Detailed information of relaxase

Relaxase

• ID: 26
• GenBank: CAD24395
• Name: TraI_pB4
• UniProt ID: Q8RSH1
• Family: MOB_P
• PDB ID: _
• Length: 752 a.a.
• Note: relaxase

Protein sequence

• Length: 752 a.a.
• Molecular weight: 83020.85 Da
• Isoelectric Point: 10.7945

>CAD24395.1 TraI protein (plasmid) [uncultured bacterium]
MIVKHVPMRSLGKSDFAGLVNYVTDAQSKDHRLGQVQITNCDAMSVQDAITEVLATQHTNTRAKGDKTYH
LIVSFRAGEQPSADTLRAIEERICAGLGFAEHQRVSAVHNDTDNLHIHIAINKIHPTRHTMHEPFGQHRT
LAELCVALERDYGLERDNHEPRQRGAEGRAADMERHAGVESLVGWIKRECLDEIKGAQSWQELHQVMHDN
GLELRERANGLVIEAGDGTMVKASTLARDLSKPKLEARLGPFEASPERQTRTKAKRQYQKDPIRLRVNTV
ELYARYKAEQQTLTATRGQALEQARRRKDRLVEAAKRSNRLRRATIKMVGENRTNKKLLYAQASKALRDE
IQAINKQYQQDRQALYDSHSRRTWADWLKKEATHGNAEALAALRAREAAQGLQGNTIQGRGDARPGHAPV
TDNITKKGTIIFRAGLSAVRDDGDKLQVSREATREGLQEALRLAMERYGSRITVNGTTQFKAQVIRAAVD
SQLPITFADPALESRRLALLKKENTHERPDRTERADQRPAEHRGRTGRGPGGPGQRAAAHDDAARPVAVA
RAGFGRPGAGRTDAAGVHAGAVHWKPDIGRIGRVPPPQSQHRLRTLSQLGVVRIAGGSEVLLPRDVPRHL
EQQGTQPDHQLRRGISRPGTGVAAAPPGLAAADKYIAEREAKRSKGFDIPKHARYTAGDGALAFQGVRNI
EGQALALLKRGDEVMVMPIDQATARRLSRIAVGDAVTVTPKGSIKTSKGRSR

Protein domains

Predicted by InterproScan

• Relaxase/Mobilisation nuclease domain (Relaxase) (12-251)

• Large polyvalent protein-associated domain 7 (LPD7) (420-507)

Protein structure

• AlphaFold DB: Q8RSH1

Reference

[1] Tauch A et al. (2003) The 79,370-bp conjugative plasmid pB4 consists of an IncP-1beta backbone loaded with a chromate resistance transposon, the strA-strB streptomycin resistance gene pair, the oxacillinase gene bla(NPS-1), and a tripartite antibiotic efflux system of the resistance-nodulation-division family. Mol Genet Genomics. 268(5):570-84. [PMID:12589432]