Detailed information of TA system TA096890

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1689354..1689536
• Replicon: chromosome
• Accession: NZ_CP026964
• Organism: Staphylococcus aureus strain FDAARGOS_2

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: RK61_RS14600
• Protein ID: WP_001801861.1
• Coordinates: 1689441..1689536 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1689354..1689413 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RK61_RS08850	1688492..1688869	+	378	Protein_1604	DUF1433 domain-containing protein	-
RK61_RS08855	1689063..1689239	+	177	Protein_1605	transposase	-
RK61_RS08860	1689217..1689318	-	102	WP_001791893.1	hypothetical protein	-
-	1689354..1689413	+	60	-	-	Antitoxin
RK61_RS14600	1689441..1689536	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
RK61_RS08870	1689739..1689882	+	144	WP_001549059.1	transposase	-
RK61_RS08880	1690486..1690869	+	384	WP_000070814.1	hypothetical protein	-
RK61_RS08885	1690880..1691056	+	177	WP_000375477.1	hypothetical protein	-
RK61_RS08895	1691430..1691987	+	558	Protein_1611	ImmA/IrrE family metallo-endopeptidase	-
RK61_RS08900	1692185..1692757	-	573	WP_000414202.1	hypothetical protein	-
RK61_RS08905	1692858..1693199	-	342	WP_000627541.1	DUF3969 family protein	-
RK61_RS08910	1693240..1693866	-	627	WP_000669017.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1672579..1696424	23845

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T96890 WP_001801861.1 NZ_CP026964:c1689536-1689441 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T96890 NZ_CP026964:c1689536-1689441 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT96890 NZ_CP026964:1689354-1689413 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin