Detailed information of relaxase

Relaxase

• ID: 38
• GenBank: AFJ38144
• Name: TraI_BRA100
• UniProt ID: I2ALH0
• Family: MOB_P
• PDB ID: _
• Length: 746 a.a.
• Note: relaxase

Protein sequence

• Length: 746 a.a.
• Molecular weight: 82038.71 Da
• Isoelectric Point: 10.7900

>AFJ38144.1 TraI (plasmid) [Mycobacteroides abscessus subsp. bolletii F1725]
MIAKHVPMRSLGKSDFAGLANYITDAQSKDHRLGHVQATNCEAGSIQDAITEVLATQHTNTRAKGDKTYH
LIVSFRAGEQPSADTLRAIEERICVGLGYGEHQRISAVHNDTDNLHIHIAINKIHPTRHTMHEPYYPHRA
LAELCTALERDYGLERDNHEPRKRGAEGRAADMERHAGVESLVGWIKRECLDEIKGAQSWQELHQVMRDN
GMELRVRANGLVFEAGDGTMVKASTVARDLSKPSLEARLGPFEASPERQAQTTAKRQYRKDPIRLRVNTV
ELYAKYKAEQQSLTTARAQALERARHRKDRLIEAAKRSNRLRRATIKVVGEGRANKKLLYAQASKALRSE
LQAINKQFQQERTALYAEHSRRTWADWLKKEAQHGGADALAALRAREAAQGLKGNTIRGEGQAKPGHAPA
VDNITKKGTIIFRAGMSAVRDDGDRLQVSREATREGLQEALRLAMQRYGNRITVNGTVEFKAQMIRAAVD
SQLPITFTDPALESRRQALLNKENTHERTERPEHRGRTGRGAGGPGQRPAADQHATGAAAVARAGDGRPA
AGRGDRADAGLHAATVHRKPDVGRLGRKPPPQSQHRLRALSELGVVRIAGGSEVLLPRDVPRHVEQQGTQ
PDHALRRGISRPGTGVGQTPPGVAAADKYIAEREAKRLKGFDIPKHSRYTAGDGALTFQGTRTIEGQALA
LLKRGDEVMVMPIDQATARRLTRIAVGDAVSITAKGSIKTSKGRSR

Protein domains

Predicted by InterproScan

• Large polyvalent protein-associated domain 7 (LPD7) (422-508)

• Relaxase/Mobilisation nuclease domain (Relaxase) (12-251)

Protein structure

• AlphaFold DB: I2ALH0

Reference

[1] Leão SC et al. (2013) The detection and sequencing of a broad-host-range conjugative IncP-1尾 plasmid in an epidemic strain of Mycobacterium abscessus subsp. Bolletii. PLoS One. 8(4):e60746. [PMID:23565273]