Detailed information of relaxase

Relaxase

• ID: 175
• GenBank: NP_835376
• Name: MobA_pTC-F14
• UniProt ID: Q840R3
• Family: MOB_P
• PDB ID: _
• Length: 889 a.a.
• Note: relaxase

Protein sequence

• Length: 889 a.a.
• Molecular weight: 102296.78 Da
• Isoelectric Point: 9.8238

>NP_835376.1 relaxase/primase-like fusion protein (plasmid) [Acidithiobacillus caldus]
MIVKKVKSNRTKGKAASIRDLTNYIREPQNRNPNEKVLYANGRGFISDTHAAQREEMVALAAEAVRSRNP
VNHYILSWREGEQPSPEQVEEAVSIFLDELGLQEHQVIYALHKDTDNLHLHIAVNRVHPETLKCVEINKG
FDLESAHRAIARIEHAQGWQREQNGRYEVLENGELGREHLEPNKRRQPEQRKRDKENRTGEKSAERIAIE
IGAPIIKQAQSWEQLHRELAAQGMRYEQKGSGALLWVGEVAVKASSADREASLGKLQKRLGAYEPAQAPS
PVAQRKPEPLQPDRPEWEDFMAGRKMHYAEKNAAKLSMDQRQEQERKALQARQQEQRKVLLGGRWNGKGE
ALNALRGVLAAEQAAEKAALKERHQQERQQWRQQYRPYPDFEQWLRREHGAEQATRWRYREAEPQRIEGD
STEAPKPRDIRAYRAEIVGQEVRYTPKSGAGGGPGGVSFVDKGRIIEIHDWRNQDTTLAALQLSAQKWGK
FTVTGNDEYKALCVKLAVEHGFQITNPELQEVIRQERQRMRQERAQAMKSEQIKPFERYAEAVGAERYRV
TSIKMRPDGSKQTFILDKRDGITRGFTPEEIAQRTPEMQRLQRRGENLYYTPLSEGKHHILIDDMDREKL
DRLIRDGYQPAVVLESSPGNYQAVITIPKLGTPFDKDVGNRLSDALNREYGDPKLSGAIHPHRAPGYENR
KPKHRREDGSYPEVRLLKAERRECGKTLALSREIDAGYQRQAAEKALKTPVEQFSEPNSTQTTPVSEKTA
TEAYWRHYRDVRKRQRGMLDLSRVDAMIAVRMRVTGFDQSAIEGAIYQCAPSIREQQESRDWTDYARRTA
RYAYSAAGDRQAADLGKYRQQWEKLEGRERQQEQAKAREIERNGPSMSR

Protein domains

Predicted by InterproScan

• Relaxase/Mobilisation nuclease domain (Relaxase) (17-272)

• Large polyvalent protein-associated domain 7 (LPD7) (453-527)

• RepB DNA-primase from phage plasmid (RepB_primase) (548-808)

Protein structure

• AlphaFold DB: Q840R3

Reference

[1] Rawlings DE (2005) The evolution of pTF-FC2 and pTC-F14, two related plasmids of the IncQ-family. Plasmid. 53(2):137-47. [PMID:15737401]
[2] van Zyl LJ et al. (2003) Analysis of the mobilization region of the broad-host-range IncQ-like plasmid pTC-F14 and its ability to interact with a related plasmid, pTF-FC2. J Bacteriol. 185(20):6104-11. [PMID:14526022]