Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/YoeB-YefM |
Location | 615301..615803 | Replicon | chromosome |
Accession | NZ_CP026983 | ||
Organism | Pectobacterium parmentieri strain IFB5604 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | A0A8B3FFY4 |
Locus tag | C5E23_RS02975 | Protein ID | WP_025919527.1 |
Coordinates | 615301..615555 (-) | Length | 85 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | A0A8B3FIJ8 |
Locus tag | C5E23_RS02980 | Protein ID | WP_033070807.1 |
Coordinates | 615552..615803 (-) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C5E23_RS02955 | 610407..611669 | - | 1263 | WP_012822274.1 | L-rhamnose isomerase | - |
C5E23_RS02960 | 611666..613156 | - | 1491 | WP_012822275.1 | rhamnulokinase | - |
C5E23_RS02965 | 613525..614364 | + | 840 | WP_005971146.1 | HTH-type transcriptional activator RhaS | - |
C5E23_RS02970 | 614389..615243 | + | 855 | WP_012822276.1 | helix-turn-helix domain-containing protein | - |
C5E23_RS02975 | 615301..615555 | - | 255 | WP_025919527.1 | Txe/YoeB family addiction module toxin | Toxin |
C5E23_RS02980 | 615552..615803 | - | 252 | WP_033070807.1 | YoeB-YefM toxin-antitoxin system antitoxin YefM | Antitoxin |
C5E23_RS02985 | 615878..617566 | - | 1689 | WP_025919529.1 | ABC transporter ATP-binding protein | - |
C5E23_RS02990 | 617563..618429 | - | 867 | WP_012822280.1 | ABC transporter permease | - |
C5E23_RS02995 | 618422..619381 | - | 960 | WP_012822281.1 | ABC transporter permease | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | - | mgtB / hcp | 531934..674704 | 142770 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 10135.66 Da Isoelectric Point: 8.0367
>T96973 WP_025919527.1 NZ_CP026983:c615555-615301 [Pectobacterium parmentieri]
VKPIWSEAAWEDYLYWQDIDNRIVKKINELIKEIRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITDDAMMIAAC
RYHY
VKPIWSEAAWEDYLYWQDIDNRIVKKINELIKEIRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITDDAMMIAAC
RYHY
Download Length: 255 bp
>T96973 NZ_CP026983:c615555-615301 [Pectobacterium parmentieri]
GTGAAGCCAATCTGGTCAGAAGCAGCATGGGAAGACTACCTGTACTGGCAGGATATCGATAATCGGATAGTCAAAAAAAT
CAATGAATTAATAAAAGAAATTCGCAGAACGCCTTTTGAGGGAAAAGGAAAACCAGAGCCGCTTAAACATAATCTTGCTG
GCTTCTGGTCACGCCGTATCACCGAAGAACATCGTCTGGTCTATGCCATCACCGATGACGCCATGATGATCGCTGCCTGC
CGCTACCACTATTAA
GTGAAGCCAATCTGGTCAGAAGCAGCATGGGAAGACTACCTGTACTGGCAGGATATCGATAATCGGATAGTCAAAAAAAT
CAATGAATTAATAAAAGAAATTCGCAGAACGCCTTTTGAGGGAAAAGGAAAACCAGAGCCGCTTAAACATAATCTTGCTG
GCTTCTGGTCACGCCGTATCACCGAAGAACATCGTCTGGTCTATGCCATCACCGATGACGCCATGATGATCGCTGCCTGC
CGCTACCACTATTAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9351.64 Da Isoelectric Point: 4.6119
>AT96973 WP_033070807.1 NZ_CP026983:c615803-615552 [Pectobacterium parmentieri]
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNAIESLKAGNGEERD
IIE
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNAIESLKAGNGEERD
IIE
Download Length: 252 bp
>AT96973 NZ_CP026983:c615803-615552 [Pectobacterium parmentieri]
ATGCGTACAATTAGCTACAGCGAAGCCCGCCAAAACCTATCAGCAACCATGATGAAAACGGTCGAAGACCGTGCTCCCAT
TCTTATCACCCGACAGAATGGCGAAGCCTGTGTGCTGATGTCTCTGGAAGAGTATAACTCTCTAGAAGAAACCGCGTATT
TACTGCGTTCTCCCGCCAATGCCAAAAGACTGATGAATGCAATCGAGAGCCTTAAGGCTGGCAATGGCGAAGAAAGAGAT
ATCATTGAGTGA
ATGCGTACAATTAGCTACAGCGAAGCCCGCCAAAACCTATCAGCAACCATGATGAAAACGGTCGAAGACCGTGCTCCCAT
TCTTATCACCCGACAGAATGGCGAAGCCTGTGTGCTGATGTCTCTGGAAGAGTATAACTCTCTAGAAGAAACCGCGTATT
TACTGCGTTCTCCCGCCAATGCCAAAAGACTGATGAATGCAATCGAGAGCCTTAAGGCTGGCAATGGCGAAGAAAGAGAT
ATCATTGAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A8B3FFY4 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A8B3FIJ8 |