96810

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2728381..2728659 Replicon chromosome
Accession NZ_CP026957
Organism Staphylococcus aureus strain FDAARGOS_43

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag RL01_RS14115 Protein ID WP_001802298.1
Coordinates 2728381..2728485 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2728481..2728659 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RL01_RS14090 2725177..2725959 + 783 WP_000908178.1 ABC transporter ATP-binding protein -
RL01_RS14095 2726027..2726884 + 858 WP_000370917.1 Cof-type HAD-IIB family hydrolase -
RL01_RS14105 2727543..2727701 - 159 WP_001792784.1 hypothetical protein -
RL01_RS14115 2728381..2728485 + 105 WP_001802298.1 hypothetical protein Toxin
- 2728481..2728659 - 179 - - Antitoxin
RL01_RS14120 2728918..2730009 - 1092 WP_000495683.1 hypothetical protein -
RL01_RS14125 2730275..2731255 - 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
RL01_RS14130 2731257..2731577 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
RL01_RS14135 2731729..2732394 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T96810 WP_001802298.1 NZ_CP026957:2728381-2728485 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T96810 NZ_CP026957:2728381-2728485 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 179 bp

>AT96810 NZ_CP026957:c2728659-2728481 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References