Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/RelE-HTH |
Location | 2368..2953 | Replicon | plasmid unnamed4 |
Accession | NZ_CP027186 | ||
Organism | Acinetobacter baumannii strain AR_0052 |
Toxin (Protein)
Gene name | higB | Uniprot ID | N8ZPD7 |
Locus tag | CSB68_RS20960 | Protein ID | WP_000897309.1 |
Coordinates | 2633..2953 (-) | Length | 107 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | CSB68_RS20955 | Protein ID | WP_000369782.1 |
Coordinates | 2368..2640 (-) | Length | 91 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CSB68_RS20940 | 28..774 | + | 747 | Protein_0 | hypothetical protein | - |
CSB68_RS20945 | 932..1363 | - | 432 | WP_000042163.1 | MarR family transcriptional regulator | - |
CSB68_RS20950 | 1370..1798 | - | 429 | WP_000105988.1 | organic hydroperoxide resistance protein | - |
CSB68_RS20955 | 2368..2640 | - | 273 | WP_000369782.1 | helix-turn-helix domain-containing protein | Antitoxin |
CSB68_RS20960 | 2633..2953 | - | 321 | WP_000897309.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
CSB68_RS20965 | 3140..3337 | - | 198 | WP_000476222.1 | hypothetical protein | - |
CSB68_RS20970 | 3404..3631 | - | 228 | WP_000921865.1 | hypothetical protein | - |
CSB68_RS20975 | 3729..3944 | - | 216 | WP_000071892.1 | cold-shock protein | - |
CSB68_RS20980 | 4278..4487 | - | 210 | WP_000069474.1 | hypothetical protein | - |
CSB68_RS20985 | 4480..4782 | - | 303 | WP_001129974.1 | XRE family transcriptional regulator | - |
CSB68_RS20990 | 4775..5131 | - | 357 | WP_000269904.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
CSB68_RS20995 | 5750..6178 | + | 429 | WP_000105988.1 | organic hydroperoxide resistance protein | - |
CSB68_RS21000 | 6185..6616 | + | 432 | WP_000042163.1 | MarR family transcriptional regulator | - |
CSB68_RS21005 | 6856..7374 | - | 519 | WP_000839337.1 | plasmid replication DNA-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..38505 | 38505 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 107 a.a. Molecular weight: 12209.01 Da Isoelectric Point: 7.9835
>T97585 WP_000897309.1 NZ_CP027186:c2953-2633 [Acinetobacter baumannii]
MLFIETSIFTKQIKELVSDEEYRQLQQDLLVQPDKGDLIKNGGGIRKVRCAQGNKGKSGGIRVIYYWVTEDDQIFFLVAY
PKSVKDNLTDKETSILRQLVKEQFHG
MLFIETSIFTKQIKELVSDEEYRQLQQDLLVQPDKGDLIKNGGGIRKVRCAQGNKGKSGGIRVIYYWVTEDDQIFFLVAY
PKSVKDNLTDKETSILRQLVKEQFHG
Download Length: 321 bp
>T97585 NZ_CP027186:c2953-2633 [Acinetobacter baumannii]
ATGTTATTCATTGAAACCAGTATTTTTACTAAGCAAATCAAAGAGCTTGTGAGTGATGAAGAGTATCGTCAGCTCCAGCA
AGATCTCTTGGTACAGCCTGATAAGGGCGACTTAATCAAGAATGGTGGTGGAATTCGTAAAGTACGTTGTGCTCAGGGCA
ATAAAGGCAAAAGTGGCGGTATCCGTGTGATCTATTATTGGGTTACAGAAGATGATCAGATCTTTTTCTTGGTGGCTTAT
CCAAAGTCTGTGAAAGATAATCTGACAGACAAAGAAACCTCGATTCTACGTCAATTAGTAAAGGAGCAATTTCATGGATA
A
ATGTTATTCATTGAAACCAGTATTTTTACTAAGCAAATCAAAGAGCTTGTGAGTGATGAAGAGTATCGTCAGCTCCAGCA
AGATCTCTTGGTACAGCCTGATAAGGGCGACTTAATCAAGAATGGTGGTGGAATTCGTAAAGTACGTTGTGCTCAGGGCA
ATAAAGGCAAAAGTGGCGGTATCCGTGTGATCTATTATTGGGTTACAGAAGATGATCAGATCTTTTTCTTGGTGGCTTAT
CCAAAGTCTGTGAAAGATAATCTGACAGACAAAGAAACCTCGATTCTACGTCAATTAGTAAAGGAGCAATTTCATGGATA
A
Antitoxin
Download Length: 91 a.a. Molecular weight: 10064.50 Da Isoelectric Point: 7.2045
>AT97585 WP_000369782.1 NZ_CP027186:c2640-2368 [Acinetobacter baumannii]
MDNNLFDDLVASIKEAGAIKRNEIKASRVTELELPDIKEVREKTGLTQAEFAARLHISARTLQNWEQGRRYPTGPAATLI
RILDAHPGLI
MDNNLFDDLVASIKEAGAIKRNEIKASRVTELELPDIKEVREKTGLTQAEFAARLHISARTLQNWEQGRRYPTGPAATLI
RILDAHPGLI
Download Length: 273 bp
>AT97585 NZ_CP027186:c2640-2368 [Acinetobacter baumannii]
ATGGATAACAACTTATTTGATGACCTGGTTGCTTCAATCAAAGAAGCTGGTGCCATCAAGCGTAATGAGATAAAGGCAAG
TCGAGTCACAGAGCTTGAATTACCGGATATTAAAGAAGTACGTGAGAAAACAGGCTTAACCCAGGCTGAATTTGCTGCAC
GTTTGCATATCAGTGCAAGAACCCTGCAAAACTGGGAACAAGGCCGTCGCTATCCGACTGGCCCAGCAGCAACTTTAATC
CGTATTCTTGATGCCCATCCAGGTCTGATTTAA
ATGGATAACAACTTATTTGATGACCTGGTTGCTTCAATCAAAGAAGCTGGTGCCATCAAGCGTAATGAGATAAAGGCAAG
TCGAGTCACAGAGCTTGAATTACCGGATATTAAAGAAGTACGTGAGAAAACAGGCTTAACCCAGGCTGAATTTGCTGCAC
GTTTGCATATCAGTGCAAGAACCCTGCAAAACTGGGAACAAGGCCGTCGCTATCCGACTGGCCCAGCAGCAACTTTAATC
CGTATTCTTGATGCCCATCCAGGTCTGATTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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