Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3956246..3956468 Replicon chromosome
Accession NZ_CP026853
Organism Escherichia coli strain MS7163

Toxin (Protein)


Gene name ldrD Uniprot ID S1NWX0
Locus tag MS7163_RS20795 Protein ID WP_001295224.1
Coordinates 3956246..3956353 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3956410..3956468 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MS7163_RS20770 3951500..3952252 - 753 WP_000279545.1 cellulose biosynthesis protein BcsQ -
MS7163_RS20775 3952264..3952452 - 189 WP_001063314.1 YhjR family protein -
MS7163_RS20780 3952725..3954296 + 1572 WP_001204957.1 cellulose biosynthesis protein BcsE -
MS7163_RS20785 3954293..3954484 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
MS7163_RS20790 3954481..3956160 + 1680 WP_000191616.1 cellulose biosynthesis protein BcsG -
MS7163_RS20795 3956246..3956353 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- 3956410..3956468 + 59 - - Antitoxin
MS7163_RS28260 3956729..3956836 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
MS7163_RS20815 3957211..3957318 - 108 WP_000170745.1 type I toxin-antitoxin system toxin Ldr family protein -
MS7163_RS20825 3957794..3959065 + 1272 WP_001332306.1 amino acid permease -
MS7163_RS20830 3959095..3960099 - 1005 WP_000103579.1 dipeptide ABC transporter ATP-binding subunit DppF -
MS7163_RS20835 3960096..3961079 - 984 WP_001196477.1 dipeptide ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3882.70 Da        Isoelectric Point: 9.0157

>T96498 WP_001295224.1 NZ_CP026853:c3956353-3956246 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T96498 NZ_CP026853:c3956353-3956246 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 59 bp

>AT96498 NZ_CP026853:3956410-3956468 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TSJ7

Antitoxin

Download structure file

References