96910

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2364655..2364839 Replicon chromosome
Accession NZ_CP026968
Organism Staphylococcus aureus strain FDAARGOS_1

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag RK60_RS12575 Protein ID WP_000482652.1
Coordinates 2364732..2364839 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2364655..2364715 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK60_RS12550 2360110..2360277 - 168 Protein_2323 hypothetical protein -
RK60_RS12560 2360508..2362241 - 1734 WP_000486487.1 ABC transporter ATP-binding protein/permease -
RK60_RS12565 2362266..2364029 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
- 2364655..2364715 + 61 - - Antitoxin
RK60_RS12575 2364732..2364839 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
RK60_RS12580 2364973..2365359 - 387 WP_000779360.1 flippase GtxA -
RK60_RS12585 2365627..2366769 + 1143 WP_001176863.1 glycerate kinase -
RK60_RS12590 2366829..2367488 + 660 WP_000831298.1 membrane protein -
RK60_RS12595 2367670..2368881 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
RK60_RS12600 2369004..2369477 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T96910 WP_000482652.1 NZ_CP026968:c2364839-2364732 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T96910 NZ_CP026968:c2364839-2364732 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT96910 NZ_CP026968:2364655-2364715 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References