Detailed information of T4CP

T4CP

• ID: 200
• GenBank: AAL59453
• Name: Orf53_pAD1
• UniProt ID: Q8VT41
• Length: 747 a.a.
• PDB ID: _
• Note: conjugative coupling factor TraD, SXT/TOL subfamily; TIGR03743

Protein sequence

• Length: 747 a.a.
• Molecular weight: 85562.94 Da
• Isoelectric Point: 6.3682

>AAL59453.1 unknown (plasmid) [Enterococcus faecalis]
MFNNGLLQPKKPPIGQEQQKMTRYHQLRLVFGLVGVLLYPFAILGSIPLLIGLAVDKRDKAANVFDMDYE
SFLKRNSIVFLSFSAVLFVINAFAFILWIPRGYLSAYLLFPLNLLHTALRFNWETIVALLIGSSGMGAIF
LAFSSFVAKRKVISKEDERKKITESKAYKDREKNKFKESQRFTDEQEEAYEEAVETVDIDKYKELSNQLL
LGTSEFGLPYIINFSEFNQHVLVPATTGSGKTTLLQLLVQHAVKFNFPVILIDGKGARDTLESMREIAKF
YDKEVHAFTDDGDMRYNPVEHGNDISIRDKLVSLAETESVFYSGAAKALLQVTIQLLDEFKGAKVTLSGD
TRTTETVERSLPFVQRFLLPRNVLHLFADAILQNNPKLFEIEVEKKIQQPKKKSAKERSEILPDSDLDKE
EKEEDSQIRNSKFRNISQLGIAQKETETVVLNPETLDLDSYYLLLKRNLRYLPTDKETGENIKQKLFERL
FVRYEHKDSPFYLYATSEALQTNINMLLDSELGKLFDTKNAKNVLDVQEIVNQRKLVYVSFNGLIYKEYI
RTLAQMLVGDVNYFASEMYRKNVKREVLVIFDEPASYLNETFIDMVNKGRGAGVYGIFTPQTMADIAKLG
DKLMEQLVGNVNTLFIGKTNEKGEAEYWSETMGTYQDIDVTSVTEQEDGYSDVGKSDWSGDRGTKRNVDR
FKISPNKIKELRTGEFIIYRTAENVNLPPQKVYVRNALEWLQKSNSK

Protein domains

Predicted by InterproScan

• TraM recognition site of TraD and TraG (TraG-D_C) (587-686)

• Helicase HerA, central domain (DUF87) (217-408)

Protein structure

• AlphaFold DB: Q8VT41

Reference

[1] Francia MV et al. (2004) A classification scheme for mobilization regions of bacterial plasmids. FEMS Microbiol Rev. 28(1):79-100. [PMID:14975531]
[2] Francia MV et al. (2002) Transfer origins in the conjugative Enterococcus faecalis plasmids pAD1 and pAM373: identification of the pAD1 nic site, a specific relaxase and a possible TraG-like protein. Mol Microbiol. 45(2):375-95. [PMID:12123451]