Detailed information of TA system TA096427

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): symER/SymE(toxin)
• Location: 868476..868888
• Replicon: chromosome
• Accession: NZ_CP026846
• Organism: Shigella boydii strain 59-2708

Toxin (Protein)

• Gene name: symE
• Uniprot ID: -
• Locus tag: C1P57_RS04235
• Protein ID: WP_000132622.1
• Coordinates: 868476..868817 (-)
• Length: 114 a.a.

Antitoxin (RNA)

Gene name	symR
Locus tag	-
Coordinates	868812..868888 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C1P57_RS04215 (864487)	864487..865899	-	1413	WP_078166383.1	PLP-dependent aminotransferase family protein	-
C1P57_RS04220 (866076)	866076..866240	+	165	WP_000394268.1	DUF1127 domain-containing protein	-
C1P57_RS04225 (866337)	866337..867218	+	882	WP_134795560.1	DUF262 domain-containing protein	-
C1P57_RS04230 (867266)	867266..868429	+	1164	WP_134795561.1	DUF1524 domain-containing protein	-
C1P57_RS04235 (868476)	868476..868817	-	342	WP_000132622.1	endoribonuclease SymE	Toxin
- (868812)	868812..868888	+	77	NuclAT_18	-	Antitoxin
- (868812)	868812..868888	+	77	NuclAT_18	-	Antitoxin
- (868812)	868812..868888	+	77	NuclAT_18	-	Antitoxin
- (868812)	868812..868888	+	77	NuclAT_18	-	Antitoxin
- (868812)	868812..868888	+	77	NuclAT_19	-	Antitoxin
- (868812)	868812..868888	+	77	NuclAT_19	-	Antitoxin
- (868812)	868812..868888	+	77	NuclAT_19	-	Antitoxin
- (868812)	868812..868888	+	77	NuclAT_19	-	Antitoxin
C1P57_RS04240 (869038)	869038..870774	-	1737	WP_134795562.1	restriction endonuclease subunit S	-
C1P57_RS04245 (870774)	870774..872242	-	1469	Protein_819	N-6 DNA methylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	866337..876661	10324

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (20-71)

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 12340.11 Da
• Isoelectric Point: 7.8227

>T96427 WP_000132622.1 NZ_CP026846:c868817-868476 [Shigella boydii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQSPAPEESE
LMQSLRQVCKLSARKQRQVQEFIGVIAGKQKVA

Nucleotide

• Length: 342 bp

>T96427 NZ_CP026846:c868817-868476 [Shigella boydii]
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGCCGCTACCCGGATTACAGCCGTATTCCCGCCATCACTCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACGGCGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCTCAATCACCCGCCCCCGAAGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCACGTAAACAAAGGCAGGTGCAGGAGTTTATTGGGGTAATTGC
TGGTAAACAGAAAGTTGCCTGA

Antitoxin

Nucleotide

• Length: 77 bp

>AT96427 NZ_CP026846:868812-868888 [Shigella boydii]
AGTCATAACTGCTATTCTCCGATAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Structures

Antitoxin