Detailed information of TA system TA095072

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrG-as-bsrG/-
• Location: 15535..15832
• Replicon: chromosome
• Accession: NZ_CP026533
• Organism: Bacillus velezensis strain DKU_NT_04

Toxin (Protein)

• Gene name: bsrG
• Uniprot ID: L8EAY0
• Locus tag: C3438_RS22370
• Protein ID: WP_009967548.1
• Coordinates: 15535..15651 (+)
• Length: 39 a.a.

Antitoxin (RNA)

Gene name	as-bsrG
Locus tag	-
Coordinates	15646..15832 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C3438_RS00055	11063..12223	+	1161	WP_079891309.1	tetratricopeptide repeat protein	-
C3438_RS00060	12387..13637	-	1251	WP_104842634.1	UV damage repair protein UvrX	-
C3438_RS00065	13630..13962	-	333	WP_014472056.1	YolD-like family protein	-
C3438_RS00070	14190..14963	-	774	WP_104842635.1	sporulation protein YunB	-
C3438_RS00075	15092..15295	-	204	WP_021493638.1	hypothetical protein	-
C3438_RS22370	15535..15651	+	117	WP_009967548.1	type I toxin-antitoxin system toxin BsrG	Toxin
-	15646..15832	-	187	NuclAT_0	-	Antitoxin
-	15646..15832	-	187	NuclAT_0	-	Antitoxin
-	15646..15832	-	187	NuclAT_0	-	Antitoxin
-	15646..15832	-	187	NuclAT_0	-	Antitoxin
C3438_RS00085	16063..16551	-	489	WP_104842636.1	antitoxin YezG family protein	-
C3438_RS00090	16557..18467	-	1911	WP_104842637.1	ribonuclease YeeF family protein	-
C3438_RS00095	18643..19608	+	966	WP_104842638.1	thermonuclease family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	209..21397	21188

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-38)

Sequences

Toxin

Protein

• Length: 39 a.a.
• Molecular weight: 4336.39 Da
• Isoelectric Point: 10.1022

>T95072 WP_009967548.1 NZ_CP026533:15535-15651 [Bacillus velezensis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Nucleotide

• Length: 117 bp

>T95072 NZ_CP026533:15535-15651 [Bacillus velezensis]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin

Nucleotide

• Length: 187 bp

>AT95072 NZ_CP026533:c15832-15646 [Bacillus velezensis]
AATGATACAAATAATTATTTATTGCATTTTGATTTGTGGAAATGCATAAAATAAAAAAAGACCTGGGGTGCGCTAACACC
CACTGGTCATTGTTTGTACAAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGG
TGTCCAAACTCAAGGGAAGGTCTATTT

Structures

Toxin

• AlphaFold DB: A0A7Z7EVU9

Antitoxin