Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 2204095..2204801 Replicon chromosome
Accession NZ_CP027663
Organism Acidiferrobacter sp. SPIII_3

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag C4901_RS11100 Protein ID WP_110137385.1
Coordinates 2204502..2204801 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag C4901_RS11095 Protein ID WP_110137384.1
Coordinates 2204095..2204499 (-) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4901_RS11080 2201749..2202126 + 378 WP_110137381.1 hypothetical protein -
C4901_RS11085 2202203..2202928 + 726 WP_110137382.1 hypothetical protein -
C4901_RS11090 2202998..2203723 + 726 WP_110137383.1 hypothetical protein -
C4901_RS11095 2204095..2204499 - 405 WP_110137384.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
C4901_RS11100 2204502..2204801 - 300 WP_110137385.1 type II toxin-antitoxin system MqsR family toxin Toxin
C4901_RS11105 2205118..2207727 - 2610 WP_145960702.1 hypothetical protein -
C4901_RS17320 2208500..2209222 - 723 WP_145960703.1 hypothetical protein -
C4901_RS11110 2209225..2209497 - 273 WP_110137387.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2181035..2237792 56757


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-98)

Antitoxin

Zinc finger, MqsA-type

(3-47)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 10864.64 Da        Isoelectric Point: 7.9339

>T99814 WP_110137385.1 NZ_CP027663:c2204801-2204502 [Acidiferrobacter sp. SPIII_3]
MEKRVPHCPLSVVKALVEAGQVRATASAFQGARGVGVFDLAGMCAVVMALSPAHFQKSMTTHADHRVWQDVYHARTNQAD
VYLKLTVIEDVLIVSFKEL

Download         Length: 300 bp

>T99814 NZ_CP027663:c2204801-2204502 [Acidiferrobacter sp. SPIII_3]
ATGGAGAAACGCGTTCCTCACTGTCCGCTCTCCGTGGTGAAGGCCTTGGTAGAGGCGGGGCAGGTGCGGGCCACGGCCAG
CGCCTTCCAGGGGGCGCGAGGGGTCGGGGTTTTTGATCTGGCGGGGATGTGCGCGGTTGTGATGGCGCTGTCGCCCGCCC
ACTTTCAGAAGAGCATGACCACACACGCCGATCATCGCGTCTGGCAAGACGTGTACCACGCCCGGACCAACCAAGCAGAC
GTGTACCTGAAGCTCACGGTGATCGAGGACGTGCTGATCGTGTCTTTTAAGGAGCTATGA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 14856.93 Da        Isoelectric Point: 6.2241

>AT99814 WP_110137384.1 NZ_CP027663:c2204499-2204095 [Acidiferrobacter sp. SPIII_3]
MKCPCCGAAELIPDTRDIPYTYKGETTTLVAVTGEFCPACGEIVLNREHGDRYSELLGQFQRQVNAAYVDPDYIARVRKK
LDLDQRQAAEIFGGGVNAFSRYENGKTKPSLALVKLLKVLDHHPDLLSEIRDGA

Download         Length: 405 bp

>AT99814 NZ_CP027663:c2204499-2204095 [Acidiferrobacter sp. SPIII_3]
ATGAAGTGTCCTTGCTGTGGCGCGGCGGAATTGATCCCCGACACGCGCGATATCCCCTACACCTACAAGGGCGAAACCAC
CACCCTTGTGGCGGTAACGGGCGAATTTTGTCCGGCCTGCGGCGAAATCGTCTTAAACCGCGAGCACGGCGACCGTTACA
GCGAATTGCTCGGACAGTTCCAGCGCCAGGTCAACGCAGCCTATGTCGATCCCGACTACATTGCCAGGGTTCGTAAGAAA
CTCGACCTGGATCAACGGCAGGCGGCGGAGATATTCGGGGGTGGAGTCAACGCCTTTTCGCGTTACGAGAACGGCAAGAC
CAAGCCGTCCTTGGCGCTGGTGAAACTCTTGAAGGTCTTGGACCATCACCCGGATCTCTTGAGCGAGATCCGCGACGGGG
CCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References