oriTDB
Information of T4CP
ID 1
Name TraG_RP4 experimental
SecReT4 accesion number _
GenBank accession number CAA38334
Family VirD4/TraG
Length 635 aa
UniProt ID Q00185
PDB ID _
Pfam T4SS-DNA_transf [PF02534.13], Evalue: 2.20E-174, Aligned region: 120..624
TraG-D_C [PF12696.6], Evalue: 2.70E-31, Aligned region: 443..568
TrwB_AAD_bind [PF10412.8], Evalue: 1.80E-23, Aligned region: 175..575
Note conjugal transfer coupling protein TraG
Protein sequence [Download] MKNRNNAVGPQIRAKKPKASKTVPILAGLSLGAGLQTATQYFAHSFQYQAGLGWNINHVY
TPWSILQWAGKWYGQYPDDFMRAASMGMVVSTVGLLGTAVTQMVKANTGKANDYLHGSAR
WADKKDIQAAGLLPRPRTVVELVSGKHPPTSSGVYVGGWQDKDGKFHYLRHNGPEHVLTY
APTRSGKGVGLVVPTLLSWAHSAVITDLKGELWALTAGWRKKHARNKVVRFEPASAQGSA
CWNPLDEIRLGTEYEVGDVQNLATLIVDPDGKGLESHWQKTSQALLVGVILHALYKAKNE
GTPATLPSVDGMLADPNRDVGELWMEMTTYGHVDGQNHPAVGSAARDMMDRPEEESGSVL
STAKSYLALYRDPVVARNVSKSDFRIKQLMHHDDPVSLFIVTQPNDKARLRPLVRVMVNM
IVRLLADKMDFENGRPVAHYKHRLLMMLDEFPSLGKLEILQESLAFVAGYGIKCYLICQD
INQLKSRETGYGHDESITSNCHVQNAYPPNRVETAEHLSKLTGTTTIVKEQITTSGRRTS
ALLGNVSRTFQEVQRPLLTPDECLRMPGPKKSADGSIEEAGDMVVYVAGYPAIYGKQPLY
FKDPIFQARAAVPAPKVSDKLIQTATVEEGEGITI

Reference
[1] Grahn AM et al (2000) Components of the RP4 Conjugative Transfer Apparatus Form an Envelope Structure Bridging Inner and Outer Membranes of Donor Cells: Implications for Related Macromolecule Transport Systems. J Bacteriol. 182(6):1564-74. [PMID:10692361]
[2] Cabezón E et al (1994) Requirements for mobilization of plasmids RSF1010 and ColE1 by the IncW plasmid R388: trwB and RP4 traG are interchangeable. J Bacteriol. 176(14):4455-8. [PMID:8021231]
[3] Hamilton CM et al (2000) TraG from RP4 and TraG and VirD4 from Ti plasmids confer relaxosome specificity to the conjugal transfer system of pTiC58. J Bacteriol. 182(6):1541-8. [PMID:10692358]
[4] Gomis-Rüth FX et al (2004) Coupling factors in macromolecular type-IV secretion machineries. Curr Pharm Des. 10(13):1551-65. [PMID:15134575]