Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 487868..488568 Replicon chromosome
Accession NZ_CP026675
Organism Pseudomonas sp. SWI36

Toxin (Protein)


Gene name mqsR Uniprot ID A0A2L1I9F3
Locus tag C4Q27_RS02520 Protein ID WP_064493136.1
Coordinates 488272..488568 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A2L1I9E4
Locus tag C4Q27_RS02515 Protein ID WP_019437852.1
Coordinates 487868..488269 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4Q27_RS02495 482937..483758 - 822 WP_020193859.1 transporter substrate-binding domain-containing protein -
C4Q27_RS02500 483834..484775 - 942 WP_004573654.1 FAD-binding protein -
C4Q27_RS02505 484777..485526 - 750 WP_003254232.1 electron transfer flavoprotein subunit beta/FixA family protein -
C4Q27_RS02510 486062..487744 + 1683 WP_104886406.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
C4Q27_RS02515 487868..488269 - 402 WP_019437852.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
C4Q27_RS02520 488272..488568 - 297 WP_064493136.1 type II toxin-antitoxin system MqsR family toxin Toxin
C4Q27_RS02525 488663..489988 - 1326 WP_104886407.1 MFS transporter -
C4Q27_RS02530 490061..490540 - 480 WP_019437855.1 hypothetical protein -
C4Q27_RS02535 490709..491185 - 477 WP_064493134.1 sigma-70 family RNA polymerase sigma factor -
C4Q27_RS02540 491399..492577 + 1179 WP_064493133.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(6-97)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11196.05 Da        Isoelectric Point: 8.8385

>T95427 WP_064493136.1 NZ_CP026675:c488568-488272 [Pseudomonas sp. SWI36]
MEKRMPHCPLERVRALVGAGRISPTTASLRGAQALGMEYADMLEVITGLERRDFYKSMTSYADHRVWQDVYRPLTVKGYL
YLKLSVVDDALIVSFKEL

Download         Length: 297 bp

>T95427 NZ_CP026675:c488568-488272 [Pseudomonas sp. SWI36]
ATGGAAAAGAGAATGCCTCATTGCCCGCTGGAGCGGGTAAGAGCACTGGTGGGCGCTGGCCGCATCAGCCCTACAACCGC
TTCCTTACGAGGCGCTCAGGCCTTGGGAATGGAATATGCGGACATGCTGGAGGTCATCACCGGTCTGGAGCGCAGAGATT
TCTACAAAAGCATGACCAGTTATGCCGACCACCGCGTTTGGCAAGATGTCTATCGGCCGCTTACGGTAAAGGGATATCTG
TACCTGAAACTGTCAGTGGTAGATGACGCGCTCATCGTGTCTTTCAAGGAGTTGTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14818.86 Da        Isoelectric Point: 4.6580

>AT95427 WP_019437852.1 NZ_CP026675:c488269-487868 [Pseudomonas sp. SWI36]
MRCPICGGAELALDTQDMPYRYKGESTLIPDVTGDYCSVCGEAVLSHDEAMRVSDLMSAFNRQVNALDVDPDFIVSVRKK
FDLDQREAGEIFGGGVNAFSRYENGKTKPPVALIKLFKLLDRHPELFEEVRTA

Download         Length: 402 bp

>AT95427 NZ_CP026675:c488269-487868 [Pseudomonas sp. SWI36]
ATGAGATGCCCAATTTGCGGAGGTGCCGAGCTCGCGCTAGACACTCAGGACATGCCCTACCGGTATAAGGGGGAATCGAC
CCTGATACCTGATGTGACGGGCGATTACTGTTCTGTCTGTGGTGAGGCAGTGCTAAGTCATGACGAGGCTATGCGAGTCA
GCGATCTGATGTCTGCCTTCAATCGCCAAGTCAATGCTCTAGACGTTGATCCCGATTTCATCGTTTCCGTACGCAAGAAA
TTTGATCTGGATCAGCGGGAGGCTGGGGAAATATTCGGTGGAGGAGTCAATGCTTTTTCGCGTTATGAGAATGGCAAAAC
CAAACCGCCGGTGGCGCTGATCAAATTGTTCAAGTTGCTCGACCGTCACCCGGAGCTCTTTGAGGAAGTCAGGACTGCGT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2L1I9F3

Antitoxin

Source ID Structure
AlphaFold DB A0A2L1I9E4

References