Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 2423601..2424194 Replicon chromosome
Accession NZ_CP027719
Organism Pseudomonas chlororaphis subsp. aureofaciens strain P2

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag C4K14_RS11390 Protein ID WP_096373593.1
Coordinates 2423916..2424194 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag C4K14_RS11385 Protein ID WP_124303178.1
Coordinates 2423601..2423906 (-) Length 102 a.a.

Genomic Context


C4K14_RS11345C4K14_RS11350C4K14_RS11355C4K14_RS11360C4K14_RS11365C4K14_RS11375C4K14_RS11400C4K14_RS11405C4K14_RS11415C4K14_RS11420C4K14_RS11425C4K14_RS11370C4K14_RS11380C4K14_RS11385C4K14_RS11390C4K14_RS11395C4K14_RS11410
Location: 2418808..2419017 (210 bp)
Type: Others
Protein ID: WP_124303186.1
Location: 2419063..2419305 (243 bp)
Type: Others
Protein ID: WP_124303185.1
Location: 2419329..2419559 (231 bp)
Type: Others
Protein ID: WP_124303184.1
Location: 2419804..2420115 (312 bp)
Type: Others
Protein ID: WP_124303183.1
Location: 2420142..2420381 (240 bp)
Type: Others
Protein ID: WP_124303182.1
Location: 2421684..2422157 (474 bp)
Type: Others
Protein ID: WP_124303180.1
Location: 2425222..2426043 (822 bp)
Type: Others
Protein ID: WP_124313167.1
Location: 2426083..2426808 (726 bp)
Type: Others
Protein ID: WP_124303175.1
Location: 2427650..2427805 (156 bp)
Type: Others
Protein ID: WP_124303173.1
Location: 2427878..2428186 (309 bp)
Type: Others
Protein ID: WP_124303172.1
Location: 2428186..2428980 (795 bp)
Type: Others
Protein ID: WP_124303171.1
Location: 2420427..2421455 (1029 bp)
Type: Others
Protein ID: WP_124303181.1
Location: 2422218..2423447 (1230 bp)
Type: Others
Protein ID: WP_124303179.1
Location: 2423601..2423906 (306 bp)
Type: Antitoxin
Protein ID: WP_124303178.1
Location: 2423916..2424194 (279 bp)
Type: Toxin
Protein ID: WP_096373593.1
Location: 2424320..2424745 (426 bp)
Type: Others
Protein ID: WP_124303177.1
Location: 2427105..2427533 (429 bp)
Type: Others
Protein ID: WP_124303174.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
C4K14_RS113452418808..2419017+210WP_124303186.1hypothetical protein-
C4K14_RS113502419063..2419305+243WP_124303185.1hypothetical protein-
C4K14_RS113552419329..2419559+231WP_124303184.1hypothetical protein-
C4K14_RS113602419804..2420115+312WP_124303183.1hypothetical protein-
C4K14_RS113652420142..2420381+240WP_124303182.1hypothetical protein-
C4K14_RS113702420427..2421455-1029WP_124303181.1virulence RhuM family protein-
C4K14_RS113752421684..2422157+474WP_124303180.1hypothetical protein-
C4K14_RS113802422218..2423447-1230WP_124303179.1hypothetical protein-
C4K14_RS113852423601..2423906-306WP_124303178.1HigA family addiction module antidote proteinAntitoxin
C4K14_RS113902423916..2424194-279WP_096373593.1type II toxin-antitoxin system RelE/ParE family toxinToxin
C4K14_RS113952424320..2424745-426WP_124303177.1topoisomerase DNA-binding C4 zinc finger domain-containing protein-
C4K14_RS114002425222..2426043+822WP_124313167.1hypothetical protein-
C4K14_RS114052426083..2426808+726WP_124303175.1hypothetical protein-
C4K14_RS114102427105..2427533-429WP_124303174.1Arc family DNA-binding protein-
C4K14_RS114152427650..2427805+156WP_124303173.1Arc family DNA-binding protein-
C4K14_RS114202427878..2428186+309WP_124303172.1DUF3077 domain-containing protein-
C4K14_RS114252428186..2428980+795WP_124303171.1phage antirepressor KilAC domain-containing protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--2417693..243318915496


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-92)

Antitoxin

(6-83)


Sequences


Toxin        


Download         Length: 93 a.a.        Molecular weight: 10342.78 Da        Isoelectric Point: 8.5136

>T99970 WP_096373593.1 NZ_CP027719:c2424194-2423916 [Pseudomonas chlororaphis subsp. aureofaciens]
MIISFGCDETESLYRTGSSRRWVGILSVAQRKLTMLDAATSIQDLKSPPGNRLEALQGNRKGQHSIRINDQFRICFIWGA
YGPESVAIVDYH

Download         Length: 279 bp

>T99970 NZ_CP027719:c2424194-2423916 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGATCATAAGCTTTGGCTGCGACGAGACAGAAAGCCTCTACAGAACAGGGTCCTCCCGGAGATGGGTGGGAATCCTTTC
GGTCGCACAAAGAAAACTGACCATGCTCGATGCAGCAACAAGCATTCAGGATCTGAAATCGCCGCCTGGCAATCGGCTGG
AAGCGCTACAAGGGAACCGAAAGGGTCAACACAGCATCCGAATTAATGACCAGTTCAGAATTTGCTTCATCTGGGGTGCG
TATGGGCCAGAAAGCGTTGCGATTGTAGACTACCACTGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11168.70 Da        Isoelectric Point: 6.2108

>AT99970 WP_124303178.1 NZ_CP027719:c2423906-2423601 [Pseudomonas chlororaphis subsp. aureofaciens]
VFTNGMRPVHPGEILREEYLHPMDLSPTALAKLLNVSAPTVNDIVRGRRNISADVALRLAACFDTSPQFWANLQSAYDLR
KAEIDHGAEIAQQVQRAPECA

Download         Length: 306 bp

>AT99970 NZ_CP027719:c2423906-2423601 [Pseudomonas chlororaphis subsp. aureofaciens]
GTGTTTACTAACGGTATGCGCCCTGTACATCCGGGCGAAATTCTCAGGGAAGAGTATCTCCATCCCATGGATCTTTCTCC
AACAGCTCTTGCGAAGCTGTTGAATGTGTCCGCGCCTACAGTCAATGACATTGTACGTGGCCGCCGCAATATCAGTGCAG
ACGTAGCTCTACGCTTGGCTGCTTGTTTTGATACGAGCCCACAGTTCTGGGCGAATCTTCAGTCCGCGTATGACCTGCGG
AAAGCAGAAATTGACCATGGTGCTGAAATTGCTCAGCAGGTTCAACGCGCACCAGAATGTGCCTGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References