Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
Location | 2423601..2424194 | Replicon | chromosome |
Accession | NZ_CP027719 | ||
Organism | Pseudomonas chlororaphis subsp. aureofaciens strain P2 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | C4K14_RS11390 | Protein ID | WP_096373593.1 |
Coordinates | 2423916..2424194 (-) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | graA | Uniprot ID | - |
Locus tag | C4K14_RS11385 | Protein ID | WP_124303178.1 |
Coordinates | 2423601..2423906 (-) | Length | 102 a.a. |
Genomic Context
Location: 2418808..2419017 (210 bp)
Type: Others
Protein ID: WP_124303186.1
Type: Others
Protein ID: WP_124303186.1
Location: 2419063..2419305 (243 bp)
Type: Others
Protein ID: WP_124303185.1
Type: Others
Protein ID: WP_124303185.1
Location: 2419329..2419559 (231 bp)
Type: Others
Protein ID: WP_124303184.1
Type: Others
Protein ID: WP_124303184.1
Location: 2419804..2420115 (312 bp)
Type: Others
Protein ID: WP_124303183.1
Type: Others
Protein ID: WP_124303183.1
Location: 2420142..2420381 (240 bp)
Type: Others
Protein ID: WP_124303182.1
Type: Others
Protein ID: WP_124303182.1
Location: 2421684..2422157 (474 bp)
Type: Others
Protein ID: WP_124303180.1
Type: Others
Protein ID: WP_124303180.1
Location: 2425222..2426043 (822 bp)
Type: Others
Protein ID: WP_124313167.1
Type: Others
Protein ID: WP_124313167.1
Location: 2426083..2426808 (726 bp)
Type: Others
Protein ID: WP_124303175.1
Type: Others
Protein ID: WP_124303175.1
Location: 2427650..2427805 (156 bp)
Type: Others
Protein ID: WP_124303173.1
Type: Others
Protein ID: WP_124303173.1
Location: 2427878..2428186 (309 bp)
Type: Others
Protein ID: WP_124303172.1
Type: Others
Protein ID: WP_124303172.1
Location: 2428186..2428980 (795 bp)
Type: Others
Protein ID: WP_124303171.1
Type: Others
Protein ID: WP_124303171.1
Location: 2420427..2421455 (1029 bp)
Type: Others
Protein ID: WP_124303181.1
Type: Others
Protein ID: WP_124303181.1
Location: 2422218..2423447 (1230 bp)
Type: Others
Protein ID: WP_124303179.1
Type: Others
Protein ID: WP_124303179.1
Location: 2423601..2423906 (306 bp)
Type: Antitoxin
Protein ID: WP_124303178.1
Type: Antitoxin
Protein ID: WP_124303178.1
Location: 2423916..2424194 (279 bp)
Type: Toxin
Protein ID: WP_096373593.1
Type: Toxin
Protein ID: WP_096373593.1
Location: 2424320..2424745 (426 bp)
Type: Others
Protein ID: WP_124303177.1
Type: Others
Protein ID: WP_124303177.1
Location: 2427105..2427533 (429 bp)
Type: Others
Protein ID: WP_124303174.1
Type: Others
Protein ID: WP_124303174.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C4K14_RS11345 | 2418808..2419017 | + | 210 | WP_124303186.1 | hypothetical protein | - |
C4K14_RS11350 | 2419063..2419305 | + | 243 | WP_124303185.1 | hypothetical protein | - |
C4K14_RS11355 | 2419329..2419559 | + | 231 | WP_124303184.1 | hypothetical protein | - |
C4K14_RS11360 | 2419804..2420115 | + | 312 | WP_124303183.1 | hypothetical protein | - |
C4K14_RS11365 | 2420142..2420381 | + | 240 | WP_124303182.1 | hypothetical protein | - |
C4K14_RS11370 | 2420427..2421455 | - | 1029 | WP_124303181.1 | virulence RhuM family protein | - |
C4K14_RS11375 | 2421684..2422157 | + | 474 | WP_124303180.1 | hypothetical protein | - |
C4K14_RS11380 | 2422218..2423447 | - | 1230 | WP_124303179.1 | hypothetical protein | - |
