Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1806753..1807031 Replicon chromosome
Accession NZ_CP026958
Organism Staphylococcus aureus strain FDAARGOS_40

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag RK98_RS09475 Protein ID WP_001802298.1
Coordinates 1806753..1806857 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 1806853..1807031 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK98_RS09450 1803550..1804332 + 783 WP_000908182.1 ABC transporter ATP-binding protein -
RK98_RS09455 1804400..1805257 + 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
RK98_RS09465 1805915..1806073 - 159 WP_001792784.1 hypothetical protein -
RK98_RS15245 1806066..1806236 - 171 WP_001792292.1 transposase -
RK98_RS09475 1806753..1806857 + 105 WP_001802298.1 hypothetical protein Toxin
- 1806853..1807031 - 179 - - Antitoxin
RK98_RS09480 1807290..1808381 - 1092 WP_000495669.1 hypothetical protein -
RK98_RS09485 1808647..1809624 - 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
RK98_RS09490 1809626..1809946 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
RK98_RS09495 1810098..1810763 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T96827 WP_001802298.1 NZ_CP026958:1806753-1806857 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T96827 NZ_CP026958:1806753-1806857 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 179 bp

>AT96827 NZ_CP026958:c1807031-1806853 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References