Detailed information of oriT

oriT


The information of the oriT region


oriTDB ID   200302
Name   oriT_ICE_EfmISMMSVRE1_Tn916 in_silico
Organism   Enterococcus faecium strain ISMMS_VRE_1
Sequence Completeness      -
NCBI accession of oriT (coordinates [strand])   CP012430 (_)
oriT length   134 nt
IRs (inverted repeats)      66..71, 84..89  (AAATCC..GGATTT)
Location of nic site      76..77
Conserved sequence flanking the
  nic site  
 
 TTTGGTTACA
Note   Predicted by oriTfinder 2.0

  oriT sequence  


Download         Length: 134 nt

>oriT_ICE_EfmISMMSVRE1_Tn916
ACTTAACCCCTCGGTATCTAACAGGGGGGTACAAATCGACAGGAAACAGTCAAAAAAACATTAGAAAATCCTTTGGTTACAAGGGATTTACAAAATTTCAGCGTATGTCAAATGGGCTTTAAAAGTTGACATAC

Visualization of oriT structure

  oriT secondary structure

Predicted by RNAfold.

Download structure file


Relaxase


ID   14340 GenBank   AOM16752
Name   Rep_trans_AL014_10945_ICE_EfmISMMSVRE1_Tn916 insolico UniProt ID   _
Length   401 a.a. PDB ID   
Note   Predicted by oriTfinder 2.0

  Relaxase protein sequence


Download         Length: 401 a.a.        Molecular weight: 47398.10 Da        Isoelectric Point: 6.5091

>AOM16752.1 Cro/Cl family transcriptional regulator [Enterococcus faecium]
MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIETGKVKPSEDLQQSLWEALERFNPDAP
LEMLFDYVRIRFPTTDVQQVVENILQLKLSYFLHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGR
GCRQFESYLLAQQRSWYEFFMDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRS
GELVRKEEKECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAVRDLL
VYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKPEPYSFQRTLNWLSHQV
APTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVKEQDVITTKK

  Protein domains


Predicted by InterproScan.

(15-53)

(169-373)

(73-161)


  Protein structure



No available structure.




T4CP


ID   16832 GenBank   AOM16753
Name   tcpA_AL014_10950_ICE_EfmISMMSVRE1_Tn916 insolico UniProt ID   _
Length   461 a.a. PDB ID   _
Note   Predicted by oriTfinder 2.0

  T4CP protein sequence


Download         Length: 461 a.a.        Molecular weight: 53370.27 Da        Isoelectric Point: 9.0687

>AOM16753.1 cell division protein FtsK [Enterococcus faecium]
MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQINWQDFNLSQADKIDIPYLIISFSVAIL
ICLLVAFVFKRVRYDTVKQLYHRQKLAKMILENKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKN
GLIQIRVEITLGKYQDQLLHLEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRL
MKNVWWEYDKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRKEDLL
SCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTKENTAVMNKLKQIVMLG
RQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYGMMFGSDVQKDFFLKRIKGRGYVDVGTSV
ISEFYTPLVPKGYDFLEEIKKLSNSRQSTQATCEAEVAGVD

  Protein domains


Predicted by InterproScan.

(217-301)

  Protein structure



No available structure.




T4SS


T4SS were predicted by using oriTfinder2.

Region 1: 2173395..2601155

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL014_10895 2169628..2171001 - 1374 AOM16742 tetracycline resistance protein -
AL014_10900 2171099..2173018 - 1920 AOM16743 tetracycline resistance protein tetM -
AL014_10905 2173395..2174309 - 915 AOM16744 conjugal transfer protein orf13
AL014_10910 2174324..2175325 - 1002 AOM16745 peptidase P60 orf14
AL014_10915 2175322..2177505 - 2184 AOM16746 hypothetical protein orf15
AL014_10920 2177508..2179955 - 2448 AOM16747 ATP/GTP-binding protein virb4
AL014_10925 2179939..2180331 - 393 AOM16748 hypothetical protein orf17a
AL014_10930 2180418..2180915 - 498 AOM16749 antirestriction protein ArdA -
AL014_10935 2181032..2181283 - 252 AOM16750 conjugal transfer protein orf19
AL014_10940 2181359..2183269 - 1911 AOM16751 reverse transcriptase -
AL014_10945 2184053..2185258 - 1206 AOM16752 Cro/Cl family transcriptional regulator -
AL014_10950 2185437..2186822 - 1386 AOM16753 cell division protein FtsK virb4
AL014_10955 2186851..2187237 - 387 AOM16754 conjugal transfer protein orf23
AL014_10960 2187253..2187567 - 315 AOM16755 conjugal transfer protein orf23
AL014_10965 2187920..2188399 - 480 AOM16756 50S rRNA methyltransferase -
AL014_10970 2188827..2190116 + 1290 AOM16757 serine protease -
AL014_10975 2190155..2190760 - 606 AOM16758 tRNA-binding protein -
AL014_10980 2190956..2191420 - 465 AOM16759 universal stress protein UspA -
AL014_10985 2191442..2191762 - 321 AOM16760 thioredoxin -
AL014_10990 2191905..2192984 - 1080 AOM16761 glutamyl aminopeptidase -
AL014_10995 2193184..2193534 + 351 AOM16762 peptidase -
AL014_11000 2193719..2194672 + 954 AOM16763 glycosyl transferase -
AL014_11005 2194685..2196472 + 1788 AOM16764 hypothetical protein -
AL014_11010 2196459..2197661 + 1203 AOM16765 hypothetical protein -
AL014_11015 2197866..2199161 + 1296 AOM16766 transposase -
AL014_11020 2199259..2200677 - 1419 AOM16767 dipeptidase PepV -
AL014_11025 2200826..2201671 + 846 AOM16768 carbohydrate kinase -
AL014_11030 2201675..2202115 + 441 AOM16769 acyl-CoA thioester hydrolase -
AL014_11035 2202192..2202359 + 168 AOM17632 hypothetical protein -
AL014_11040 2202495..2203181 + 687 AOM16770 GntR family transcriptional regulator -
AL014_11045 2203589..2204278 - 690 AOM16771 hypothetical protein -
AL014_11050 2204253..2206382 - 2130 AOM16772 hydantoinase -
AL014_11060 2207423..2208610 + 1188 AOM16773 transposase -
AL014_11070 2209494..2209853 - 360 AOM16774 50S ribosomal protein L20 -
AL014_11075 2209906..2210106 - 201 AOM16775 50S ribosomal protein L35 -
AL014_11080 2210178..2210702 - 525 AOM16776 translation initiation factor IF-3 -
AL014_11085 2211022..2211654 + 633 AOM16777 hypothetical protein -
AL014_11090 2211656..2212561 - 906 AOM16778 magnesium transporter CorA -
AL014_11095 2212646..2213305 - 660 AOM16779 deoxyadenosine kinase -
AL014_11100 2213621..2214565 + 945 AOM16780 mevalonate kinase -
AL014_11105 2214558..2215535 + 978 AOM16781 diphosphomevalonate decarboxylase -
AL014_11110 2215548..2216633 + 1086 AOM16782 phosphomevalonate kinase -
AL014_11115 2216630..2217694 + 1065 AOM16783 isopentenyl pyrophosphate isomerase -
AL014_11120 2217943..2218746 - 804 AOM16784 gluconate 5-dehydrogenase -
AL014_11130 2219053..2219277 - 225 AOM16785 hypothetical protein -
AL014_11135 2219303..2220109 - 807 AOM16786 integrase -
AL014_11140 2220106..2220642 - 537 AOM16787 transposase -
AL014_11150 2221268..2221747 - 480 AOM16788 C4-dicarboxylate ABC transporter -
AL014_11155 2221753..2222610 - 858 AOM16789 hypothetical protein -
AL014_11160 2222794..2223900 - 1107 AOM16790 glycosyl hydrolase family 88 -
AL014_11165 2224129..2226726 - 2598 AOM16791 acetaldehyde dehydrogenase -
AL014_11170 2227031..2227411 - 381 AOM16792 preprotein translocase subunit YajC -
AL014_11175 2227508..2228653 - 1146 AOM16793 queuine tRNA-ribosyltransferase -
AL014_11180 2228871..2229569 + 699 AOM16794 hypothetical protein -
AL014_11185 2229737..2232376 - 2640 AOM16795 metal ABC transporter ATPase -
AL014_11190 2233018..2234313 - 1296 AOM16796 transposase -
AL014_11195 2234517..2235548 - 1032 AOM16797 S-adenosylmethionine tRNA ribosyltransferase -
