Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/- |
Location | 3540449..3541103 | Replicon | chromosome |
Accession | NZ_CP027723 | ||
Organism | Pseudomonas orientalis strain 8B |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | C4J98_RS15815 | Protein ID | WP_124433181.1 |
Coordinates | 3540449..3540799 (+) | Length | 117 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | C4J98_RS15820 | Protein ID | WP_124433182.1 |
Coordinates | 3540789..3541103 (+) | Length | 105 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C4J98_RS15805 | 3537209..3538741 | + | 1533 | WP_025858974.1 | NADH-quinone oxidoreductase subunit M | - |
C4J98_RS15810 | 3538749..3540212 | + | 1464 | WP_124433180.1 | NADH-quinone oxidoreductase subunit NuoN | - |
C4J98_RS15815 | 3540449..3540799 | + | 351 | WP_124433181.1 | toxin | Toxin |
C4J98_RS15820 | 3540789..3541103 | + | 315 | WP_124433182.1 | transcriptional regulator | Antitoxin |
C4J98_RS15825 | 3541331..3542083 | - | 753 | WP_124433183.1 | outer membrane beta-barrel protein | - |
C4J98_RS15830 | 3542315..3542551 | + | 237 | WP_057721776.1 | hypothetical protein | - |
C4J98_RS15835 | 3542595..3542789 | - | 195 | WP_065884943.1 | hypothetical protein | - |
C4J98_RS15840 | 3542804..3542983 | - | 180 | WP_057721774.1 | hypothetical protein | - |
C4J98_RS15845 | 3543098..3543619 | + | 522 | WP_124433184.1 | DUF3087 domain-containing protein | - |
C4J98_RS15850 | 3543647..3545011 | - | 1365 | WP_124433185.1 | MFS transporter | - |
C4J98_RS15855 | 3545209..3546090 | - | 882 | WP_124433186.1 | Dyp-type peroxidase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 13789.73 Da Isoelectric Point: 9.7332
>T99997 WP_124433181.1 NZ_CP027723:3540449-3540799 [Pseudomonas orientalis]
MDALFIELPPFERHRKDYLSDELFHGFQQELMKNPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHELSDLTPQHKKTLKHMLDREIKARTHNET
MDALFIELPPFERHRKDYLSDELFHGFQQELMKNPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHELSDLTPQHKKTLKHMLDREIKARTHNET
Download Length: 351 bp
>T99997 NZ_CP027723:3540449-3540799 [Pseudomonas orientalis]
ATGGATGCTCTATTTATCGAACTGCCGCCCTTCGAGCGGCATCGCAAGGACTATTTGAGTGACGAGCTTTTCCACGGTTT
TCAACAAGAGCTGATGAAAAACCCGGAAGCGGGAGACGTGATCGAGGGAACGGGAGGGTTACGCAAGGTTCGCTTCGTCG
ATGAGCGACGAAACAAAGGCAAGCGCGGTGGCCTGCGGGTCATTTACTACTGGTGGTCAGGCGGCACGCAATTCTGGTTA
TTCACCTTGTACGGCAAGCACGAACTGAGCGACCTGACACCACAACACAAGAAAACCCTAAAACACATGCTGGACAGGGA
AATCAAAGCGAGAACACACAATGAAACGTGA
ATGGATGCTCTATTTATCGAACTGCCGCCCTTCGAGCGGCATCGCAAGGACTATTTGAGTGACGAGCTTTTCCACGGTTT
TCAACAAGAGCTGATGAAAAACCCGGAAGCGGGAGACGTGATCGAGGGAACGGGAGGGTTACGCAAGGTTCGCTTCGTCG
ATGAGCGACGAAACAAAGGCAAGCGCGGTGGCCTGCGGGTCATTTACTACTGGTGGTCAGGCGGCACGCAATTCTGGTTA
TTCACCTTGTACGGCAAGCACGAACTGAGCGACCTGACACCACAACACAAGAAAACCCTAAAACACATGCTGGACAGGGA
AATCAAAGCGAGAACACACAATGAAACGTGA
Antitoxin
Download Length: 105 a.a. Molecular weight: 11763.55 Da Isoelectric Point: 10.3437
>AT99997 WP_124433182.1 NZ_CP027723:3540789-3541103 [Pseudomonas orientalis]
MKREIFSELVEGFDALADERQGKITLRTHKAQLNKLDPLTAEEVVAVRQQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQAVTLIRLVARFPETVAQLAALG
MKREIFSELVEGFDALADERQGKITLRTHKAQLNKLDPLTAEEVVAVRQQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQAVTLIRLVARFPETVAQLAALG
Download Length: 315 bp
>AT99997 NZ_CP027723:3540789-3541103 [Pseudomonas orientalis]
ATGAAACGTGAAATTTTTTCAGAACTGGTCGAAGGCTTCGACGCGCTGGCCGACGAACGTCAGGGCAAAATCACCCTGCG
CACCCATAAGGCGCAGCTCAACAAACTCGACCCCCTCACAGCTGAAGAAGTGGTTGCAGTACGTCAGCAGCTCAACCTCT
CCCGGTCGGTATTCGCCATGTACCTGCGTACCAACACCCGGACCCTGGAAAACTGGGAACAAGGCCGGGCCAAGCCAAAT
GCACAGGCAGTCACGCTGATACGGCTGGTGGCGCGTTTTCCCGAGACCGTGGCGCAACTGGCCGCACTGGGCTGA
ATGAAACGTGAAATTTTTTCAGAACTGGTCGAAGGCTTCGACGCGCTGGCCGACGAACGTCAGGGCAAAATCACCCTGCG
CACCCATAAGGCGCAGCTCAACAAACTCGACCCCCTCACAGCTGAAGAAGTGGTTGCAGTACGTCAGCAGCTCAACCTCT
CCCGGTCGGTATTCGCCATGTACCTGCGTACCAACACCCGGACCCTGGAAAACTGGGAACAAGGCCGGGCCAAGCCAAAT
GCACAGGCAGTCACGCTGATACGGCTGGTGGCGCGTTTTCCCGAGACCGTGGCGCAACTGGCCGCACTGGGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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