oriTDB
Information of T4CP
ID 7
Name TrwB_R388 experimental
SecReT4 accesion number _
GenBank accession number FAA00040
Family TrwB/TraD
Length 507 aa
UniProt ID Q04230
PDB ID 1E9R, 1E9S, 1GKI, 1GL6, 1GL7
Pfam TrwB_AAD_bind [PF10412.8], Evalue: 5.90E-97, Aligned region: 109..491
TraG-D_C [PF12696.6], Evalue: 2.70E-21, Aligned region: 350..472
T4SS-DNA_transf [PF02534.13], Evalue: 1.50E-12, Aligned region: 297..489
Note Type IV Secretion System Coupling Protein
Protein sequence [Download] MHPDDQRKVSAGIVIVLPLIFWITAVQKTEVLGSPKLLALWELMKLTPQKPILLLSALGG
LAVGVLFVWLLNSVGQGEFGGAPFKRFLRGTRIVSGGKLKRMTREKAKQVTVAGVPMPRD
AEPRHLLVNGATGTGKSVLLRELAYTGLLRGDRMVIVDPNGDMLSKFGRDKDIILNPYDQ
RTKGWSFFNEIRNDYDWQRYALSVVPRGKTDEAEEWASYGRLLLRETAKKLALIGTPSMR
ELFHWTTIATFDDLRGFLEGTLAESLFAGSNEASKALTSARFVLSDKLPEHVTMPDGDFS
IRSWLEDPNGGNLFITWREDMGPALRPLISAWVDVVCTSILSLPEEPKRRLWLFIDELAS
LEKLASLADALTKGRKAGLRVVAGLQSTSQLDDVYGVKEAQTLRASFRSLVVLGGSRTDP
KTNEDMSLSLGEHEVERDRYSKNTGKHHSTGRALERVRERVVMPAEIANLPDLTAYVGFA
GNRPIAKVPLEIKQFANRQPAFVEGTI

Reference
[1] Llosa M et al (1994) Genetic organization of the conjugal DNA processing region of the IncW plasmid R388. J Mol Biol. 235(2):448-64. [PMID:8289274]
[2] de la Cruz F et al (2010) Conjugative DNA metabolism in Gram-negative bacteria. FEMS Microbiol Rev. 34(1):18-40. [PMID:19919603]
[3] Fernández-López R et al (2006) Dynamics of the IncW genetic backbone imply general trends in conjugative plasmid evolution. FEMS Microbiol Rev. 30(6):942-66. [PMID:17026718]
[4] Cabezón E et al (1994) Requirements for mobilization of plasmids RSF1010 and ColE1 by the IncW plasmid R388: trwB and RP4 traG are interchangeable. J Bacteriol. 176(14):4455-8. [PMID:8021231]