AL014_11205 2236499..2237647 - 1149 AOM16798 transposase -
AL014_11210 2237664..2238068 - 405 AOM16799 transposase -
AL014_11220 2238811..2239452 + 642 AOM16800 choline ABC transporter permease -
AL014_11225 2239449..2240366 + 918 AOM16801 glycine/betaine ABC transporter substrate-binding protein -
AL014_11230 2240363..2241034 + 672 AOM16802 amino acid ABC transporter permease -
AL014_11235 2241575..2242063 - 489 AOM16803 mannosyl-glycoprotein endo-beta-N-acetylglucosamidase -
AL014_11240 2242264..2242530 - 267 AOM16804 addiction module protein -
AL014_11245 2242530..2242793 - 264 AOM16805 prevent-host-death protein -
AL014_11250 2243269..2243454 + 186 AOM17633 transcriptional regulator -
AL014_11255 2243596..2245419 - 1824 AOM16806 amino acid permease -
AL014_11260 2246017..2248722 - 2706 AOM16807 phage infection protein -
AL014_11265 2249028..2249975 - 948 AOM16808 alcohol dehydrogenase -
AL014_11270 2250165..2250434 + 270 AOM16809 30S ribosomal protein S14 -
AL014_11275 2250610..2250972 - 363 AOM16810 PemK family transcriptional regulator -
AL014_11280 2250983..2252104 - 1122 AOM16811 alanine racemase -
AL014_11285 2252120..2252470 - 351 AOM16812 4'-phosphopantetheinyl transferase -
AL014_11290 2252600..2254111 - 1512 AOM16813 DEAD/DEAH box helicase -
AL014_11295 2254433..2255785 - 1353 AOM17634 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase -
AL014_11300 2255938..2257014 - 1077 AOM16814 D-alanine--D-alanine ligase -
AL014_11305 2257210..2258955 + 1746 AOM16815 ABC transporter -
AL014_11310 2259235..2259672 - 438 AOM16816 hypothetical protein -
AL014_11315 2259656..2261029 - 1374 AOM16817 hypothetical protein -
AL014_11320 2261351..2261839 - 489 AOM16818 GCN5 family acetyltransferase -
AL014_11325 2261861..2262463 - 603 AOM16819 hypothetical protein -
AL014_11330 2262562..2263098 + 537 AOM16820 transposase -
AL014_11335 2263095..2263901 + 807 AOM16821 integrase -
AL014_11340 2264386..2265015 - 630 AOM16822 uridine kinase -
AL014_11345 2265099..2265794 - 696 AOM16823 HAD family hydrolase -
AL014_11350 2265807..2266523 - 717 AOM16824 pseudouridylate synthase -
AL014_11355 2266853..2267458 + 606 AOM16825 50S ribosomal protein L25 -
AL014_11360 2267783..2268106 + 324 AOM16826 GTP cyclohydrolase -
AL014_11365 2268288..2269658 + 1371 AOM16827 diguanylate cyclase -
AL014_11370 2269788..2271089 - 1302 AOM16828 hemolysin -
AL014_11375 2271319..2273310 - 1992 AOM16829 potassium transporter Kup -
AL014_11380 2273454..2273720 - 267 AOM16830 hypothetical protein -
AL014_11385 2274230..2276356 - 2127 AOM17635 polynucleotide phosphorylase -
AL014_11390 2276544..2276813 - 270 AOM16831 30S ribosomal protein S15 -
AL014_11395 2277064..2277627 + 564 AOM16832 peptide deformylase -
AL014_11400 2277880..2278401 - 522 AOM16833 DNA-binding protein -
AL014_11405 2278404..2279246 - 843 AOM16834 maltose acetyltransferase -
AL014_11410 2279239..2279964 - 726 AOM16835 transcriptional regulator -
AL014_11415 2280140..2280436 + 297 AOM16836 hypothetical protein -
AL014_11420 2280605..2280961 - 357 AOM16837 hypothetical protein -
AL014_11425 2281004..2282596 + 1593 AOM16838 amino acid ABC transporter permease -
AL014_11430 2282609..2283349 + 741 AOM16839 ABC transporter -
AL014_11435 2283517..2284866 + 1350 AOM16840 D-alanine/D-serine/glycine permease -
AL014_11440 2284994..2285584 - 591 AOM16841 hypothetical protein -
AL014_11445 2285731..2287083 + 1353 AOM16842 branched-chain amino acid transporter II carrier protein -
AL014_11450 2287557..2288735 - 1179 AOM16843 transposase -
AL014_11455 2289165..2289539 - 375 AOM16844 hypothetical protein -
AL014_11460 2289656..2290138 - 483 AOM16845 protein tyrosine phosphatase -
AL014_11465 2290190..2290768 - 579 AOM16846 TetR family transcriptional regulator -
AL014_11470 2290797..2291798 - 1002 AOM16847 ATP-dependent DNA helicase RuvB -
AL014_11475 2291811..2292413 - 603 AOM16848 ATP-dependent DNA helicase RuvA -
AL014_11480 2292583..2293029 - 447 AOM16849 methionine sulfoxide reductase B -
AL014_11485 2293106..2293819 - 714 AOM16850 GntR family transcriptional regulator -
AL014_11490 2294042..2296030 + 1989 AOM16851 PTS maltose transporter subunit IIBC -
