96806

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2450015..2450199 Replicon chromosome
Accession NZ_CP026957
Organism Staphylococcus aureus strain FDAARGOS_43

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag RL01_RS12595 Protein ID WP_000482647.1
Coordinates 2450015..2450122 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2450139..2450199 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RL01_RS12570 2445387..2445860 + 474 WP_000456497.1 GyrI-like domain-containing protein -
RL01_RS12575 2445983..2447194 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
RL01_RS12580 2447376..2448035 - 660 WP_000831301.1 membrane protein -
RL01_RS12585 2448095..2449237 - 1143 WP_001176871.1 glycerate kinase -
RL01_RS12590 2449495..2449881 + 387 WP_000779360.1 flippase GtxA -
RL01_RS12595 2450015..2450122 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2450139..2450199 - 61 - - Antitoxin
RL01_RS12605 2450806..2452569 + 1764 WP_001064815.1 ABC transporter ATP-binding protein/permease -
RL01_RS12610 2452594..2454327 + 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
RL01_RS12620 2454558..2454725 + 168 WP_001793334.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T96806 WP_000482647.1 NZ_CP026957:2450015-2450122 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T96806 NZ_CP026957:2450015-2450122 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT96806 NZ_CP026957:c2450199-2450139 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References