C4K14_RS11385 | 2423601..2423906 | - | 306 | WP_124303178.1 | HigA family addiction module antidote protein | Antitoxin |
C4K14_RS11390 | 2423916..2424194 | - | 279 | WP_096373593.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
C4K14_RS11395 | 2424320..2424745 | - | 426 | WP_124303177.1 | topoisomerase DNA-binding C4 zinc finger domain-containing protein | - |
C4K14_RS11400 | 2425222..2426043 | + | 822 | WP_124313167.1 | hypothetical protein | - |
C4K14_RS11405 | 2426083..2426808 | + | 726 | WP_124303175.1 | hypothetical protein | - |
C4K14_RS11410 | 2427105..2427533 | - | 429 | WP_124303174.1 | Arc family DNA-binding protein | - |
C4K14_RS11415 | 2427650..2427805 | + | 156 | WP_124303173.1 | Arc family DNA-binding protein | - |
C4K14_RS11420 | 2427878..2428186 | + | 309 | WP_124303172.1 | DUF3077 domain-containing protein | - |
C4K14_RS11425 | 2428186..2428980 | + | 795 | WP_124303171.1 | phage antirepressor KilAC domain-containing protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 2417693..2433189 | 15496 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10342.78 Da Isoelectric Point: 8.5136
>T99970 WP_096373593.1 NZ_CP027719:c2424194-2423916 [Pseudomonas chlororaphis subsp. aureofaciens]
MIISFGCDETESLYRTGSSRRWVGILSVAQRKLTMLDAATSIQDLKSPPGNRLEALQGNRKGQHSIRINDQFRICFIWGA
YGPESVAIVDYH
MIISFGCDETESLYRTGSSRRWVGILSVAQRKLTMLDAATSIQDLKSPPGNRLEALQGNRKGQHSIRINDQFRICFIWGA
YGPESVAIVDYH
Download Length: 279 bp
>T99970 NZ_CP027719:c2424194-2423916 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGATCATAAGCTTTGGCTGCGACGAGACAGAAAGCCTCTACAGAACAGGGTCCTCCCGGAGATGGGTGGGAATCCTTTC
GGTCGCACAAAGAAAACTGACCATGCTCGATGCAGCAACAAGCATTCAGGATCTGAAATCGCCGCCTGGCAATCGGCTGG
AAGCGCTACAAGGGAACCGAAAGGGTCAACACAGCATCCGAATTAATGACCAGTTCAGAATTTGCTTCATCTGGGGTGCG
TATGGGCCAGAAAGCGTTGCGATTGTAGACTACCACTGA
ATGATCATAAGCTTTGGCTGCGACGAGACAGAAAGCCTCTACAGAACAGGGTCCTCCCGGAGATGGGTGGGAATCCTTTC
GGTCGCACAAAGAAAACTGACCATGCTCGATGCAGCAACAAGCATTCAGGATCTGAAATCGCCGCCTGGCAATCGGCTGG
AAGCGCTACAAGGGAACCGAAAGGGTCAACACAGCATCCGAATTAATGACCAGTTCAGAATTTGCTTCATCTGGGGTGCG
TATGGGCCAGAAAGCGTTGCGATTGTAGACTACCACTGA
Antitoxin
Download Length: 102 a.a. Molecular weight: 11168.70 Da Isoelectric Point: 6.2108
>AT99970 WP_124303178.1 NZ_CP027719:c2423906-2423601 [Pseudomonas chlororaphis subsp. aureofaciens]
VFTNGMRPVHPGEILREEYLHPMDLSPTALAKLLNVSAPTVNDIVRGRRNISADVALRLAACFDTSPQFWANLQSAYDLR
KAEIDHGAEIAQQVQRAPECA
VFTNGMRPVHPGEILREEYLHPMDLSPTALAKLLNVSAPTVNDIVRGRRNISADVALRLAACFDTSPQFWANLQSAYDLR
KAEIDHGAEIAQQVQRAPECA
Download Length: 306 bp
>AT99970 NZ_CP027719:c2423906-2423601 [Pseudomonas chlororaphis subsp. aureofaciens]
GTGTTTACTAACGGTATGCGCCCTGTACATCCGGGCGAAATTCTCAGGGAAGAGTATCTCCATCCCATGGATCTTTCTCC
AACAGCTCTTGCGAAGCTGTTGAATGTGTCCGCGCCTACAGTCAATGACATTGTACGTGGCCGCCGCAATATCAGTGCAG
ACGTAGCTCTACGCTTGGCTGCTTGTTTTGATACGAGCCCACAGTTCTGGGCGAATCTTCAGTCCGCGTATGACCTGCGG
AAAGCAGAAATTGACCATGGTGCTGAAATTGCTCAGCAGGTTCAACGCGCACCAGAATGTGCCTGA
GTGTTTACTAACGGTATGCGCCCTGTACATCCGGGCGAAATTCTCAGGGAAGAGTATCTCCATCCCATGGATCTTTCTCC
AACAGCTCTTGCGAAGCTGTTGAATGTGTCCGCGCCTACAGTCAATGACATTGTACGTGGCCGCCGCAATATCAGTGCAG
ACGTAGCTCTACGCTTGGCTGCTTGTTTTGATACGAGCCCACAGTTCTGGGCGAATCTTCAGTCCGCGTATGACCTGCGG
AAAGCAGAAATTGACCATGGTGCTGAAATTGCTCAGCAGGTTCAACGCGCACCAGAATGTGCCTGA