AL014_11495 2296115..2296675 - 561 AOM16852 septum formation protein Maf -
AL014_11500 2296697..2298805 - 2109 AOM16853 DNA mismatch repair protein MutL -
AL014_11505 2298823..2301468 - 2646 AOM16854 DNA mismatch repair protein MutS -
AL014_11510 2301452..2301826 - 375 AOM16855 hypothetical protein -
AL014_11515 2301843..2302640 - 798 AOM16856 metallophosphoesterase -
AL014_11520 2303048..2303821 - 774 AOM16857 HAD family hydrolase -
AL014_11525 2303841..2304476 - 636 AOM16858 6-O-methylguanine DNA methyltransferase -
AL014_11530 2304504..2305301 - 798 AOM16859 formate-nitrite transporter -
AL014_11535 2305617..2306228 + 612 AOM16860 30S ribosomal protein S4 -
AL014_11540 2306368..2306907 + 540 AOM16861 biotin synthase -
AL014_11545 2306982..2307491 - 510 AOM16862 hypothetical protein -
AL014_11550 2307871..2308632 - 762 AOM16863 3-ketoacyl-ACP reductase -
AL014_11555 2308629..2308850 - 222 AOM16864 hypothetical protein -
AL014_11560 2308869..2310389 - 1521 AOM16865 M protein trans-acting positive regulator -
AL014_11565 2310455..2311156 - 702 AOM16866 hypothetical protein -
AL014_11570 2311149..2311559 - 411 AOM16867 murein hydrolase transporter LrgA -
AL014_11575 2311886..2312620 + 735 AOM16868 glycerol uptake permease -
AL014_11580 2312773..2313726 + 954 AOM16869 integrase -
AL014_11585 2313780..2314736 - 957 AOM16870 hypothetical protein -
AL014_11590 2314861..2316039 - 1179 AOM16871 transposase -
AL014_11595 2316137..2316595 - 459 AOM16872 M protein trans-acting positive regulator -
AL014_11600 2316902..2317999 - 1098 AOM16873 cell surface protein -
AL014_11605 2318107..2320134 - 2028 AOM16874 lectin -
AL014_11610 2320279..2321007 - 729 AOM17636 cell surface protein -
AL014_11615 2321527..2322426 - 900 AOM16875 metallophosphoesterase -
AL014_11620 2322436..2322792 - 357 AOM16876 hypothetical protein -
AL014_11625 2323147..2323443 + 297 AOM16877 hypothetical protein -
AL014_11630 2324087..2325040 - 954 AOM16878 iron ABC transporter substrate-binding protein -
AL014_11635 2325063..2325818 - 756 AOM16879 iron ABC transporter ATP-binding protein -
AL014_11640 2325815..2326774 - 960 AOM16880 iron ABC transporter permease -
AL014_11645 2326767..2327717 - 951 AOM16881 iron ABC transporter permease -
AL014_11650 2327867..2328319 + 453 AOM16882 hypothetical protein -
AL014_11655 2328408..2330672 - 2265 AOM17637 bifunctional glutamate--cysteine ligase/glutathione synthetase -
AL014_11660 2330862..2331860 - 999 AOM16883 cell division protein FtsY -
AL014_11665 2331871..2332680 - 810 AOM16884 haloacid dehalogenase -
AL014_11670 2332689..2336270 - 3582 AOM16885 chromosome segregation protein SMC -
AL014_11675 2336290..2336976 - 687 AOM16886 ribonuclease III -
AL014_11680 2337324..2339105 - 1782 AOM16887 peptide ABC transporter substrate-binding protein -
AL014_11685 2339131..2340045 - 915 AOM16888 peptide ABC transporter permease -
AL014_11690 2340072..2341034 - 963 AOM16889 peptide ABC transporter permease -
AL014_11695 2341034..2341978 - 945 AOM16890 peptide ABC transporter substrate-binding protein -
AL014_11700 2341979..2342983 - 1005 AOM16891 peptide ABC transporter ATPase -
AL014_11705 2343364..2344659 + 1296 AOM16892 transposase -
AL014_11710 2344773..2345015 - 243 AOM16893 acyl carrier protein -
AL014_11715 2345137..2346138 - 1002 AOM16894 phosphate acyltransferase -
AL014_11720 2346187..2348223 - 2037 AOM16895 ATP-dependent DNA helicase -
AL014_11725 2348340..2350022 - 1683 AOM16896 hypothetical protein -
AL014_11730 2350074..2350436 - 363 AOM16897 hypothetical protein -
AL014_11735 2350706..2350894 + 189 AOM16898 50S ribosomal protein L28 -
AL014_11740 2351132..2353801 + 2670 AOM16899 copper ABC transporter permease -
AL014_11745 2354134..2354880 - 747 AOM16900 pseudouridine synthase -
AL014_11750 2355083..2355880 - 798 AOM16901 cobalt ABC transporter ATP-binding protein -
AL014_11755 2355870..2356739 - 870 AOM16902 cobalt ABC transporter -
AL014_11760 2356715..2357554 - 840 AOM16903 cobalt transporter ATP-binding subunit -
AL014_11765 2357826..2358206 - 381 AOM16904 50S ribosomal protein L17 -
AL014_11770 2358234..2359172 - 939 AOM16905 DNA-directed RNA polymerase subunit alpha -
AL014_11775 2359252..2359641 - 390 AOM16906 30S ribosomal protein S11 -
AL014_11780 2359669..2360034 - 366 AOM16907 30S ribosomal protein S13 -
AL014_11785 2360052..2360168 - 117 AOM16908 50S ribosomal protein L36 -
AL014_11790 2360201..2360419 - 219 AOM16909 translation initiation factor IF-1 -
AL014_11795 2360610..2361257 - 648 AOM16910 adenylate kinase -
AL014_11800 2361319..2362614 - 1296 AOM16911 preprotein translocase subunit SecY -
AL014_11805 2362614..2363054 - 441 AOM16912 50S ribosomal protein L15 -
AL014_11810 2363098..2363277 - 180 AOM16913 50S ribosomal protein L30 -
AL014_11815 2363292..2363792 - 501 AOM16914 30S ribosomal protein S5 -
AL014_11820 2363813..2364169 - 357 AOM16915 50S ribosomal protein L18 -
AL014_11825 2364330..2364866 - 537 AOM16916 50S ribosomal protein L6 -
AL014_11830 2364898..2365296 - 399 AOM16917 30S ribosomal protein S8 -
AL014_11835 2365332..2365517 - 186 AOM16918 30S ribosomal protein S14 -
AL014_11840 2365536..2366075 - 540 AOM16919 50S ribosomal protein L5 -
AL014_11845 2366103..2366411 - 309 AOM16920 50S ribosomal protein L24 -
AL014_11850 2366448..2366816 - 369 AOM16921 50S ribosomal protein L14 -
AL014_11855 2366874..2367140 - 267 AOM16922 30S ribosomal protein S17 -
AL014_11860 2367165..2367353 - 189 AOM16923 50S ribosomal protein L29 -
AL014_11865 2367343..2367777 - 435 AOM16924 50S ribosomal protein L16 -
AL014_11870 2367780..2368436 - 657 AOM16925 30S ribosomal protein S3 -
AL014_11875 2368450..2368797 - 348 AOM16926 50S ribosomal protein L22 -
AL014_11880 2368820..2369098 - 279 AOM16927 30S ribosomal protein S19 -
AL014_11885 2369141..2369974 - 834 AOM16928 50S ribosomal protein L2 -
AL014_11890 2370013..2370303 - 291 AOM16929 50S ribosomal protein L23 -
AL014_11895 2370303..2370926 - 624 AOM16930 50S ribosomal protein L4 -
AL014_11900 2370954..2371583 - 630 AOM16931 50S ribosomal protein L3 -
AL014_11905 2371614..2371922 - 309 AOM16932 30S ribosomal protein S10 -
AL014_11910 2372329..2373516 - 1188 AOM16933 elongation factor Tu -
AL014_11915 2373688..2375775 - 2088 AOM16934 elongation factor G -
AL014_11920 2375869..2376339 - 471 AOM16935 30S ribosomal protein S7 -
AL014_11925 2376423..2376836 - 414 AOM16936 30S ribosomal protein S12 -
AL014_11930 2377155..2377838 + 684 AOM16937 ribose 5-phosphate isomerase -
AL014_11935 2377971..2378552 + 582 AOM16938 resolvase -
AL014_11940 2378724..2379410 + 687 AOM16939 phosphoglyceromutase -
AL014_11945 2379708..2380415 - 708 AOM16940 purine nucleoside phosphorylase -
AL014_11950 2380432..2381250 - 819 AOM16941 purine nucleoside phosphorylase -
AL014_11955 2381274..2382440 - 1167 AOM16942 phosphopentomutase -
AL014_11960 2382539..2383495 - 957 AOM16943 sugar ABC transporter permease -
AL014_11965 2383495..2384628 - 1134 AOM16944 branched-chain amino acid ABC transporter permease -
AL014_11970 2384621..2386183 - 1563 AOM16945 heme ABC transporter ATP-binding protein -
AL014_11975 2386395..2387477 - 1083 AOM16946 hypothetical protein -
AL014_11980 2387543..2387941 - 399 AOM16947 cytidine deaminase -
AL014_11985 2387962..2388624 - 663 AOM16948 deoxyribose-phosphate aldolase -
AL014_11990 2388670..2389971 - 1302 AOM16949 thymidine phosphorylase -
AL014_11995 2390112..2391128 - 1017 AOM16950 LacI family transcriptional regulator -
AL014_12000 2391436..2392041 - 606 AOM16951 methyltransferase -
AL014_12005 2392237..2393160 + 924 AOM16952 pantothenate kinase -
AL014_12010 2393219..2394784 + 1566 AOM16953 GMP synthase -
AL014_12015 2394852..2396045 - 1194 AOM16954 integrase -
AL014_12020 2396072..2396272 - 201 AOM16955 conjugal transfer protein -
AL014_12025 2396770..2397000 - 231 AOM16956 hypothetical protein -
AL014_12030 2396997..2397419 - 423 AOM16957 DNA-binding protein -
AL014_12035 2397950..2398303 + 354 AOM16958 DNA-binding protein -
AL014_12045 2400049..2400546 + 498 AOM16959 dihydrofolate reductase -
AL014_12050 2400618..2402570 - 1953 AOM16960 insertion element protein -
AL014_12055 2402577..2402873 - 297 AOM16961 hypothetical protein -
AL014_12065 2404045..2405340 + 1296 AOM16962 transposase -
