Detailed information of relaxase

Relaxase

• ID: 499
• GenBank: YP_006792604
• Name: TraI_pAA-EA11
• UniProt ID: A0A0E0Y6S8
• Family: Other
• PDB ID: _
• Length: 1237 a.a.
• Note: putative relaxase

Protein sequence

• Length: 1237 a.a.
• Molecular weight: 134489.20 Da
• Isoelectric Point: 5.9884

>YP_006792604.1 conjugal transfer nickase/helicase TraI (plasmid) [Escherichia coli O104:H4 str. 2011C-3493]
MAELVMMAREQGREVQIIAADRRSQMNLKQDERLSGELITGRRQLQDGMTFTPGSTVIVDQGEKLSLKET
LTLLDGAARHNVQVLITDSGQRTGTGSALMAMKDAGVNTYRWQGGEQRPATIISEPDRNVRYARLAGDFA
ASVKAGEESVAQVSGVREQAILTQAIRSELKTQGVLGHPEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQ
WNPETRSHDRYVIDRVTAQSHSLTLRDAQGETQVVRISSLDSSWSLFRPEKMPVADGERLRVTGKTPGLR
VSGGDRLQVASVSEDAMTVVVPGRAEPATLPVADSPFTALKLENGWVETPGHSVSDSATVFASVTQMAMD
NATLNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETSLETAISLQKAGLHTPAQQAI
HLALPVLESKNLAFSMVDLLTEAKSFAAEGTGFTELGGEINAQIKRGDLLYVDVAKGYGTGLLVSRASYE
AEKSILRHILEGKEAVTPLMERVPGELMETLTSGQRAATRMILEASDRFTVVQGYAGVGKTTQFRAVMSA
VNMLPASERPRVVGLGPTHRAVGEMRSAGVDAQTLASFLHDTQLQQRSGETPDFSNTLFLLDESSMVGNT
DMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAADVAIMKEIVRQTPELREAVYSLINRDV
ERALSGLESVKPSQVPRLEGAWAPEHSVTEFSHSQEAKLAEAQQKAMLKGEAFPDVPMTLYEAIVRDYTG
RTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMVPVLNTANIRDGELRRLSTWEKNPDALA
LVDSVYHRIAGISKDDGLITLQDAEGNTRLISPREAVAEGVTLYTPDKIRVGTGDRMRFTKSDRERGYVA
NSVWTVTAVSGDSVTLSDGQQTRVIRPGQERAEQHIDLAYAITAHGAQGASETFAIALEGTEGNRKQMAG
FESAYVALSRMKQHVQVYTDNRQGWTDAINNAVQKGTAHDVFEPKPDREVMNAQRLFSTARELRDVAAGR
AVLRQAGLSGGDSPARFIAPGRKYPQPYVALPAFDRNGRSAGIWLNPLTTDDGNGLRGFSGEGRVKGSED
AQFVALQGSRNGESLLADNMQDGVRIARDNPDSGVVVRIAGEGRPWNPGAITGGRVWGDIPDSSVQPGAG
NGEPVTAEVLAQRQAEEAIRRETERRADEIVRKMAENKPDLPDGKTE

Protein domains

Predicted by InterproScan

• single-stranded DNA binding TraI N-terminal subdomain (ssDNA_TraI_N) (127-178)

• DNA helicase TraI (TraI_C) (986-1109)

• DNA relaxase TraI 2B/2B-like domain (TraI_2B) (185-264)

• AAA domain (AAA_30) (520-708)

Protein structure

• AlphaFold DB: A0A0E0Y6S8