Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2079058..2079274 Replicon chromosome
Accession NZ_CP026968
Organism Staphylococcus aureus strain FDAARGOS_1

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag RK60_RS11010 Protein ID WP_001802298.1
Coordinates 2079170..2079274 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2079058..2079113 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK60_RS10990 2075264..2075929 - 666 WP_001024095.1 SDR family oxidoreductase -
RK60_RS10995 2076081..2076401 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
RK60_RS11000 2076403..2077380 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
RK60_RS11005 2077646..2078737 + 1092 WP_000495669.1 hypothetical protein -
- 2079058..2079113 + 56 - - Antitoxin
RK60_RS11010 2079170..2079274 - 105 WP_001802298.1 hypothetical protein Toxin
RK60_RS11020 2079954..2080112 + 159 WP_001792784.1 hypothetical protein -
RK60_RS11030 2080770..2081627 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
RK60_RS11035 2081695..2082477 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T96907 WP_001802298.1 NZ_CP026968:c2079274-2079170 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T96907 NZ_CP026968:c2079274-2079170 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT96907 NZ_CP026968:2079058-2079113 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References