96842

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1843320..1843504 Replicon chromosome
Accession NZ_CP026960
Organism Staphylococcus aureus strain FDAARGOS_15

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag RK73_RS09865 Protein ID WP_000482650.1
Coordinates 1843397..1843504 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1843320..1843380 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK73_RS09840 1838850..1839017 - 168 WP_001790576.1 hypothetical protein -
RK73_RS09850 1839248..1840981 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
RK73_RS09855 1841006..1842769 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 1843320..1843380 + 61 - - Antitoxin
RK73_RS09865 1843397..1843504 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
RK73_RS09870 1843638..1844024 - 387 WP_000779358.1 flippase GtxA -
RK73_RS09875 1844292..1845434 + 1143 WP_001176863.1 glycerate kinase -
RK73_RS09880 1845494..1846153 + 660 WP_000831298.1 membrane protein -
RK73_RS09885 1846335..1847546 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
RK73_RS09890 1847669..1848142 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T96842 WP_000482650.1 NZ_CP026960:c1843504-1843397 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T96842 NZ_CP026960:c1843504-1843397 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT96842 NZ_CP026960:1843320-1843380 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References