AL014_12070 2405750..2406679 - 930 AOM16963 conjugal transfer protein -
AL014_12075 2406696..2407718 - 1023 AOM16964 peptidase P60 -
AL014_12080 2407715..2409742 - 2028 AOM16965 hypothetical protein -
AL014_12085 2409739..2412192 - 2454 AOM16966 ATP/GTP-binding protein -
AL014_12090 2412176..2412571 - 396 AOM16967 hypothetical protein -
AL014_12095 2412643..2413281 - 639 AOM16968 hypothetical protein -
AL014_12100 2413337..2413837 - 501 AOM16969 antirestriction protein ArdA -
AL014_12105 2413898..2414677 - 780 AOM16970 hypothetical protein -
AL014_12110 2414719..2414940 - 222 AOM16971 conjugal transfer protein -
AL014_12115 2414937..2415227 - 291 AOM16972 hypothetical protein -
AL014_12120 2415224..2416408 - 1185 AOM16973 Cro/Cl family transcriptional regulator -
AL014_12125 2416590..2418011 - 1422 AOM16974 cell division protein FtsK -
AL014_12130 2418015..2418788 - 774 AOM17638 hypothetical protein -
AL014_12135 2418798..2419175 - 378 AOM16975 conjugal transfer protein -
AL014_12140 2419196..2419510 - 315 AOM16976 conjugal transfer protein -
AL014_12145 2419710..2421503 - 1794 AOM16977 AAA family ATPase -
AL014_12150 2421500..2423689 - 2190 AOM16978 ATP-dependent endonuclease -
AL014_12155 2423823..2425013 - 1191 AOM16979 transposase -
AL014_12160 2425885..2427516 - 1632 AOM16980 beta-1,4-galactanase -
AL014_12165 2427530..2429203 - 1674 AOM16981 PTS lactose transporter subunit IIBC -
AL014_12170 2429216..2429533 - 318 AOM16982 PTS lactose transporter subunit IIA -
AL014_12175 2429558..2430958 - 1401 AOM16983 6-phospho-beta-galactosidase -
AL014_12180 2431195..2431980 + 786 AOM16984 DeoR faimly transcriptional regulator -
AL014_12185 2431983..2432675 + 693 AOM16985 pesticidal protein Cry10Aa -
AL014_12190 2432949..2433320 - 372 AOM16986 Cro/Cl family transcriptional regulator -
AL014_12195 2433720..2433950 - 231 AOM16987 hypothetical protein -
AL014_12200 2434044..2434382 - 339 AOM17639 hypothetical protein -
AL014_12205 2435902..2436780 - 879 AOM16988 hypothetical protein -
AL014_12210 2437127..2438152 - 1026 AOM16989 hypothetical protein -
AL014_12215 2438511..2439014 + 504 AOM16990 protein vanZ -
AL014_12220 2439827..2439964 - 138 AOM16991 hypothetical protein -
AL014_12225 2440059..2440637 - 579 AOM16992 hypothetical protein -
AL014_12230 2440806..2441003 + 198 AOM16993 hypothetical protein -
AL014_12235 2441106..2441924 - 819 AOM16994 dihydroorotate dehydrogenase -
AL014_12240 2442089..2443819 + 1731 AOM16995 pyruvate oxidase -
AL014_12245 2444005..2444526 - 522 AOM17640 hypothetical protein -
AL014_12250 2444775..2446397 + 1623 AOM16996 ABC transporter ATP-binding protein -
AL014_12255 2446526..2447389 - 864 AOM16997 fatty acid-binding protein DegV -
AL014_12260 2448138..2449433 + 1296 AOM16998 transposase -
AL014_12265 2449636..2450928 - 1293 AOM16999 adenylosuccinate synthetase -
AL014_12270 2451708..2453075 - 1368 AOM17000 DNA helicase -
AL014_12275 2453349..2453801 - 453 AOM17001 50S ribosomal protein L9 -
AL014_12280 2453807..2455780 - 1974 AOM17002 phosphoesterase -
AL014_12285 2455923..2456159 - 237 AOM17003 30S ribosomal protein S18 -
AL014_12290 2456185..2456697 - 513 AOM17004 single-stranded DNA-binding protein -
AL014_12295 2456747..2457046 - 300 AOM17005 30S ribosomal protein S6 -
AL014_12300 2457282..2459753 - 2472 AOM17006 DNA gyrase subunit A -
AL014_12305 2459773..2461719 - 1947 AOM17007 DNA gyrase subunit B -
AL014_12310 2461716..2462840 - 1125 AOM17008 recombinase RecF -
AL014_12315 2462827..2463069 - 243 AOM17009 RNA-binding protein -
AL014_12320 2463298..2464428 - 1131 AOM17010 DNA polymerase III subunit beta -
AL014_12325 2464626..2465960 - 1335 AOM17011 chromosomal replication initiator protein DnaA -
AL014_12330 2466483..2466617 + 135 AOM17012 50S ribosomal protein L34 -
AL014_12335 2466735..2467091 + 357 AOM17013 ribonuclease P -
AL014_12340 2467088..2467906 + 819 AOM17014 hypothetical protein -
AL014_12345 2467924..2468682 + 759 AOM17015 RNA-binding protein -
AL014_12350 2468850..2469188 - 339 AOM17016 hypothetical protein -
AL014_12355 2469532..2470929 + 1398 AOM17017 tRNA modification GTPase -
AL014_12360 2470946..2472847 + 1902 AOM17018 tRNA uridine 5-carboxymethylaminomethyl modification protein -
AL014_12365 2473079..2473792 + 714 AOM17641 16S rRNA methyltransferase -
AL014_12370 2473804..2474571 + 768 AOM17019 sporulation initiation inhibitor Soj -
AL014_12375 2474558..2475448 + 891 AOM17020 chromosome partitioning protein ParB -
AL014_12380 2475469..2475660 + 192 AOM17021 hypothetical protein -
AL014_12385 2475669..2476769 + 1101 AOM17022 GTP-binding protein -
AL014_12390 2476859..2477554 + 696 AOM17023 hypothetical protein -
AL014_12395 2478059..2479543 + 1485 AOM17024 inosine-5-monophosphate dehydrogenase -
AL014_12400 2480092..2481363 - 1272 AOM17025 serine--tRNA ligase -
AL014_12405 2481657..2482865 - 1209 AOM17026 histidine kinase -
AL014_12410 2482852..2483541 - 690 AOM17027 PhoB family transcriptional regulator -
AL014_12415 2483962..2484171 - 210 AOM17028 hypothetical protein -
AL014_12480 2490282..2490749 + 468 AOM17029 CtsR family transcriptional regulator -
AL014_12485 2490756..2493248 + 2493 AOM17030 Clp protease ClpX -
AL014_12490 2493469..2494392 + 924 AOM17031 peptidase U32 -
AL014_12495 2494410..2495651 + 1242 AOM17642 protease -
AL014_12500 2495785..2497131 + 1347 AOM17032 glutathione reductase -
AL014_12505 2498066..2499019 - 954 AOM17033 1,4-dihydroxy-2-naphthoate prenyltransferase -
AL014_12510 2499032..2500135 - 1104 AOM17034 thiamine biosynthesis protein ApbE -
AL014_12515 2500225..2501160 - 936 AOM17035 FMN-binding protein -
AL014_12520 2501462..2503396 + 1935 AOM17036 NADH dehydrogenase -
AL014_12525 2503853..2504269 + 417 AOM17037 hypothetical protein -
AL014_12530 2504283..2504849 + 567 AOM17038 heptaprenyl diphosphate synthase -
AL014_12535 2504872..2505858 + 987 AOM17039 geranylgeranyl pyrophosphate synthase -
AL014_12540 2506013..2507995 - 1983 AOM17040 cell surface protein -
AL014_12545 2508282..2508806 + 525 AOM17041 hypothetical protein -
AL014_12550 2509123..2510091 - 969 AOM17042 biotin--acetyl-CoA-carboxylase ligase -
AL014_12555 2510248..2511054 - 807 AOM17043 ABC transporter ATP-binding protein -
AL014_12560 2511051..2511956 - 906 AOM17044 ABC transporter permease -
AL014_12565 2511974..2512942 - 969 AOM17045 ABC transporter substrate-binding protein -
AL014_12570 2513661..2517287 + 3627 AOM17046 DNA-directed RNA polymerase subunit beta -
AL014_12575 2517366..2521019 + 3654 AOM17047 DNA-directed RNA polymerase subunit beta' -
AL014_12580 2521614..2522639 - 1026 AOM17048 LacI family transcriptional regulator -
AL014_12585 2522914..2524599 + 1686 AOM17049 sugar phosphorylase -
AL014_12590 2524613..2525896 + 1284 AOM17050 sugar ABC transporter substrate-binding protein -
AL014_12595 2525966..2526835 + 870 AOM17051 sugar ABC transporter permease -
AL014_12600 2526832..2527668 + 837 AOM17052 sugar ABC transporter permease -
AL014_12605 2527694..2528761 + 1068 AOM17053 alcohol dehydrogenase -
AL014_12610 2528758..2529585 + 828 AOM17054 hypothetical protein -
AL014_12615 2529630..2530655 + 1026 AOM17055 oxidoreductase -
AL014_12620 2530652..2532835 + 2184 AOM17056 glycosyl hydrolase family 65 -
AL014_12625 2532835..2533965 + 1131 AOM17057 glycerate kinase -
AL014_12630 2533962..2534639 + 678 AOM17058 beta-phosphoglucomutase -
AL014_12635 2534723..2535250 + 528 AOM17059 methionine sulfoxide reductase A -
AL014_12640 2535451..2536137 - 687 AOM17060 peptidase A24 -
AL014_12645 2536217..2537755 + 1539 AOM17061 gluconate kinase -
AL014_12650 2537875..2538342 + 468 AOM17062 ferritin -
AL014_12655 2538861..2539304 + 444 AOM17063 50S ribosomal protein L13 -
AL014_12660 2539320..2539712 + 393 AOM17064 30S ribosomal protein S9 -
AL014_12665 2539805..2541025 - 1221 AOM17065 integrase -
AL014_12670 2541943..2542683 + 741 AOM17066 manganese ABC transporter ATP-binding protein -
AL014_12675 2542775..2543962 - 1188 AOM17067 transposase -
AL014_12680 2544284..2545126 + 843 AOM17068 manganese ABC transporter substrate-binding protein -
AL014_12685 2545123..2546073 + 951 AOM17069 manganese ABC transporter substrate-binding protein -
AL014_12690 2546088..2546321 + 234 AOM17070 iron-dependent repressor -
AL014_12695 2546718..2547236 + 519 AOM17071 TetR family transcriptional regulator -
