Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 3540449..3541103 Replicon chromosome
Accession NZ_CP027723
Organism Pseudomonas orientalis strain 8B

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag C4J98_RS15815 Protein ID WP_124433181.1
Coordinates 3540449..3540799 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag C4J98_RS15820 Protein ID WP_124433182.1
Coordinates 3540789..3541103 (+) Length 105 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J98_RS15805 3537209..3538741 + 1533 WP_025858974.1 NADH-quinone oxidoreductase subunit M -
C4J98_RS15810 3538749..3540212 + 1464 WP_124433180.1 NADH-quinone oxidoreductase subunit NuoN -
C4J98_RS15815 3540449..3540799 + 351 WP_124433181.1 toxin Toxin
C4J98_RS15820 3540789..3541103 + 315 WP_124433182.1 transcriptional regulator Antitoxin
C4J98_RS15825 3541331..3542083 - 753 WP_124433183.1 outer membrane beta-barrel protein -
C4J98_RS15830 3542315..3542551 + 237 WP_057721776.1 hypothetical protein -
C4J98_RS15835 3542595..3542789 - 195 WP_065884943.1 hypothetical protein -
C4J98_RS15840 3542804..3542983 - 180 WP_057721774.1 hypothetical protein -
C4J98_RS15845 3543098..3543619 + 522 WP_124433184.1 DUF3087 domain-containing protein -
C4J98_RS15850 3543647..3545011 - 1365 WP_124433185.1 MFS transporter -
C4J98_RS15855 3545209..3546090 - 882 WP_124433186.1 Dyp-type peroxidase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 117 a.a.        Molecular weight: 13789.73 Da        Isoelectric Point: 9.7332

>T99997 WP_124433181.1 NZ_CP027723:3540449-3540799 [Pseudomonas orientalis]
MDALFIELPPFERHRKDYLSDELFHGFQQELMKNPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHELSDLTPQHKKTLKHMLDREIKARTHNET

Download         Length: 351 bp

>T99997 NZ_CP027723:3540449-3540799 [Pseudomonas orientalis]
ATGGATGCTCTATTTATCGAACTGCCGCCCTTCGAGCGGCATCGCAAGGACTATTTGAGTGACGAGCTTTTCCACGGTTT
TCAACAAGAGCTGATGAAAAACCCGGAAGCGGGAGACGTGATCGAGGGAACGGGAGGGTTACGCAAGGTTCGCTTCGTCG
ATGAGCGACGAAACAAAGGCAAGCGCGGTGGCCTGCGGGTCATTTACTACTGGTGGTCAGGCGGCACGCAATTCTGGTTA
TTCACCTTGTACGGCAAGCACGAACTGAGCGACCTGACACCACAACACAAGAAAACCCTAAAACACATGCTGGACAGGGA
AATCAAAGCGAGAACACACAATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11763.55 Da        Isoelectric Point: 10.3437

>AT99997 WP_124433182.1 NZ_CP027723:3540789-3541103 [Pseudomonas orientalis]
MKREIFSELVEGFDALADERQGKITLRTHKAQLNKLDPLTAEEVVAVRQQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQAVTLIRLVARFPETVAQLAALG

Download         Length: 315 bp

>AT99997 NZ_CP027723:3540789-3541103 [Pseudomonas orientalis]
ATGAAACGTGAAATTTTTTCAGAACTGGTCGAAGGCTTCGACGCGCTGGCCGACGAACGTCAGGGCAAAATCACCCTGCG
CACCCATAAGGCGCAGCTCAACAAACTCGACCCCCTCACAGCTGAAGAAGTGGTTGCAGTACGTCAGCAGCTCAACCTCT
CCCGGTCGGTATTCGCCATGTACCTGCGTACCAACACCCGGACCCTGGAAAACTGGGAACAAGGCCGGGCCAAGCCAAAT
GCACAGGCAGTCACGCTGATACGGCTGGTGGCGCGTTTTCCCGAGACCGTGGCGCAACTGGCCGCACTGGGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References