Detailed information of relaxase

Relaxase

• ID: 105
• GenBank: CAJ43356
• Name: TraI_QKH54
• UniProt ID: Q1H9W9
• Family: MOB_P
• PDB ID: _
• Length: 802 a.a.
• Note: TraI DNA relaxase

Protein sequence

• Length: 802 a.a.
• Molecular weight: 87521.06 Da
• Isoelectric Point: 10.7582

>CAJ43356.1 TraI DNA relaxase (plasmid) [uncultured bacterium]
MIAKRIPMNSAKKSSFAGLVKYITSSQGINERVGQVRVTNCQTEELSWAVHEVLHTQKINTRAEGDKTYH
LLISLAPGEQPSSEVLRDIEDRVCSAIGYQDHQRVSAVHNDTDCLHIHIAINKIHPERHTLHEPYRDFKT
LGDICARLELEHGLQQVNHARKKSVSEGRANDMEQHAGIESLITWVRRECLEQVQGAKNWTELHQVLHEN
GLELRERGNGLVITDQAGTMVKASTVARDLSKGKLEERLGAFENQQQQARASHNQGKPLPRKPGIGRVGR
RPPPASKNRLRGLSTLQAIQIDSGKRYEKSPVKHKSDTTELYARFRDEQNAVRHTKAKELAAARERRDRA
IEQAKNVAKLKRSSIKLMATPGLTKKLLYASTHKSLQEQITSLRAEHIKAIENINTLNKARQWADWLQAK
ALDGDQDALKALRARQGVKGLQGDAVAAKGQQHSAKAVPIEQDHITKEGTVIYRAGTSAIRDDGSKLQLS
RGANFDGIETALRMAAARYGEKITITGSDQFKELVAQTAAIRSLPIKFDDPALEQRRQSLQQAIEKERNN
VGRTDRGRAAGSGAGVDGLHAARGGRGIGAGGTTGAGRGTGVRGSTAGTQLSGRAGTAASGRITVRAPGG
TPKPGVARVGRKPPPESQNRLRALSKLGVVQLTQGSEVLLPRDVPGVVEHQGAKPDNGLRRDVSRSGGIA
AEGKTISSAQAARQYVAEREDKRAKGFDIPKHRLYNQADDGPATFEGLRQVEGQSMALLKRGDELLVLPV
NEATARRMKRMKLGDPVTANATGAIKSKGRSR

Protein domains

Predicted by InterproScan

• Relaxase/Mobilisation nuclease domain (Relaxase) (12-250)

• Large polyvalent protein-associated domain 7 (LPD7) (462-550)

Protein structure

• AlphaFold DB: Q1H9W9

Reference

[1] Pachulec E et al. (2010) Conjugative Plasmids of Neisseria gonorrhoeae. PLoS One. 5(4):e9962. [PMID:20376355]
[2] Haines AS et al. (2006) Plasmids from freshwater environments capable of IncQ retrotransfer are diverse and include pQKH54, a new IncP-1 subgroup archetype. Microbiology. 152(Pt 9):2689-701. [PMID:16946264]