Detailed information of TA system TA096797

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 240131..240313
• Replicon: chromosome
• Accession: NZ_CP026957
• Organism: Staphylococcus aureus strain FDAARGOS_43

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: RL01_RS14625
• Protein ID: WP_001801861.1
• Coordinates: 240218..240313 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	240131..240190 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RL01_RS01520	239269..239646	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
RL01_RS01525	239840..240016	+	177	Protein_247	transposase	-
RL01_RS01530	239994..240095	-	102	WP_001791893.1	hypothetical protein	-
-	240131..240190	+	60	-	-	Antitoxin
RL01_RS14625	240218..240313	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
RL01_RS01540	240516..240659	+	144	WP_001549059.1	transposase	-
RL01_RS01550	241263..241646	+	384	WP_000070811.1	hypothetical protein	-
RL01_RS01555	241657..241833	+	177	WP_000375477.1	hypothetical protein	-
RL01_RS01565	242207..242764	+	558	Protein_253	ImmA/IrrE family metallo-endopeptidase	-
RL01_RS01570	242962..243534	-	573	WP_000414202.1	hypothetical protein	-
RL01_RS01575	243635..243976	-	342	WP_000627541.1	DUF3969 family protein	-
RL01_RS01580	244017..244643	-	627	WP_000669017.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	223355..247201	23846

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T96797 WP_001801861.1 NZ_CP026957:c240313-240218 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T96797 NZ_CP026957:c240313-240218 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT96797 NZ_CP026957:240131-240190 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin