Detailed information of relaxase

Relaxase

• ID: 1080
• GenBank: CAE52362
• Name: RelSt3
• UniProt ID: Q70CA7
• Family: MOB_T
• PDB ID: _
• Length: 410 a.a.

Protein sequence

• Length: 410 a.a.
• Molecular weight: 48429.03 Da
• Isoelectric Point: 7.2206

>CAE52362.1 putative transfer protein [Streptococcus thermophilus]
MTKISPFQIKNFRKQTGLSQKAFAQAVNLPIRTYRSYESGERGLTIDKFRKLKEKLGYYQECHKNNLRAH
IDYLRLTFPSLRDLETFCENFLFCHLSEFTDQETRLMNYTHLWQRGNIWIFDFFDKSATNNYQTCLQLSG
QGCREMELLLEHKGISWQTFLQNILYAYQDVRVKRLDIALDELYKGYGHEEEHIQIPKLIDKLYAKEIVL
DTIRKWNITGGGSFTDNDNMEANHGLSLYFGSRQSQLYFNFYEKRYEIARMENISLEESLEIFGIWNRYE
LRFSDQKAQGVVEEYINGVDLGEIARGIVNKEIQVYDGVTRFGSYKPYEKWQRLFGGVEPLKLSTSPQPY
SIERTIRWLTYQVANSLALVSEADKIMQTEYMKMIQNSGEITDRGEAILRLLKTNKHYEH

Protein domains

Predicted by InterproScan

• Helix-turn-helix (HTH_3) (9-57)

• Replication initiation factor (Rep_trans) (172-384)

• Rolling Circle replication initiation protein N-terminal domain (Rol_Rep_N) (69-162)

Protein structure

• AlphaFold DB: Q70CA7

Reference

[1] Haifa Laroussi et al. (2022) Exploration of DNA processing features unravels novel properties of ICE conjugation in Gram-positive bacteria.. Nucleic acids research. 50(14):8127-8142. [PMID:35849337]