCAGTCAAGAAACTTTATAACGAATTCTCACACGCCAAAGATAAAGAA
CTTGAAAAAGCTTCTGACAAGGCACAAGAAATTGTGGATAAAGCCATGGCTGAAAGTGAAGAAATCCTCAAAAATCTTCA
TCACAAAGCTGGCCTTAAACCGCACGAAGTGATCGAAGCTAAAAGCCAGTTGAAAAAATTAGCGCCTGAAGTTGATTTAT
CGAAAAATAAAGTTCTTAAGAAAGCCAAGAAATTGCGTGCACCGCGCGTGGGTGATGATATTATCGTCACAGCTTATGGT
CAACGCGGAACCTTGATTAACCAAACGAAAAACGGTAAATGGGAAGTGCAAGTTGGTCTCATTAAGATGATGCTTAAAGA
AGACGAATTTAGCCTTGTCAAAGTTCAAGAAGAAGCGCAAAAACCTAAGAAAAAACAAGTCCATGTGGTTAAGAAAAGCA
AGAAATCTGCTGGACCACGTGCCCGACTTGACCTTCGTGGTAAACGTTACGAAGAAGCCATGCAAGAATTGGATGAATTT
ATCGATCAAGCCTTGCTCAATAACATAGCTCAAGTTGATATCATTCACGGTATCGGAACAGGTGTTATCCGTGAAGGGGT
CACAAAATACCTTAGCCGCAACAAACATGTCAAATCATTCGGCTACGCCCCACAAAATGCAGGTGGTAGCGGTTGTACTA
TTGCAAATCTAGGGTAA

Domains

Predicted by InterProScan.

MutS2 and Smr-associated SH3 domain (MSSS)

(630-669)

Smr domain (Smr)

(703-776)

MutS domain V (MutS_V)

(324-505)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AB33ANT7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

41.646

100

0.423