Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 272503..272766 Replicon chromosome
Accession NZ_CP026961
Organism Staphylococcus aureus strain FDAARGOS_10

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag RK68_RS01755 Protein ID WP_001802298.1
Coordinates 272662..272766 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 272503..272667 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK68_RS01735 268743..269408 - 666 WP_001024094.1 SDR family oxidoreductase -
RK68_RS01740 269560..269880 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
RK68_RS01745 269882..270862 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
RK68_RS01750 271128..272219 + 1092 WP_000495671.1 lytic regulatory protein -
- 272503..272667 + 165 - - Antitoxin
RK68_RS01755 272662..272766 - 105 WP_001802298.1 hypothetical protein Toxin
RK68_RS15280 272927..273410 - 484 Protein_330 recombinase family protein -
RK68_RS01765 273453..274589 - 1137 WP_000115562.1 SAP domain-containing protein -
RK68_RS01770 274878..274970 + 93 WP_001790138.1 hypothetical protein -
RK68_RS01775 275675..276532 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
RK68_RS01780 276600..277382 - 783 WP_000908177.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T96852 WP_001802298.1 NZ_CP026961:c272766-272662 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T96852 NZ_CP026961:c272766-272662 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT96852 NZ_CP026961:272503-272667 [Staphylococcus aureus]
GTAGCAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References