AL014_12700 2547367..2548035 + 669 AOM17072 cobalt transporter -
AL014_12705 2548046..2549461 + 1416 AOM17073 ABC transporter ATP-binding protein -
AL014_12710 2549479..2550048 + 570 AOM17074 hypothetical protein -
AL014_12715 2550158..2551912 + 1755 AOM17075 ABC transporter ATP-binding protein -
AL014_12720 2551866..2553638 + 1773 AOM17076 ABC transporter ATP-binding protein -
AL014_12725 2554161..2554430 + 270 AOM17077 30S ribosomal protein S14 -
AL014_12730 2554445..2554624 + 180 AOM17078 50S ribosomal protein L32 -
AL014_12735 2554656..2555033 + 378 AOM17079 hypothetical protein -
AL014_12740 2555054..2555203 + 150 AOM17080 50S ribosomal protein L33 -
AL014_12745 2555227..2556210 + 984 AOM17081 cobalamin biosynthesis protein CobW -
AL014_12750 2556240..2556362 + 123 AOM17082 hypothetical protein -
AL014_12755 2556380..2557903 + 1524 AOM17083 zinc-binding protein -
AL014_12760 2557927..2558166 + 240 AOM17084 hypothetical protein -
AL014_12765 2558359..2558820 - 462 AOM17085 transposase -
AL014_12770 2559015..2559233 - 219 AOM17086 transposase -
AL014_12775 2559351..2560967 + 1617 AOM17087 cobalamin biosynthesis protein -
AL014_12780 2561208..2562335 - 1128 AOM17643 transposase -
AL014_12790 2563275..2563607 - 333 AOM17088 transposase -
AL014_12795 2564121..2564312 - 192 AOM17089 hypothetical protein -
AL014_12800 2564406..2564792 - 387 AOM17090 hypothetical protein -
AL014_12805 2565486..2566691 + 1206 AOM17091 AraC family transcriptional regulator -
AL014_12810 2566708..2567142 + 435 AOM17092 hypothetical protein -
AL014_12815 2567587..2568792 + 1206 AOM17644 transposase -
AL014_12820 2568728..2568970 + 243 AOM17093 hypothetical protein -
AL014_12835 2575860..2576576 + 717 AOM17645 transporter -
AL014_12840 2576710..2578053 + 1344 AOM17094 pyridine nucleotide-disulfide oxidoreductase -
AL014_12845 2578165..2579616 + 1452 AOM17095 N-acetylmuramoyl-L-alanine amidase cd419a
AL014_12850 2579965..2580597 + 633 AOM17096 hypothetical protein -
AL014_12855 2581185..2582624 + 1440 AOM17097 multidrug MFS transporter -
AL014_12860 2583386..2583601 + 216 AOM17098 hypothetical protein -
AL014_12865 2583913..2584074 - 162 AOM17099 transposase -
AL014_12870 2584261..2585172 - 912 AOM17100 conjugal transfer protein orf13
AL014_12875 2585191..2586195 - 1005 AOM17101 peptidase P60 orf14
AL014_12880 2586192..2588315 - 2124 AOM17102 conjugal transfer protein orf15
AL014_12885 2588320..2590767 - 2448 AOM17103 ATP/GTP-binding protein virb4
AL014_12890 2590754..2591143 - 390 AOM17104 hypothetical protein orf17a
AL014_12895 2591203..2591706 - 504 AOM17105 antirestriction protein ArdA -
AL014_12900 2591719..2591943 - 225 AOM17106 conjugal transfer protein orf19
AL014_12905 2592047..2593957 - 1911 AOM17107 reverse transcriptase -
AL014_12910 2594703..2594822 - 120 AOM17108 hypothetical protein -
AL014_12915 2594837..2596021 - 1185 AOM17109 Cro/Cl family transcriptional regulator -
AL014_12920 2596280..2596570 - 291 AOM17110 hypothetical protein -
AL014_12925 2596560..2597267 - 708 AOM17111 DNA methylase -
AL014_12930 2597268..2597702 - 435 AOM17112 DNA methyltransferase -
AL014_12935 2597935..2598501 - 567 AOM17113 zeta toxin family protein -
AL014_12940 2598686..2600026 - 1341 AOM17114 cell division protein FtsK virb4
AL014_12945 2600109..2600444 - 336 AOM17115 damage-inducible protein J -
AL014_12950 2600454..2600828 - 375 AOM17116 conjugal transfer protein orf23
AL014_12955 2600841..2601155 - 315 AOM17117 conjugal transfer protein orf23
AL014_12960 2601268..2604495 - 3228 AOM17118 cell surface protein -
AL014_12965 2604912..2606078 - 1167 AOM17119 recombinase -


Host bacterium


ID   270 Element type   ICE (Integrative and conjugative element)
Element name   ICE_EfmISMMSVRE1_rpsI GenBank   CP012430
Element size   3130373 bp Coordinate of oriT [Strand]   56381..56423 [+]
Host bacterium   Enterococcus faecium strain ISMMS_VRE_1 Coordinate of element   2539659..2604823

Cargo genes


Drug resistance gene   tet(M)
Virulence gene   psaA, fss3
Metal resistance gene   -
Degradation gene   -
Symbiosis gene   -
Anti-CRISPR   AcrIIA9, AcrIIA14