Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
Location | 482164..482789 | Replicon | chromosome |
Accession | NZ_CP026983 | ||
Organism | Pectobacterium parmentieri strain IFB5604 |
Toxin (Protein)
Gene name | higB | Uniprot ID | A0A8B3FNM7 |
Locus tag | C5E23_RS02405 | Protein ID | WP_033070820.1 |
Coordinates | 482164..482469 (+) | Length | 102 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | C5E23_RS02410 | Protein ID | WP_103808699.1 |
Coordinates | 482466..482789 (+) | Length | 108 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C5E23_RS02380 | 477886..478533 | + | 648 | WP_012822190.1 | type I-E CRISPR-associated protein Cas6/Cse3/CasE | - |
C5E23_RS02385 | 478561..479478 | + | 918 | WP_012822191.1 | type I-E CRISPR-associated endonuclease Cas1 | - |
C5E23_RS02390 | 479479..479772 | + | 294 | WP_005973730.1 | type I-E CRISPR-associated endoribonuclease Cas2 | - |
C5E23_RS02395 | 481307..481678 | - | 372 | WP_103808702.1 | helix-turn-helix domain-containing protein | - |
C5E23_RS02400 | 481752..482012 | - | 261 | WP_012822193.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
C5E23_RS02405 | 482164..482469 | + | 306 | WP_033070820.1 | type II toxin-antitoxin system HigB family toxin | Toxin |
C5E23_RS02410 | 482466..482789 | + | 324 | WP_103808699.1 | helix-turn-helix domain-containing protein | Antitoxin |
C5E23_RS02415 | 483952..484410 | + | 459 | WP_012822197.1 | hypothetical protein | - |
C5E23_RS02420 | 484491..485843 | - | 1353 | WP_103808643.1 | aspartate aminotransferase family protein | - |
C5E23_RS02425 | 485874..487145 | - | 1272 | WP_103808673.1 | MFS transporter | - |
C5E23_RS02430 | 487300..487746 | + | 447 | WP_012822200.1 | helix-turn-helix transcriptional regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 102 a.a. Molecular weight: 12010.78 Da Isoelectric Point: 10.0386
>T96970 WP_033070820.1 NZ_CP026983:482164-482469 [Pectobacterium parmentieri]
VFSRAPFDTAIAQFPNQAAALADLYRTIKREIYATPDDMKKRFPSLDRMKYREKWWVIDIGGGHLRVMFFADFERGKIFI
KHITSHAEYGSLTEYYRRNKE
VFSRAPFDTAIAQFPNQAAALADLYRTIKREIYATPDDMKKRFPSLDRMKYREKWWVIDIGGGHLRVMFFADFERGKIFI
KHITSHAEYGSLTEYYRRNKE
Download Length: 306 bp
>T96970 NZ_CP026983:482164-482469 [Pectobacterium parmentieri]
GTGTTCTCCCGTGCACCTTTTGACACTGCAATCGCCCAATTCCCGAATCAGGCGGCAGCACTGGCTGACCTATACCGGAC
GATAAAGCGTGAAATATATGCAACGCCGGACGATATGAAAAAACGTTTCCCCAGCTTAGACAGGATGAAGTACAGGGAAA
AGTGGTGGGTTATTGATATTGGTGGTGGGCATCTTCGGGTGATGTTTTTCGCTGATTTTGAGCGAGGGAAAATTTTTATC
AAACACATCACATCCCATGCAGAGTACGGCAGTCTGACAGAATATTACCGGAGGAATAAAGAATGA
GTGTTCTCCCGTGCACCTTTTGACACTGCAATCGCCCAATTCCCGAATCAGGCGGCAGCACTGGCTGACCTATACCGGAC
GATAAAGCGTGAAATATATGCAACGCCGGACGATATGAAAAAACGTTTCCCCAGCTTAGACAGGATGAAGTACAGGGAAA
AGTGGTGGGTTATTGATATTGGTGGTGGGCATCTTCGGGTGATGTTTTTCGCTGATTTTGAGCGAGGGAAAATTTTTATC
AAACACATCACATCCCATGCAGAGTACGGCAGTCTGACAGAATATTACCGGAGGAATAAAGAATGA
Antitoxin
Download Length: 108 a.a. Molecular weight: 11655.44 Da Isoelectric Point: 5.0877
>AT96970 WP_103808699.1 NZ_CP026983:482466-482789 [Pectobacterium parmentieri]
MMYADAIKAANNLTSIVPLLGGSTSCKDYEDAPEFVAFNERIKALPAGIALLRILMDQHGLTQSDFEAEIGKKSLVSRIL
NGERTLTVDHMSALAKRFDIPVSAFVD
MMYADAIKAANNLTSIVPLLGGSTSCKDYEDAPEFVAFNERIKALPAGIALLRILMDQHGLTQSDFEAEIGKKSLVSRIL
NGERTLTVDHMSALAKRFDIPVSAFVD
Download Length: 324 bp
>AT96970 NZ_CP026983:482466-482789 [Pectobacterium parmentieri]
ATGATGTACGCAGACGCAATCAAGGCCGCTAACAATCTGACGAGTATCGTACCGCTCCTCGGAGGTAGCACCTCTTGTAA
AGATTATGAGGATGCGCCAGAGTTTGTAGCTTTCAACGAGCGTATTAAAGCGCTCCCTGCTGGTATCGCTTTGCTGCGCA
TACTTATGGATCAGCATGGGCTAACGCAAAGTGACTTTGAAGCTGAGATCGGTAAAAAATCTCTGGTATCCCGAATTCTA
AATGGTGAGCGTACACTAACGGTTGATCACATGAGCGCACTTGCTAAACGATTTGATATTCCCGTGAGTGCTTTTGTTGA
TTAG
ATGATGTACGCAGACGCAATCAAGGCCGCTAACAATCTGACGAGTATCGTACCGCTCCTCGGAGGTAGCACCTCTTGTAA
AGATTATGAGGATGCGCCAGAGTTTGTAGCTTTCAACGAGCGTATTAAAGCGCTCCCTGCTGGTATCGCTTTGCTGCGCA
TACTTATGGATCAGCATGGGCTAACGCAAAGTGACTTTGAAGCTGAGATCGGTAAAAAATCTCTGGTATCCCGAATTCTA
AATGGTGAGCGTACACTAACGGTTGATCACATGAGCGCACTTGCTAAACGATTTGATATTCCCGTGAGTGCTTTTGTTGA
TTAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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