Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   E0F39_RS08345 Genome accession   NZ_LR216060
Coordinates   1555418..1556206 (-) Length   262 a.a.
NCBI ID   WP_000940734.1    Uniprot ID   Q8DP01
Organism   Streptococcus pneumoniae strain GPSC47 substr. ST315     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1550418..1561206
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F39_RS08320 (SAMEA3713867_01580) - 1551404..1551916 (-) 513 WP_001049323.1 adenine phosphoribosyltransferase -
  E0F39_RS08325 (SAMEA3713867_01581) - 1552004..1552762 (-) 759 WP_001287230.1 class I SAM-dependent methyltransferase -
  E0F39_RS12100 - 1552970..1553116 (+) 147 WP_001826606.1 hypothetical protein -
  E0F39_RS08330 (SAMEA3713867_01582) - 1553263..1554393 (-) 1131 WP_000229961.1 ABC transporter ATP-binding protein -
  E0F39_RS08340 (SAMEA3713867_01584) - 1554843..1555418 (-) 576 WP_000158722.1 cysteine hydrolase family protein -
  E0F39_RS08345 (SAMEA3713867_01585) codY 1555418..1556206 (-) 789 WP_000940734.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  E0F39_RS08355 (SAMEA3713867_01586) - 1556470..1558029 (-) 1560 WP_050128452.1 DEAD/DEAH box helicase -
  E0F39_RS08360 (SAMEA3713867_01587) - 1558228..1559454 (-) 1227 WP_000841592.1 OFA family MFS transporter -
  E0F39_RS08365 (SAMEA3713867_01588) - 1559647..1560963 (+) 1317 WP_000958923.1 FAD-containing oxidoreductase -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 29756.11 Da        Isoelectric Point: 5.4646

>NTDB_id=1003871 E0F39_RS08345 WP_000940734.1 1555418..1556206(-) (codY) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNACIINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYV
QGANMIYETEANLPVEHDMSIFPVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLISDIFEEVKKRDY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=1003871 E0F39_RS08345 WP_000940734.1 1555418..1556206(-) (codY) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
ATGGCACATTTATTAGAAAAAACTAGAAAAATTACATCAATTTTGAAACGCTCAGAGGAGCAGTTGCAGGATGAGCTCCC
TTACAACGCTATTACGCGTCAGTTAGCGGATATTATTCATTGCAATGCCTGCATTATCAATAGTAAGGGACGTCTGCTTG
GCTATTTTATGCGTTATAAAACAAATACAGATCGCGTAGAGCAATTCTTCCAAACTAAGATTTTCCCAGATGACTACGTT
CAAGGGGCTAATATGATTTACGAAACAGAAGCAAACTTGCCTGTTGAGCATGATATGAGTATTTTCCCTGTTGAGAGTAG
AGATGATTTTCCAGATGGCTTGACGACTATTGCACCGATTCATGTATCGGGGATTCGCCTTGGTTCTTTGATTATTTGGC
GTAATGATAAAAAATTCGAAGATGAGGACTTGGTTCTTGTTGAGATTGCCAGTACCGTTGTTGGGATTCAGCTTCTTAAC
TTCCAACGTGAAGAAGATGAGAAAAATATTCGTCGTCGTACTGCTGTCACCATGGCGGTCAATACCCTTTCTTACTCCGA
ACTCCGTGCTGTTTCAGCAATTTTAGGGGAATTAAATGGAAATGAAGGGCAGTTGACTGCGTCAGTGATTGCAGATCGTA
TCGGAATCACTCGCTCTGTGATTGTCAATGCTCTTCGTAAACTTGAGTCTGCGGGGATTATTGAAAGTCGCTCACTTGGA
ATGAAGGGAACCTATCTTAAGGTCTTGATTTCAGATATTTTTGAAGAAGTGAAGAAAAGAGATTACTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-258)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DP01

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

62.595

100

0.626
  codY Bacillus subtilis subsp. subtilis str. 168

48.374

93.893

0.454

Multiple sequence alignment