Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 1101270..1101785 Replicon chromosome
Accession NZ_CP026734
Organism Brevibacterium linens strain ATCC 19391

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CXR29_RS04740 Protein ID WP_101555967.1
Coordinates 1101531..1101785 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag CXR29_RS04735 Protein ID WP_101555966.1
Coordinates 1101270..1101530 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CXR29_RS17255 1096992..1097702 - 711 WP_164742777.1 hypothetical protein -
CXR29_RS04725 1097949..1099334 - 1386 Protein_931 hypothetical protein -
CXR29_RS04730 1099412..1101160 + 1749 WP_127365267.1 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase -
CXR29_RS04735 1101270..1101530 + 261 WP_101555966.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CXR29_RS04740 1101531..1101785 + 255 WP_101555967.1 Txe/YoeB family addiction module toxin Toxin
CXR29_RS04745 1101897..1103261 - 1365 WP_127364039.1 isochorismate synthase -
CXR29_RS04750 1103344..1104072 + 729 WP_101555987.1 demethylmenaquinone methyltransferase -
CXR29_RS04755 1104075..1105376 + 1302 WP_127364040.1 geranylgeranyl reductase family protein -
CXR29_RS04760 1105471..1106481 + 1011 WP_127365268.1 polyprenyl synthetase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-65)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9909.35 Da        Isoelectric Point: 7.2139

>T95610 WP_101555967.1 NZ_CP026734:1101531-1101785 [Brevibacterium linens]
VRLVWDEAAWEDCKHWQTADRKILKRINTLIDACLREPFSGIGKPEQLKYGAQGSWSRRITDEHRLVYLVVDDDLVILQA
RYHC

Download         Length: 255 bp

>T95610 NZ_CP026734:1101531-1101785 [Brevibacterium linens]
GTGCGTCTGGTCTGGGACGAGGCGGCCTGGGAGGACTGCAAACACTGGCAGACTGCCGATCGGAAGATACTGAAGCGCAT
CAATACGCTCATCGACGCCTGCCTGCGTGAACCGTTCTCGGGGATCGGCAAGCCCGAACAGCTGAAGTACGGAGCCCAGG
GCTCGTGGTCGCGGCGCATCACCGATGAGCACCGACTGGTCTATCTCGTCGTCGACGACGACCTCGTGATTCTTCAGGCC
CGCTACCACTGCTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9760.82 Da        Isoelectric Point: 4.6812

>AT95610 WP_101555966.1 NZ_CP026734:1101270-1101530 [Brevibacterium linens]
MSISASEARKTLFPLIERVNEDRDAVEIVSRRGNAVLMSADDYAAWQETAYLFRSPANARRLLDAYDRARGGKVEFHDLD
RADEEA

Download         Length: 261 bp

>AT95610 NZ_CP026734:1101270-1101530 [Brevibacterium linens]
ATGTCCATCAGCGCAAGCGAGGCTCGCAAGACCTTGTTCCCGCTCATTGAGCGAGTGAATGAAGACCGTGATGCCGTCGA
GATCGTCTCTCGCAGGGGCAATGCTGTCCTGATGTCGGCTGACGATTACGCTGCATGGCAGGAGACTGCCTACCTGTTCC
GGTCGCCGGCCAACGCGCGCCGTCTGCTCGATGCCTATGACCGTGCCCGCGGCGGGAAGGTCGAGTTCCACGACCTTGAT
CGCGCGGATGAGGAAGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References