Detailed information of TA system TA096447

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 2973484..2973704
• Replicon: chromosome
• Accession: NZ_CP026846
• Organism: Shigella boydii strain 59-2708

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: -
• Locus tag: C1P57_RS15055
• Protein ID: WP_078166279.1
• Coordinates: 2973597..2973704 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	2973484..2973550 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C1P57_RS15030	2968762..2970156	-	1395	WP_024258159.1	inverse autotransporter invasin YchO	-
C1P57_RS15035	2970342..2970695	+	354	WP_001169669.1	DsrE/F sulfur relay family protein YchN	-
C1P57_RS15040	2970739..2971434	-	696	WP_078166256.1	glutathione-specific gamma-glutamylcyclotransferase	-
C1P57_RS15045	2971592..2971822	-	231	WP_001146444.1	putative cation transport regulator ChaB	-
C1P57_RS15050	2972092..2973192	+	1101	WP_001295620.1	sodium-potassium/proton antiporter ChaA	-
-	2973484..2973550	-	67	-	-	Antitoxin
C1P57_RS15055	2973597..2973704	+	108	WP_078166279.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
C1P57_RS15060	2973853..2974707	-	855	WP_000811073.1	3-deoxy-8-phosphooctulonate synthase	-
C1P57_RS15065	2974743..2975552	-	810	WP_078166257.1	invasion regulator SirB1	-
C1P57_RS15070	2975556..2975948	-	393	WP_000200382.1	invasion regulator SirB2	-
C1P57_RS15075	2975945..2976777	-	833	Protein_2924	peptide chain release factor N(5)-glutamine methyltransferase	-
C1P57_RS15080	2976777..2977859	-	1083	WP_000804726.1	peptide chain release factor 1	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.84 Da
• Isoelectric Point: 12.5163

>T96447 WP_078166279.1 NZ_CP026846:2973597-2973704 [Shigella boydii]
MTLAQFAMIFWHNLAAPILAGIITAAIVSWWRNRK

Nucleotide

• Length: 108 bp

>T96447 NZ_CP026846:2973597-2973704 [Shigella boydii]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCATAACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin

Nucleotide

• Length: 67 bp

>AT96447 NZ_CP026846:c2973550-2973484 [Shigella boydii]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTATACCTCTCAACGTGCGGGGGTTTTCT

Structures

Antitoxin