Detailed information of auxiliary protein

Auxiliary protein


ID   303 GenBank   AAB60030
Name   Int_Tn916  experimental UniProt ID   P22886
Length   405 a.a. PDB ID   1B69, 1BB8, 1TN9, 2BB8
Note   Int apparently plays a dual role in the movement of the transposon from the donor to the recipient. Integrase;Accessory protein

  Protein sequence


Download         Length: 405 a.a.        Molecular weight: 47049.93 Da        Isoelectric Point: 9.8019

>AAB60030.1 ORF2 [Enterococcus faecalis]
MSEKRRDNRGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKLVATDRVPAGKRDCISLREKIAELQKD
IHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNTETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSE
NGYAYQTINNYKRSLKASFYIAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYS
KNYDEILILLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVEEAYQ
AFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNEDKLPHITPHSLRHTFC
TNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMKRLNKEKQQERLVA

  Protein domains


Predicted by InterproScan

(190-383)

(1-71)

  Protein structure


Source ID Structure
PDB 1B69
PDB 1BB8
PDB 1TN9
PDB 2BB8
AlphaFold DB P22886

  Reference


[1] Rocco JM et al. (2006) The integrase of the conjugative transposon Tn916 directs strand- and sequence-specific cleavage of the origin of conjugal transfer, oriT, by the endonuclease Orf20. J Bacteriol. 188(6):2207-13. [PMID:16513750]