97641

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 5296850..5297505 Replicon chromosome
Accession NZ_CP027218
Organism Pseudomonas sp. DTU12.3

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag C2E19_RS24245 Protein ID WP_129395408.1
Coordinates 5297161..5297505 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag C2E19_RS24240 Protein ID WP_129395407.1
Coordinates 5296850..5297164 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2E19_RS24215 5292175..5292693 - 519 WP_129395402.1 peptide-methionine (R)-S-oxide reductase MsrB -
C2E19_RS24220 5292846..5293556 + 711 WP_129395403.1 response regulator transcription factor -
C2E19_RS24225 5293553..5295064 + 1512 WP_129395404.1 HAMP domain-containing histidine kinase -
C2E19_RS24230 5295183..5295884 + 702 WP_129395405.1 hypothetical protein -
C2E19_RS24235 5296157..5296648 - 492 WP_129395406.1 RidA family protein -
C2E19_RS24240 5296850..5297164 - 315 WP_129395407.1 helix-turn-helix domain-containing protein Antitoxin
C2E19_RS24245 5297161..5297505 - 345 WP_129395408.1 toxin Toxin
C2E19_RS24250 5297622..5298509 - 888 WP_053123579.1 heme o synthase -
C2E19_RS24255 5298520..5298858 - 339 WP_129395409.1 cytochrome o ubiquinol oxidase subunit IV -
C2E19_RS24260 5298858..5299481 - 624 WP_129395410.1 cytochrome o ubiquinol oxidase subunit III -
C2E19_RS24265 5299485..5301515 - 2031 WP_129395411.1 cytochrome o ubiquinol oxidase subunit I -
C2E19_RS24270 5301519..5302460 - 942 WP_129395412.1 ubiquinol oxidase subunit II -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-94)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13462.27 Da        Isoelectric Point: 9.3726

>T97641 WP_129395408.1 NZ_CP027218:c5297505-5297161 [Pseudomonas sp. DTU12.3]
MRTVFFETTIFTANVGHYLTDDEYRELQDFLQGNTLAGDVMQRTGGFRKLRWADVRRGKGRRGGLRVLYYWLMNDGQFWM
FSIYDKDELENLTAEQEKALKRAIDRELKARGTP

Download         Length: 345 bp

>T97641 NZ_CP027218:c5297505-5297161 [Pseudomonas sp. DTU12.3]
ATGCGAACTGTCTTCTTTGAAACCACAATTTTTACCGCGAACGTTGGCCATTACCTAACGGACGATGAGTACCGAGAGCT
GCAGGACTTTCTGCAGGGTAATACGCTGGCTGGCGATGTGATGCAGCGAACGGGTGGCTTCCGAAAACTGCGCTGGGCCG
ATGTTCGTCGTGGCAAAGGTCGGCGAGGCGGCTTGCGGGTTCTTTATTATTGGCTTATGAATGATGGCCAGTTCTGGATG
TTTTCCATTTACGACAAAGATGAGCTTGAGAATCTGACCGCCGAGCAAGAAAAGGCGCTCAAGAGAGCGATTGATAGAGA
GTTAAAAGCACGAGGCACCCCATGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11885.85 Da        Isoelectric Point: 10.3048

>AT97641 WP_129395407.1 NZ_CP027218:c5297164-5296850 [Pseudomonas sp. DTU12.3]
MKKRDLFAELMQGVDEMAAQREGKITLRNTIVEDKPVPEVGAQEIVALRERLHMSQAVFAKRIRTSPSTLRNWEQEKSKP
NAQAALLIRLVEKFPDMVERLSAV

Download         Length: 315 bp

>AT97641 NZ_CP027218:c5297164-5296850 [Pseudomonas sp. DTU12.3]
ATGAAAAAACGCGACCTGTTTGCAGAGTTGATGCAGGGCGTTGATGAGATGGCAGCTCAACGCGAAGGCAAAATTACGTT
GCGTAATACAATCGTCGAGGACAAACCTGTCCCCGAGGTTGGCGCCCAGGAAATTGTCGCGCTACGGGAAAGGTTACATA
TGTCCCAAGCGGTTTTTGCCAAGCGAATCAGGACAAGCCCCAGCACCTTGAGAAACTGGGAGCAGGAGAAGTCGAAGCCC
AATGCTCAAGCAGCCTTGTTGATTCGTTTGGTTGAGAAATTCCCAGACATGGTCGAGCGTTTGAGCGCTGTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References