Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   EL107_RS09405 Genome accession   NZ_LR134314
Coordinates   47480..48346 (+) Length   288 a.a.
NCBI ID   WP_011184363.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8302     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 42480..53346
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL107_RS00210 (NCTC8302_00042) - 42521..43396 (+) 876 WP_002985236.1 F0F1 ATP synthase subunit gamma -
  EL107_RS00215 (NCTC8302_00043) atpD 43558..44964 (+) 1407 WP_011017611.1 F0F1 ATP synthase subunit beta -
  EL107_RS00220 (NCTC8302_00044) - 44977..45393 (+) 417 WP_002985233.1 F0F1 ATP synthase subunit epsilon -
  EL107_RS00225 (NCTC8302_00045) - 45680..45916 (+) 237 WP_280529076.1 DUF1146 family protein -
  EL107_RS00230 (NCTC8302_00046) murA 45981..47252 (+) 1272 WP_002994428.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  EL107_RS00235 (NCTC8302_00047) - 47256..47444 (+) 189 WP_011017613.1 DNA-directed RNA polymerase subunit beta -
  EL107_RS09405 (NCTC8302_00048) endA 47480..48346 (+) 867 WP_011184363.1 DNA/RNA non-specific endonuclease Machinery gene
  EL107_RS00245 (NCTC8302_00050) pheS 48629..49672 (+) 1044 WP_003057440.1 phenylalanine--tRNA ligase subunit alpha -
  EL107_RS00250 (NCTC8302_00051) pheT 49882..52287 (+) 2406 WP_023078221.1 phenylalanine--tRNA ligase subunit beta -
  EL107_RS00255 (NCTC8302_00052) - 52399..52776 (+) 378 WP_021340346.1 OsmC family protein -
  EL107_RS00260 (NCTC8302_00053) - 52769..53155 (+) 387 WP_002990406.1 YbgA family protein -

Sequence

Protein


Download         Length: 288 a.a.        Molecular weight: 32111.62 Da        Isoelectric Point: 10.4010

>NTDB_id=1001228 EL107_RS09405 WP_011184363.1 47480..48346(+) (endA) [Streptococcus pyogenes strain NCTC8302]
MLAKKKRKRVLNSFLLILLVLGSNCLAKSDFIASNHPIKQLYQTLVGEKKKSLLTHNNLPADVPTEALAASVLTPSIKKQ
LGPDVQWNGAGAYIINRNKTDLNAKVASLPYANNETKWVQEQKVPKRANALLTKSTRQYRNRYQTDNAYRNFKPAGWHRL
HRLKGSYDHAVDRGHLLGYALVGGLKGLDASTGNPDNIATQLSWANQANKPYSTGQNYYEGLVCRALDKGHRVRYRVTLL
YDGDNLLASGSHLEAKSSDDSLTFNVFVPNVQPGLTVDYRTRQIAINL

Nucleotide


Download         Length: 867 bp        

>NTDB_id=1001228 EL107_RS09405 WP_011184363.1 47480..48346(+) (endA) [Streptococcus pyogenes strain NCTC8302]
ATGTTAGCAAAGAAAAAACGAAAAAGGGTGCTTAATTCCTTCTTATTGATTTTGTTAGTGTTGGGGTCTAACTGCCTTGC
TAAGAGTGATTTCATAGCTAGCAATCACCCTATCAAGCAACTTTATCAGACTCTTGTTGGGGAGAAGAAAAAATCATTAC
TCACACATAATAATTTGCCCGCTGATGTTCCCACAGAAGCTCTGGCGGCATCGGTATTAACACCATCAATCAAAAAGCAA
CTAGGTCCAGATGTTCAGTGGAATGGAGCAGGCGCCTATATTATCAACAGGAACAAAACAGATTTAAATGCTAAGGTAGC
CAGTCTGCCCTATGCCAACAATGAAACCAAATGGGTGCAAGAGCAAAAGGTTCCTAAAAGAGCTAATGCCTTACTTACTA
AGTCGACACGACAGTATCGAAATCGCTATCAAACGGACAATGCTTATCGTAACTTTAAGCCAGCAGGTTGGCACCGATTG
CACCGCTTAAAAGGAAGTTATGATCACGCGGTTGATAGAGGGCATTTGCTAGGTTATGCTTTAGTTGGTGGACTGAAAGG
TTTAGATGCTTCTACCGGTAATCCTGATAATATTGCCACTCAACTAAGTTGGGCTAATCAAGCAAATAAACCCTACTCGA
CAGGTCAGAATTACTATGAAGGTTTAGTATGTCGTGCTTTGGATAAGGGGCATCGCGTCCGCTACCGTGTCACCCTACTT
TATGATGGTGATAATCTACTAGCCAGCGGTAGCCATTTGGAGGCTAAATCCTCTGATGACAGCTTGACTTTTAACGTGTT
TGTTCCAAATGTCCAACCAGGATTGACCGTTGACTATAGGACGAGACAAATAGCTATCAATCTCTAA

Domains

Predicted by InterProScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(111-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

57.806

82.292

0.476
  endA Streptococcus pneumoniae D39

57.806

82.292

0.476
  endA Streptococcus pneumoniae R6

57.806

82.292

0.476
  endA Streptococcus pneumoniae TIGR4

57.806

82.292

0.476