Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   E0F32_RS07720 Genome accession   NZ_LR216050
Coordinates   1441590..1442378 (-) Length   262 a.a.
NCBI ID   WP_000940733.1    Uniprot ID   C1CSK2
Organism   Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1436590..1447378
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F32_RS07695 (SAMEA3431333_01448) - 1437577..1438089 (-) 513 WP_001049323.1 adenine phosphoribosyltransferase -
  E0F32_RS07700 (SAMEA3431333_01449) - 1438176..1438934 (-) 759 WP_001287233.1 class I SAM-dependent methyltransferase -
  E0F32_RS11380 - 1439142..1439312 (+) 171 WP_000403103.1 hypothetical protein -
  E0F32_RS07705 (SAMEA3431333_01450) - 1439435..1440565 (-) 1131 WP_000229959.1 ABC transporter ATP-binding protein -
  E0F32_RS07715 (SAMEA3431333_01452) - 1441015..1441590 (-) 576 WP_024477852.1 cysteine hydrolase family protein -
  E0F32_RS07720 (SAMEA3431333_01453) codY 1441590..1442378 (-) 789 WP_000940733.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  E0F32_RS07730 (SAMEA3431333_01454) - 1442643..1444217 (-) 1575 WP_000671107.1 DEAD/DEAH box helicase -
  E0F32_RS07735 (SAMEA3431333_01455) - 1444416..1445642 (-) 1227 WP_000841572.1 OFA family MFS transporter -
  E0F32_RS07740 (SAMEA3431333_01456) - 1445835..1447151 (+) 1317 WP_000958925.1 FAD-containing oxidoreductase -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 29756.15 Da        Isoelectric Point: 5.7806

>NTDB_id=1003753 E0F32_RS07720 WP_000940733.1 1441590..1442378(-) (codY) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNACIINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYV
QGANMIYETEANLPVEHDMSIFPVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLISDIFEEVKKRDY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=1003753 E0F32_RS07720 WP_000940733.1 1441590..1442378(-) (codY) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
ATGGCACATTTATTAGAAAAAACTAGAAAAATTACATCAATTTTGAAACGCTCAGAGGAGCAGTTGCAGGATGAGCTCCC
TTACAACGCTATTACGCGTCAGTTAGCGGATATTATTCATTGCAATGCCTGCATTATCAATAGTAAGGGACGTCTGCTTG
GCTATTTTATGCGTTATAAAACAAATACAGATCGCGTAGAGCAATTCTTCCAAACTAAGATTTTCCCAGATGACTACGTT
CAAGGGGCTAATATGATTTACGAAACAGAAGCAAACTTGCCTGTTGAGCATGATATGAGTATTTTCCCTGTTGAGAGTAG
AGATGATTTTCCAGATGGCTTGACGACTATTGCACCGATTCATGTATCGGGGATTCGCCTTGGTTCTTTGATTATTTGGC
GTAATGATAAAAAATTCGAAGATGAGGACTTGGTTCTTGTTGAGATTGCCAGTACCGTTGTTGGGATTCAGCTTCTTAAC
TTCCAACGTGAAGAAGATGAGAAAAATATTCGTCGTCGTACTGCTGTCACCATGGCGGTCAATACCCTTTCTTACTCCGA
ACTCCGTGCTGTTTCAGCAATTTTAGGGGAATTAAATGGAAATGAAGGGAAGTTGACTGCGTCAGTGATTGCAGATCGTA
TCGGAATCACTCGCTCTGTGATTGTCAATGCTCTTCGTAAACTTGAGTCTGCGGGGATTATTGAAAGTCGCTCACTTGGA
ATGAAGGGAACCTATCTTAAGGTCTTGATTTCAGATATTTTTGAAGAAGTGAAGAAAAGAGATTACTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-258)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C1CSK2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

62.595

100

0.626
  codY Bacillus subtilis subsp. subtilis str. 168

48.374

93.893

0.454

Multiple sequence alignment