Detailed information of TA system TA096815

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 121940..122120
• Replicon: chromosome
• Accession: NZ_CP026958
• Organism: Staphylococcus aureus strain FDAARGOS_40

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: RK98_RS15130
• Protein ID: WP_001801861.1
• Coordinates: 121940..122035 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	122063..122120 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RK98_RS00540	117103..117753	+	651	WP_001795210.1	excalibur calcium-binding domain-containing protein	-
RK98_RS00545	117834..118829	+	996	WP_000070642.1	DUF4352 domain-containing protein	-
RK98_RS00550	118904..119530	+	627	WP_000669024.1	hypothetical protein	-
RK98_RS00555	119571..119912	+	342	WP_000627540.1	DUF3969 family protein	-
RK98_RS00560	120013..120585	+	573	WP_000414216.1	hypothetical protein	-
RK98_RS00565	120783..121795	-	1013	Protein_109	IS3 family transposase	-
RK98_RS15130	121940..122035	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	122063..122120	-	58	-	-	Antitoxin
RK98_RS00570	122158..122259	+	102	WP_001792025.1	hypothetical protein	-
RK98_RS00575	122237..122398	-	162	Protein_112	transposase	-
RK98_RS00580	122389..122883	-	495	Protein_113	transposase	-
RK98_RS00585	123335..124564	-	1230	WP_000072626.1	restriction endonuclease subunit S	-
RK98_RS00590	124557..126113	-	1557	WP_000028669.1	type I restriction-modification system subunit M	-
RK98_RS00595	126277..126411	-	135	WP_001791797.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA / selk	116345..168353	52008

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T96815 WP_001801861.1 NZ_CP026958:121940-122035 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T96815 NZ_CP026958:121940-122035 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT96815 NZ_CP026958:c122120-122063 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin