Detailed information of TA system TA098569

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ralRA/-
• Location: 596724..597095
• Replicon: chromosome
• Accession: NZ_CP027390
• Organism: Escherichia coli strain 2015C-4944

Toxin (Protein)

• Gene name: ralR
• Uniprot ID: A0A891STD1
• Locus tag: AX062_RS03190
• Protein ID: WP_042853000.1
• Coordinates: 596901..597095 (-)
• Length: 65 a.a.

Antitoxin (RNA)

Gene name	ralA
Locus tag	-
Coordinates	596724..596902 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AX062_RS03150	592167..592823	-	657	WP_000011658.1	carbon-nitrogen hydrolase family protein	-
AX062_RS03155	592925..593155	-	231	WP_000916763.1	DNA polymerase III subunit theta	-
AX062_RS03160	593294..593668	+	375	WP_000204699.1	CopC domain-containing protein YobA	-
AX062_RS03165	593672..594544	+	873	WP_000879280.1	copper homeostasis membrane protein CopD	-
AX062_RS03170	594557..594898	+	342	WP_000976492.1	YebY family protein	-
AX062_RS03175	595251..596366	-	1116	WP_001189092.1	phage integrase Arm DNA-binding domain-containing protein	-
AX062_RS03180	596332..596613	-	282	WP_001443927.1	excisionase	-
AX062_RS03185	596720..596908	-	189	WP_001356607.1	DUF1187 family protein	-
-	596724..596902	+	179	NuclAT_1	-	Antitoxin
-	596724..596902	+	179	NuclAT_1	-	Antitoxin
-	596724..596902	+	179	NuclAT_1	-	Antitoxin
-	596724..596902	+	179	NuclAT_1	-	Antitoxin
AX062_RS03190	596901..597095	-	195	WP_042853000.1	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	Toxin
AX062_RS03195	597152..597559	-	408	Protein_591	recombinase RecT	-
AX062_RS03205	598824..599228	-	405	Protein_593	recombinase RecT	-
AX062_RS03210	599221..601872	-	2652	WP_000105101.1	exodeoxyribonuclease VIII	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	nleG7'	589424..661668	72244

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Endodeoxyribonuclease toxin RalR (6-54)

Sequences

Toxin

Protein

• Length: 65 a.a.
• Molecular weight: 7019.87 Da
• Isoelectric Point: 8.6419

>T98569 WP_042853000.1 NZ_CP027390:c597095-596901 [Escherichia coli]
MRYDDVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV

Nucleotide

• Length: 195 bp

>T98569 NZ_CP027390:c597095-596901 [Escherichia coli]
ATGAGATATGACGATGTTAAACCATGTCCGTTTTGTGGTTGTCCATCTGTTACAGTGAAAGCAATTTCAGGATATTACCG
GGCAAAATGCAACGGATGCGAATCCCGAACTGGCTATGGTGGAAGTGAAAAAGAAGCACTCGAAAGATGGAATAAACGAA
CTACTGGAAATAATAATGGAGGTGTTCATGTATAA

Antitoxin

Nucleotide

• Length: 179 bp

>AT98569 NZ_CP027390:596724-596902 [Escherichia coli]
GAGGACAGAAGTTTCTCGCAATTAAAATTTATCAGCTTTACTTTCTGCTCTCTGGACACGCCTGCTTCTTTTTTCCCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAATTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCTTTTT
CAATAGTGGCAGTTATTTT

Structures

Antitoxin