Detailed information of TA system TA096835

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1217937..1218119
• Replicon: chromosome
• Accession: NZ_CP026960
• Organism: Staphylococcus aureus strain FDAARGOS_15

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: RK73_RS14695
• Protein ID: WP_001801861.1
• Coordinates: 1217937..1218032 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1218060..1218119 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RK73_RS06165	1213597..1214223	+	627	WP_000669046.1	hypothetical protein	-
RK73_RS06170	1214264..1214608	+	345	WP_000627551.1	DUF3969 family protein	-
RK73_RS06175	1214706..1215257	+	552	WP_000414205.1	hypothetical protein	-
RK73_RS06180	1215475..1216116	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
RK73_RS06185	1216230..1216415	-	186	WP_000809857.1	hypothetical protein	-
RK73_RS06190	1216417..1216593	-	177	WP_000375476.1	hypothetical protein	-
RK73_RS06195	1216604..1216987	-	384	WP_000070812.1	hypothetical protein	-
RK73_RS06205	1217591..1217734	-	144	WP_001549059.1	transposase	-
RK73_RS14695	1217937..1218032	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1218060..1218119	-	60	-	-	Antitoxin
RK73_RS06215	1218155..1218256	+	102	WP_001791893.1	hypothetical protein	-
RK73_RS06220	1218234..1218410	-	177	Protein_1192	transposase	-
RK73_RS06225	1218604..1218981	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1211037..1236638	25601

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T96835 WP_001801861.1 NZ_CP026960:1217937-1218032 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T96835 NZ_CP026960:1217937-1218032 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT96835 NZ_CP026960:c1218119-1218060 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin