Detailed information of TA system TA099811

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mqsRA (relBE)/MqsR-MqsA
• Location: 1476991..1477682
• Replicon: chromosome
• Accession: NZ_CP027663
• Organism: Acidiferrobacter sp. SPIII_3

Toxin (Protein)

• Gene name: mqsR
• Uniprot ID: -
• Locus tag: C4901_RS07395
• Protein ID: WP_110138568.1
• Coordinates: 1477386..1477682 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: mqsA
• Uniprot ID: -
• Locus tag: C4901_RS07390
• Protein ID: WP_205736262.1
• Coordinates: 1476991..1477383 (-)
• Length: 131 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C4901_RS07360	1472025..1472450	-	426	WP_110136770.1	relaxase domain-containing protein	-
C4901_RS07365	1472988..1473335	+	348	WP_110136771.1	hypothetical protein	-
C4901_RS07370	1473417..1474142	+	726	WP_110136772.1	hypothetical protein	-
C4901_RS07375	1474213..1474923	+	711	WP_110136773.1	hypothetical protein	-
C4901_RS17265	1474953..1476134	+	1182	WP_145960652.1	hypothetical protein	-
C4901_RS07385	1476593..1476928	+	336	WP_145960653.1	hypothetical protein	-
C4901_RS18005	1476906..1477052	-	147	Protein_1455	type II toxin-antitoxin system MqsA family antitoxin	-
C4901_RS07390	1476991..1477383	-	393	WP_205736262.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
C4901_RS07395	1477386..1477682	-	297	WP_110138568.1	type II toxin-antitoxin system MqsR family toxin	Toxin
C4901_RS07400	1478486..1478779	-	294	WP_145960654.1	hypothetical protein	-
C4901_RS07405	1479103..1479480	-	378	WP_145960655.1	hypothetical protein	-
C4901_RS07410	1479625..1479975	-	351	WP_110136778.1	hypothetical protein	-
C4901_RS17270	1481110..1481406	+	297	WP_145960656.1	hypothetical protein	-
C4901_RS07420	1481357..1481842	+	486	WP_205736263.1	tyrosine-type recombinase/integrase	-
C4901_RS07425	1481846..1482034	+	189	WP_110136781.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	1461762..1480668	18906

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (2-97)

Antitoxin

• Antitoxin MqsA/HigA-2 (1-111)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 10761.58 Da
• Isoelectric Point: 6.8779

>T99811 WP_110138568.1 NZ_CP027663:c1477682-1477386 [Acidiferrobacter sp. SPIII_3]
MEKRTPHSSLAVVKTLVEAGMIRTTQTARVGAVALGFDLAGMIAVVMALESGDFYKSMTTHADHKIWQDVYRPHTAAGDV
YLKLIVIDDVLIVSFKEL

Nucleotide

• Length: 297 bp

>T99811 NZ_CP027663:c1477682-1477386 [Acidiferrobacter sp. SPIII_3]
ATGGAGAAACGGACCCCGCATAGCTCCCTGGCTGTCGTCAAGACCTTGGTCGAGGCCGGCATGATCCGCACGACGCAGAC
GGCACGGGTGGGGGCCGTGGCCTTGGGTTTTGACCTCGCGGGGATGATTGCGGTCGTGATGGCCCTGGAGTCAGGAGACT
TCTATAAGAGCATGACCACACATGCCGACCACAAGATCTGGCAGGATGTGTACAGGCCCCACACGGCGGCAGGTGATGTC
TATCTGAAACTGATCGTGATCGACGATGTGTTGATCGTATCGTTTAAGGAGTTGTGA

Antitoxin

Protein

• Length: 131 a.a.
• Molecular weight: 14341.42 Da
• Isoelectric Point: 8.2363

>AT99811 WP_205736262.1 NZ_CP027663:c1477383-1476991 [Acidiferrobacter sp. SPIII_3]
MKCPVCGGAELIPDTRDLPYTYKGETTTIPAVSGEFCPACGEAILESGESDRVMREMRAFSKEVNAAVVDPAFIVHVRKK
LALDQREAAEIFGGGVNAFSRYETGKTRPPSRGCRDLRRGRQCFLALRDR

Nucleotide

• Length: 393 bp

>AT99811 NZ_CP027663:c1477383-1476991 [Acidiferrobacter sp. SPIII_3]
ATGAAATGTCCCGTATGTGGCGGTGCGGAACTGATCCCTGACACCCGTGACCTGCCTTACACCTACAAGGGTGAGACCAC
TACCATCCCGGCGGTGTCGGGTGAGTTCTGTCCGGCATGCGGGGAGGCGATTCTCGAATCCGGCGAATCGGATCGCGTCA
TGCGCGAGATGAGGGCGTTTTCCAAGGAGGTCAATGCCGCTGTCGTTGATCCCGCCTTCATTGTCCATGTGCGCAAGAAG
CTCGCCCTTGATCAACGCGAGGCTGCCGAGATCTTCGGCGGGGGCGTCAATGCTTTCTCGCGCTACGAGACCGGTAAGAC
GAGACCGCCATCGCGAGGCTGCCGAGATCTTCGGCGGGGGCGTCAATGCTTTCTCGCGCTACGAGACCGGTAA