oriTDB
Auxiliary DNA-binding protein(s) of the relaxosome
ID 13
Name TrwA_R388 experimental
GenBank accession number YP_009182121
Length 121 aa
UniProt ID Q04229
PDB ID _
Pfam _
Note TrwA, together with TrwC and plasmid R388 oriT, forms a stable nucleoprotein structure, the relaxosome
Protein sequence [Download] MALGDPIQVRLSPEKQALLEDEAARKGKRLATYLRELLESENDLQGELAALRREVVSLHH
VIEDLADTGLRSDQSGPGQNAVQIETLLLLRAIAGPERMKPVKGELKRLGIEVWTPEGKE
D

Reference
[1] Revilla C et al (2008) Different pathways to acquiring resistance genes illustrated by the recent evolution of IncW plasmids. Antimicrob Agents Chemother. 52(4):1472-80. [PMID:18268088]
[2] Llosa M et al (1994) Genetic organization of the conjugal DNA processing region of the IncW plasmid R388. J Mol Biol. 235(2):448-64. [PMID:8289274]
[3] de la Cruz F et al (2010) Conjugative DNA metabolism in Gram-negative bacteria. FEMS Microbiol Rev. 34(1):18-40. [PMID:19919603]
[4] Fernández-López R et al (2006) Dynamics of the IncW genetic backbone imply general trends in conjugative plasmid evolution. FEMS Microbiol Rev. 30(6):942-66. [PMID:17026718]