Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mqsRA (relBE)/MqsR-MqsA |
Location | 487868..488568 | Replicon | chromosome |
Accession | NZ_CP026675 | ||
Organism | Pseudomonas sp. SWI36 |
Toxin (Protein)
Gene name | mqsR | Uniprot ID | A0A2L1I9F3 |
Locus tag | C4Q27_RS02520 | Protein ID | WP_064493136.1 |
Coordinates | 488272..488568 (-) | Length | 99 a.a. |
Antitoxin (Protein)
Gene name | mqsA | Uniprot ID | A0A2L1I9E4 |
Locus tag | C4Q27_RS02515 | Protein ID | WP_019437852.1 |
Coordinates | 487868..488269 (-) | Length | 134 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C4Q27_RS02495 | 482937..483758 | - | 822 | WP_020193859.1 | transporter substrate-binding domain-containing protein | - |
C4Q27_RS02500 | 483834..484775 | - | 942 | WP_004573654.1 | FAD-binding protein | - |
C4Q27_RS02505 | 484777..485526 | - | 750 | WP_003254232.1 | electron transfer flavoprotein subunit beta/FixA family protein | - |
C4Q27_RS02510 | 486062..487744 | + | 1683 | WP_104886406.1 | electron transfer flavoprotein-ubiquinone oxidoreductase | - |
C4Q27_RS02515 | 487868..488269 | - | 402 | WP_019437852.1 | type II toxin-antitoxin system MqsA family antitoxin | Antitoxin |
C4Q27_RS02520 | 488272..488568 | - | 297 | WP_064493136.1 | type II toxin-antitoxin system MqsR family toxin | Toxin |
C4Q27_RS02525 | 488663..489988 | - | 1326 | WP_104886407.1 | MFS transporter | - |
C4Q27_RS02530 | 490061..490540 | - | 480 | WP_019437855.1 | hypothetical protein | - |
C4Q27_RS02535 | 490709..491185 | - | 477 | WP_064493134.1 | sigma-70 family RNA polymerase sigma factor | - |
C4Q27_RS02540 | 491399..492577 | + | 1179 | WP_064493133.1 | efflux RND transporter periplasmic adaptor subunit | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11196.05 Da Isoelectric Point: 8.8385
>T95427 WP_064493136.1 NZ_CP026675:c488568-488272 [Pseudomonas sp. SWI36]
MEKRMPHCPLERVRALVGAGRISPTTASLRGAQALGMEYADMLEVITGLERRDFYKSMTSYADHRVWQDVYRPLTVKGYL
YLKLSVVDDALIVSFKEL
MEKRMPHCPLERVRALVGAGRISPTTASLRGAQALGMEYADMLEVITGLERRDFYKSMTSYADHRVWQDVYRPLTVKGYL
YLKLSVVDDALIVSFKEL
Download Length: 297 bp
>T95427 NZ_CP026675:c488568-488272 [Pseudomonas sp. SWI36]
ATGGAAAAGAGAATGCCTCATTGCCCGCTGGAGCGGGTAAGAGCACTGGTGGGCGCTGGCCGCATCAGCCCTACAACCGC
TTCCTTACGAGGCGCTCAGGCCTTGGGAATGGAATATGCGGACATGCTGGAGGTCATCACCGGTCTGGAGCGCAGAGATT
TCTACAAAAGCATGACCAGTTATGCCGACCACCGCGTTTGGCAAGATGTCTATCGGCCGCTTACGGTAAAGGGATATCTG
TACCTGAAACTGTCAGTGGTAGATGACGCGCTCATCGTGTCTTTCAAGGAGTTGTGA
ATGGAAAAGAGAATGCCTCATTGCCCGCTGGAGCGGGTAAGAGCACTGGTGGGCGCTGGCCGCATCAGCCCTACAACCGC
TTCCTTACGAGGCGCTCAGGCCTTGGGAATGGAATATGCGGACATGCTGGAGGTCATCACCGGTCTGGAGCGCAGAGATT
TCTACAAAAGCATGACCAGTTATGCCGACCACCGCGTTTGGCAAGATGTCTATCGGCCGCTTACGGTAAAGGGATATCTG
TACCTGAAACTGTCAGTGGTAGATGACGCGCTCATCGTGTCTTTCAAGGAGTTGTGA
Antitoxin
Download Length: 134 a.a. Molecular weight: 14818.86 Da Isoelectric Point: 4.6580
>AT95427 WP_019437852.1 NZ_CP026675:c488269-487868 [Pseudomonas sp. SWI36]
MRCPICGGAELALDTQDMPYRYKGESTLIPDVTGDYCSVCGEAVLSHDEAMRVSDLMSAFNRQVNALDVDPDFIVSVRKK
FDLDQREAGEIFGGGVNAFSRYENGKTKPPVALIKLFKLLDRHPELFEEVRTA
MRCPICGGAELALDTQDMPYRYKGESTLIPDVTGDYCSVCGEAVLSHDEAMRVSDLMSAFNRQVNALDVDPDFIVSVRKK
FDLDQREAGEIFGGGVNAFSRYENGKTKPPVALIKLFKLLDRHPELFEEVRTA
Download Length: 402 bp
>AT95427 NZ_CP026675:c488269-487868 [Pseudomonas sp. SWI36]
ATGAGATGCCCAATTTGCGGAGGTGCCGAGCTCGCGCTAGACACTCAGGACATGCCCTACCGGTATAAGGGGGAATCGAC
CCTGATACCTGATGTGACGGGCGATTACTGTTCTGTCTGTGGTGAGGCAGTGCTAAGTCATGACGAGGCTATGCGAGTCA
GCGATCTGATGTCTGCCTTCAATCGCCAAGTCAATGCTCTAGACGTTGATCCCGATTTCATCGTTTCCGTACGCAAGAAA
TTTGATCTGGATCAGCGGGAGGCTGGGGAAATATTCGGTGGAGGAGTCAATGCTTTTTCGCGTTATGAGAATGGCAAAAC
CAAACCGCCGGTGGCGCTGATCAAATTGTTCAAGTTGCTCGACCGTCACCCGGAGCTCTTTGAGGAAGTCAGGACTGCGT
GA
ATGAGATGCCCAATTTGCGGAGGTGCCGAGCTCGCGCTAGACACTCAGGACATGCCCTACCGGTATAAGGGGGAATCGAC
CCTGATACCTGATGTGACGGGCGATTACTGTTCTGTCTGTGGTGAGGCAGTGCTAAGTCATGACGAGGCTATGCGAGTCA
GCGATCTGATGTCTGCCTTCAATCGCCAAGTCAATGCTCTAGACGTTGATCCCGATTTCATCGTTTCCGTACGCAAGAAA
TTTGATCTGGATCAGCGGGAGGCTGGGGAAATATTCGGTGGAGGAGTCAATGCTTTTTCGCGTTATGAGAATGGCAAAAC
CAAACCGCCGGTGGCGCTGATCAAATTGTTCAAGTTGCTCGACCGTCACCCGGAGCTCTTTGAGGAAGTCAGGACTGCGT
GA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2L1I9F3 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2L1I9E4 |