Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4552366..4553020 Replicon chromosome
Accession NZ_CP027708
Organism Pseudomonas chlororaphis subsp. piscium strain ATCC 17411

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag C4K37_RS20450 Protein ID WP_124324922.1
Coordinates 4552366..4552716 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag C4K37_RS20455 Protein ID WP_124324923.1
Coordinates 4552706..4553020 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K37_RS20440 4549117..4550649 + 1533 WP_053279911.1 NADH-quinone oxidoreductase subunit M -
C4K37_RS20445 4550657..4552120 + 1464 WP_009049791.1 NADH-quinone oxidoreductase subunit NuoN -
C4K37_RS20450 4552366..4552716 + 351 WP_124324922.1 toxin Toxin
C4K37_RS20455 4552706..4553020 + 315 WP_124324923.1 transcriptional regulator Antitoxin
C4K37_RS20460 4553198..4554940 - 1743 WP_025804713.1 ABC transporter substrate-binding protein -
C4K37_RS20465 4554991..4555263 - 273 WP_025804714.1 DUF2160 domain-containing protein -
C4K37_RS20470 4555274..4556074 - 801 WP_007929618.1 carbohydrate ABC transporter permease -
C4K37_RS20475 4556086..4556952 - 867 WP_124324924.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13791.76 Da        Isoelectric Point: 9.4187

>T99906 WP_124324922.1 NZ_CP027708:4552366-4552716 [Pseudomonas chlororaphis subsp. piscium]
MDALFIELPPFQRHRQDYLDDELFRSLQLELLKAPEAGDLIEGVGGLRKIRFVDERRHKGKRGGIRVIYYWWSGGAQFWL
FTLYAKNEQNDLTSHQKKLLKQLLNREVEARTHHET

Download         Length: 351 bp

>T99906 NZ_CP027708:4552366-4552716 [Pseudomonas chlororaphis subsp. piscium]
ATGGACGCACTTTTTATTGAGCTGCCCCCGTTCCAACGCCATCGACAGGACTACCTGGACGACGAGCTTTTTCGTAGCTT
GCAGCTTGAATTGCTGAAAGCCCCCGAAGCCGGAGATCTCATCGAGGGAGTCGGTGGCTTGCGCAAGATCCGCTTTGTCG
ATGAGCGACGGCACAAGGGCAAACGCGGCGGGATCCGGGTGATTTATTACTGGTGGTCCGGAGGCGCCCAGTTCTGGCTC
TTCACCCTTTACGCAAAGAACGAGCAGAACGACCTGACATCCCATCAGAAAAAACTGCTCAAGCAACTGCTGAACAGAGA
AGTCGAGGCGAGAACCCATCATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11921.84 Da        Isoelectric Point: 10.7886

>AT99906 WP_124324923.1 NZ_CP027708:4552706-4553020 [Pseudomonas chlororaphis subsp. piscium]
MKRDIFSELVEGFDTLAKERQGKLTLRTHKVKLNALLPITAEEVLAVREQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQATTLIRLVQRFPDTVERLAALA

Download         Length: 315 bp

>AT99906 NZ_CP027708:4552706-4553020 [Pseudomonas chlororaphis subsp. piscium]
ATGAAACGTGACATCTTTTCCGAACTGGTCGAAGGTTTCGACACCCTGGCCAAAGAGCGCCAAGGCAAGCTCACGCTGCG
CACCCACAAGGTCAAGCTGAACGCACTGCTACCGATCACCGCTGAAGAAGTGCTGGCCGTGCGCGAACAGCTGAACCTGT
CCAGATCGGTATTTGCCATGTACCTGCGCACCAATACTCGGACCCTGGAGAACTGGGAGCAAGGACGGGCAAAACCCAAC
GCCCAGGCCACCACCCTGATCCGCCTGGTACAGCGTTTTCCCGATACGGTGGAGCGGCTGGCAGCCCTTGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References