Detailed information of TA system TA096898

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1744060..1744240
• Replicon: chromosome
• Accession: NZ_CP026968
• Organism: Staphylococcus aureus strain FDAARGOS_1

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: RK60_RS14970
• Protein ID: WP_001801861.1
• Coordinates: 1744060..1744155 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1744183..1744240 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RK60_RS08895	1739223..1739873	+	651	WP_001795210.1	excalibur calcium-binding domain-containing protein	-
RK60_RS08900	1739954..1740949	+	996	WP_000070642.1	DUF4352 domain-containing protein	-
RK60_RS08905	1741024..1741650	+	627	WP_016170738.1	hypothetical protein	-
RK60_RS08910	1741691..1742032	+	342	WP_000627540.1	DUF3969 family protein	-
RK60_RS08915	1742133..1742705	+	573	WP_000414216.1	hypothetical protein	-
RK60_RS08920	1742903..1743915	-	1013	Protein_1680	IS3 family transposase	-
RK60_RS14970	1744060..1744155	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1744183..1744240	-	58	-	-	Antitoxin
RK60_RS08925	1744278..1744379	+	102	WP_001792025.1	hypothetical protein	-
RK60_RS08930	1744357..1744518	-	162	Protein_1683	transposase	-
RK60_RS08935	1744509..1745003	-	495	Protein_1684	transposase	-
RK60_RS08940	1745455..1746684	-	1230	WP_000072627.1	restriction endonuclease subunit S	-
RK60_RS08945	1746677..1748233	-	1557	WP_000028669.1	type I restriction-modification system subunit M	-
RK60_RS08950	1748397..1748531	-	135	WP_001791797.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA / selk	1720436..1771072	50636

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T96898 WP_001801861.1 NZ_CP026968:1744060-1744155 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T96898 NZ_CP026968:1744060-1744155 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT96898 NZ_CP026968:c1744240-1744183 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin