Detailed information of relaxase

Relaxase

• ID: 43
• GenBank: AAR31100
• Name: TraI_pJP4
• UniProt ID: Q6UP38
• Family: MOB_P
• PDB ID: _
• Length: 746 a.a.
• Note: conjugal transfer relaxase TraI; Provisional

Protein sequence

• Length: 746 a.a.
• Molecular weight: 82038.71 Da
• Isoelectric Point: 10.7900

>AAR31100.1 relaxosome stabilization protein (plasmid) [Cupriavidus pinatubonensis JMP134]
MIAKHVPMRSLGKSDFAGLANYITDAQSKDHRLGHVQATNCEAGSIQDAITEVLATQHTNTRAKGDKTYH
LIVSFRAGEQPSADTLRAIEERICVGLGYGEHQRISAVHNDTDNLHIHIAINKIHPTRHTMHEPYYPHRA
LAELCTALERDYGLERDNHEPRKRGAEGRAADMERHAGVESLVGWIKRECLDEIKGAQSWQELHQVMRDN
GMELRVRANGLVFEAGDGTMVKASTVARDLSKPSLEARLGPFEASPERQAQTTAKRQYRKDPIRLRVNTV
ELYAKYKAEQQSLTTARAQALERARHRKDRLIEAAKRSNRLRRATIKVVGEGRANKKLLYAQASKALRSE
LQAINKQFQQERTALYAEHSRRTWADWLKKEAQHGGADALAALRAREAAQGLKGNTIRGEGQAKPGHAPA
VDNITKKGTIIFRAGMSAVRDDGDRLQVSREATREGLQEALRLAMQRYGNRITVNGTVEFKAQMIRAAVD
SQLPITFTDPALESRRQALLNKENTHERTERPEHRGRTGRGAGGPGQRPAADQHATGAAAVARAGDGRPA
AGRGDRADAGLHAATVHRKPDVGRLGRKPPPQSQHRLRALSELGVVRIAGGSEVLLPRDVPRHVEQQGTQ
PDHALRRGISRPGTGVGQTPPGVAAADKYIAEREAKRLKGFDIPKHSRYTAGDGALTFQGTRTIEGQALA
LLKRGDEVMVMPIDQATARRLTRIAVGDAVSITAKGSIKTSKGRSR

Protein domains

Predicted by InterproScan

• Large polyvalent protein-associated domain 7 (LPD7) (422-508)

• Relaxase/Mobilisation nuclease domain (Relaxase) (12-251)

Protein structure

• AlphaFold DB: Q6UP38

Reference

[1] Shintani M et al. (2010) The behavior and significance of degradative plasmids belonging to Inc groups in Pseudomonas within natural environments and microcosms. Microbes Environ. 25(4):253-65. [PMID:21576880]
[2] Trefault N et al. (2004) Genetic organization of the catabolic plasmid pJP4 from Ralstonia eutropha JMP134 (pJP4) reveals mechanisms of adaptation to chloroaromatic pollutants and evolution of specialized chloroaromatic degradation pathways. Environ Microbiol. 6(7):655-68. [PMID:15186344]