Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | symER/SymE(toxin) |
Location | 4722312..4722724 | Replicon | chromosome |
Accession | NZ_CP027338 | ||
Organism | Escherichia coli strain 2014C-3051 |
Toxin (Protein)
Gene name | symE | Uniprot ID | A0A0F3WCK2 |
Locus tag | C6N28_RS25730 | Protein ID | WP_000132621.1 |
Coordinates | 4722312..4722653 (-) | Length | 114 a.a. |
Antitoxin (RNA)
Gene name | symR | ||
Locus tag | - | ||
Coordinates | 4722648..4722724 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C6N28_RS25715 | 4718322..4719734 | - | 1413 | WP_000199352.1 | PLP-dependent aminotransferase family protein | - |
C6N28_RS25720 | 4719911..4720075 | + | 165 | WP_000394276.1 | DUF1127 domain-containing protein | - |
C6N28_RS25725 | 4720172..4722265 | + | 2094 | WP_000648228.1 | DUF262 domain-containing protein | - |
C6N28_RS25730 | 4722312..4722653 | - | 342 | WP_000132621.1 | endoribonuclease SymE | Toxin |
- | 4722648..4722724 | + | 77 | NuclAT_27 | - | Antitoxin |
- | 4722648..4722724 | + | 77 | NuclAT_27 | - | Antitoxin |
- | 4722648..4722724 | + | 77 | NuclAT_27 | - | Antitoxin |
- | 4722648..4722724 | + | 77 | NuclAT_27 | - | Antitoxin |
- | 4722648..4722724 | + | 77 | NuclAT_28 | - | Antitoxin |
- | 4722648..4722724 | + | 77 | NuclAT_28 | - | Antitoxin |
- | 4722648..4722724 | + | 77 | NuclAT_28 | - | Antitoxin |
- | 4722648..4722724 | + | 77 | NuclAT_28 | - | Antitoxin |
C6N28_RS25735 | 4722874..4724643 | - | 1770 | WP_000110079.1 | restriction endonuclease subunit S | - |
C6N28_RS25740 | 4724643..4726112 | - | 1470 | WP_001341289.1 | type I restriction-modification system subunit M | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 114 a.a. Molecular weight: 12342.12 Da Isoelectric Point: 7.8218
>T98091 WP_000132621.1 NZ_CP027338:c4722653-4722312 [Escherichia coli]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPTAEESE
LMQSLRQVCKLSARKQKQVQDFIGVITGKQKVA
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPTAEESE
LMQSLRQVCKLSARKQKQVQDFIGVITGKQKVA
Download Length: 342 bp
>T98091 NZ_CP027338:c4722653-4722312 [Escherichia coli]
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGCTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACGGCGGTAGATGTCAAAGTAATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCACCGCCGAAGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAAAAGCAGGTGCAGGATTTTATTGGGGTAATTAC
CGGTAAACAGAAAGTCGCCTGA
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGCTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACGGCGGTAGATGTCAAAGTAATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCACCGCCGAAGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAAAAGCAGGTGCAGGATTTTATTGGGGTAATTAC
CGGTAAACAGAAAGTCGCCTGA
Antitoxin
Download Length: 77 bp
>AT98091 NZ_CP027338:4722648-4722724 [Escherichia coli]
AGTCATAACTGCTATTCTCCGATAATAGTGATTGTGATTAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT
AGTCATAACTGCTATTCTCCGATAATAGTGATTGTGATTAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|