Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 570924..571426 Replicon chromosome
Accession NZ_CP026979
Organism Pectobacterium parmentieri strain IFB5432

Toxin (Protein)


Gene name yoeB Uniprot ID A0A8B3FFY4
Locus tag C5E19_RS02710 Protein ID WP_025919527.1
Coordinates 570924..571178 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A8B3FIJ8
Locus tag C5E19_RS02715 Protein ID WP_033070807.1
Coordinates 571175..571426 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C5E19_RS02690 566034..567235 - 1202 Protein_513 L-rhamnose isomerase -
C5E19_RS02695 567226..568779 - 1554 WP_162940849.1 rhamnulokinase -
C5E19_RS02700 569148..569987 + 840 WP_005971146.1 HTH-type transcriptional activator RhaS -
C5E19_RS02705 570012..570866 + 855 WP_121264106.1 helix-turn-helix domain-containing protein -
C5E19_RS02710 570924..571178 - 255 WP_025919527.1 Txe/YoeB family addiction module toxin Toxin
C5E19_RS02715 571175..571426 - 252 WP_033070807.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
C5E19_RS02720 571501..573189 - 1689 WP_014698652.1 ABC transporter ATP-binding protein -
C5E19_RS02725 573186..574052 - 867 WP_012822280.1 ABC transporter permease -
C5E19_RS02730 574045..575004 - 960 WP_012822281.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10135.66 Da        Isoelectric Point: 8.0367

>T96938 WP_025919527.1 NZ_CP026979:c571178-570924 [Pectobacterium parmentieri]
VKPIWSEAAWEDYLYWQDIDNRIVKKINELIKEIRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITDDAMMIAAC
RYHY

Download         Length: 255 bp

>T96938 NZ_CP026979:c571178-570924 [Pectobacterium parmentieri]
GTGAAGCCAATCTGGTCAGAAGCAGCATGGGAAGACTACCTGTACTGGCAGGATATCGATAATCGGATAGTCAAAAAAAT
CAATGAATTAATAAAAGAAATTCGCAGAACGCCTTTTGAGGGAAAAGGAAAACCAGAGCCGCTTAAACATAATCTTGCTG
GCTTCTGGTCACGCCGTATCACCGAAGAACATCGTCTGGTCTATGCCATCACCGATGACGCCATGATGATCGCTGCCTGC
CGCTACCACTATTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9351.64 Da        Isoelectric Point: 4.6119

>AT96938 WP_033070807.1 NZ_CP026979:c571426-571175 [Pectobacterium parmentieri]
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNAIESLKAGNGEERD
IIE

Download         Length: 252 bp

>AT96938 NZ_CP026979:c571426-571175 [Pectobacterium parmentieri]
ATGCGTACAATTAGCTACAGCGAAGCCCGCCAAAACCTATCAGCAACCATGATGAAAACGGTCGAAGACCGTGCTCCCAT
TCTTATCACCCGACAGAATGGCGAAGCCTGTGTGCTGATGTCTCTGGAAGAGTATAACTCTCTAGAAGAAACCGCGTATT
TACTGCGTTCTCCCGCCAATGCCAAAAGACTGATGAATGCAATCGAGAGCCTTAAGGCTGGCAATGGCGAAGAAAGAGAT
ATCATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A8B3FFY4

Antitoxin

Source ID Structure
AlphaFold DB A0A8B3FIJ8

References